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Breast Cancer Research and Treatment
Published in: Breast Cancer Research and Treatment 3/2019

01-04-2019 | Breast Cancer | Review

Health-related quality of life of breast cancer patients in the Eastern Mediterranean region: a systematic review and meta-analysis

Authors: Seyed-Mehdi Hashemi, Abbas Balouchi, Adhra Al-Mawali, Hosein Rafiemanesh, Khadije Rezaie-Keikhaie, Salehoddin Bouya, Behroz Dehghan, Mansoureh Ashghali Farahani

Published in: Breast Cancer Research and Treatment | Issue 3/2019

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Abstract

Purpose

Breast cancer is the most common type of cancer in women around the world, and this applies to the Middle East as well. The goal of all medical care and treatment is to improve the quality of life (QoL) of patients. Accordingly, the present study aimed at evaluating the QoL of patients with breast cancer in the Middle East region.

Methods

In this meta-analysis, three electronic databases (PubMed, Web of Science, and Scopus) were searched from inception until August 2018. The hoy et tool was used to evaluate the quality of the articles included in the meta-analysis. The search, screening, quality evaluation, and data extraction were carried out by two of the researchers.

Results

Thirty-six studies conducted on 8347 Middle Eastern women with breast cancer entered the final stage. QoL was assessed by the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire in 20 studies, with 6034 patients. The mean of the reported QoL was between 31.1 and 75.6. Based on the results of the random effect method, the overall mean of the QoL was 60.5 (95% confidence interval 56.0, 65.0; I2 = 99.0%). In six studies performed on 1053 individuals, QoL was classified as good, moderate, or poor. Less than one-third of patients (21%) had a good QoL.

Conclusions

Since less than one-third of patients had a good QoL, it seems necessary to design and implement an integrated and multidimensional educational program to improve QoL of patients with breast cancer.
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Metadata
Title
Health-related quality of life of breast cancer patients in the Eastern Mediterranean region: a systematic review and meta-analysis
Authors
Seyed-Mehdi Hashemi
Abbas Balouchi
Adhra Al-Mawali
Hosein Rafiemanesh
Khadije Rezaie-Keikhaie
Salehoddin Bouya
Behroz Dehghan
Mansoureh Ashghali Farahani
Publication date
01-04-2019
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 3/2019
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-019-05131-0

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