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Breast Cancer Research and Treatment

Issue 2/2018

Content (30 Articles)

Review

Cognitive sequelae of endocrine therapy in women treated for breast cancer: a meta-analysis

E. A. Underwood, P. A. Rochon, R. Moineddin, P. E. Lee, W. Wu, K. I. Pritchard, M. C. Tierney

Preclinical study

Assessment of the functional impact of germline BRCA1/2 variants located in non-coding regions in families with breast and/or ovarian cancer predisposition

E. Santana dos Santos, S. M. Caputo, L. Castera, M. Gendrot, A. Briaux, M. Breault, S. Krieger, P. K. Rogan, E. J. Mucaki, L. J. Burke, I. Bièche, C. Houdayer, D. Vaur, D. Stoppa-Lyonnet, M. A. Brown, F. Lallemand, E. Rouleau

Open Access Preclinical study

Enrichment of high-grade tumors in breast cancer gene expression studies

M. van Seijen, A. L. Mooyaart, L. Mulder, M. Hoogstraat, C. A. Drukker, C. E. Loo, B. Pouw, G. S. Sonke, J. Wesseling, E. H. Lips

Open Access Clinical trial

Trastuzumab combined with doublet or single-agent chemotherapy as first-line therapy for HER2-positive metastatic breast cancer

Y. F. Yu, Y. Wang, T. P. Fu, K. Chen, J. Q. Liu, H. R. Yao

Open Access Clinical trial

Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast cancer

Alexios Matikas, Sara Margolin, Mats Hellström, Hemming Johansson, Nils-Olof Bengtsson, Lena Karlsson, Per Edlund, Per Karlsson, Elisabet Lidbrink, Barbro Linderholm, Henrik Lindman, Per Malmstrom, Kenneth Villman, Theodoros Foukakis, Jonas Bergh

Clinical trial

Phase II study of buparlisib (BKM120) and trastuzumab in patients with HER2+ locally advanced or metastatic breast cancer resistant to trastuzumab-based therapy

B. Pistilli, T. Pluard, A. Urruticoechea, D. Farci, A. Kong, T. Bachelot, S. Chan, H. S. Han, G. Jerusalem, P. Urban, D. Robinson, S. L. Mouhaër, E. D. Tomaso, C. Massacesi, C. Saura

Clinical trial

99mTc-rituximab as a tracer for sentinel lymph node biopsy in breast cancer patients: a single-center analysis

Jiwei Wang, Tie Fan, Yingjian He, Xue Chen, Zhaoqing Fan, Yuntao Xie, Tianfeng Wang, Jinfeng Li, Tao Ouyang

Clinical trial

A multi-center pragmatic, randomized, feasibility trial comparing standard of care schedules of filgrastim administration for primary febrile neutropenia prophylaxis in early-stage breast cancer

Mohammed F. K. Ibrahim, John Hilton, Sasha Mazzarello, Dean Fergusson, Brian Hutton, Andrew Robinson, Nadia Califaretti, Tina Hsu, Stan Gertler, Mihaela Mates, Carol Stober, Lisa Vandermeer, Ranjeeta Mallick, Mark Clemons

Open Access Clinical trial

A single institution experience with palbociclib toxicity requiring dose modifications

Jun Gong, May Cho, Kim Wai Yu, James Waisman, Yuan Yuan, Joanne Mortimer

Clinical trial

Advantages with prophylactic PEG-rhG-CSF versus rhG-CSF in breast cancer patients receiving multiple cycles of myelosuppressive chemotherapy: an open-label, randomized, multicenter phase III study

Jie Xie, Jun Cao, Jing-fen Wang, Bai-hong Zhang, Xiao-hua Zeng, Hong Zheng, Yang Zhang, Li Cai, Yu-dong Wu, Qiang Yao, Xiao-chun Zhao, Wei-dong Mao, Ai-Mei Jiang, Shao-shui Chen, Shun-e Yang, Shu-sen Wang, Jian-hong Wang, Yue-yin Pan, Bi-yong Ren, Yan-ju Chen, Li-zhi Ouyang, Kai-jian Lei, Jing-hua Gao, Wen-he Huang, Zhan Huang, Tao Shou, Yan-ling He, Jing Cheng, Yang Sun, Wei-ming Li, Shu-de Cui, Xin Wang, Zhi-guo Rao, Hu Ma, Wei Liu, Xue-yong Wu, Wei-xi Shen, Fei-lin Cao, Ze-min Xiao, Biao Wu, Shu-yan Tian, Dong Meng, Peng Shen, Bi-yun Wang, Zhonghua Wang, Jian Zhang, Leiping Wang, Xi-chun Hu

Clinical trial

CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation

Lisa Speigl, Helen Burow, Jithendra Kini Bailur, Nicole Janssen, Christina-Barbara Walter, Graham Pawelec, Christopher Shipp

Open Access Clinical trial

Relevant factors for the optimal duration of extended endocrine therapy in early breast cancer

Erik J. Blok, Judith R. Kroep, Elma Meershoek-Klein Kranenbarg, Marjolijn Duijm-de Carpentier, Hein Putter, Gerrit-Jan Liefers, Johan W. R. Nortier, Emiel J. Th. Rutgers, Caroline M. Seynaeve, Cornelis J. H. van de Velde

Clinical trial

Effects of physical exercise on markers of inflammation in breast cancer patients during adjuvant chemotherapy

Jonna K. van Vulpen, Martina E. Schmidt, Miranda J. Velthuis, Joachim Wiskemann, Andreas Schneeweiss, Roel C. H. Vermeulen, Nina Habermann, Cornelia M. Ulrich, Petra H. M. Peeters, Elsken van der Wall, Anne M. May, Karen Steindorf

Clinical trial

Impact of geriatric assessment for the therapeutic decision-making of breast cancer: results of a French survey. AFSOS and SOFOG collaborative work

Claire Falandry, Ivan Krakowski, Hervé Curé, Elisabeth Carola, Pierre Soubeyran, Olivier Guérin, Hélène Gaudin, Gilles Freyer

Epidemiology

Associations between ALDH1A1 polymorphisms, alcohol consumption, and mortality among Hispanic and non-Hispanic white women diagnosed with breast cancer: the Breast Cancer Health Disparities Study

Zhiyu Xia, Kathy B. Baumgartner, Richard N. Baumgartner, Stephanie D. Boone, Lisa M. Hines, Esther M. John, Roger Wolff, Martha L. Slattery, Avonne E. Connor

Epidemiology

Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors

Sarah J. O. Nomura, Yi-Ting Hwang, Scarlett Lin Gomez, Teresa T. Fung, Shu-Lan Yeh, Chiranjeev Dash, Laura Allen, Serena Philips, Leena Hilakivi-Clarke, Yun-Ling Zheng, Judy Huei-yu Wang

Correction

Correction to: Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors

Sarah J. O. Nomura, Yi-Ting Hwang, Scarlett Lin Gomez, Teresa T. Fung, Shu-Lan Yeh, Chiranjeev Dash, Laura Allen, Serena Philips, Leena Hilakivi-Clarke, Yun-Ling Zheng, Judy Huei-yu Wang

Epidemiology

Weak circadian rhythm increases neutropenia risk among breast cancer patients undergoing adjuvant chemotherapy

Wentao Li, Carol Chi-Hei Kwok, Dominic Chun-Wan Chan, Feng Wang, Lap Ah Tse

Epidemiology

Worse survival after breast cancer in women with anorexia nervosa

Annet Bens, Fotios C. Papadopoulos, Eero Pukkala, Anders Ekbom, Mika Gissler, Lene Mellemkjær

Epidemiology

Analysis of breast cancer in young women in the Department of Defense (DOD) database

Alexandra S. Zimmer, Kangmin Zhu, Patricia S. Steeg, Alex Wu, Margaret E. Gatti-Mays, Sanaz Soltani, Jeremy G. Perkins, Stephanie Shao, Derek Brown, Matthew Georg, Hai Hu, Craig D. Shriver, Stanley Lipkowitz

Epidemiology

Predictors of survival for breast cancer patients with a BRCA1 mutation

Steven A. Narod, Tomasz Huzarski, Jacek Gronwald, Tomasz Byrski, Elzbieta Marczyk, Cezary Cybulski, Marek Szwiec, Rafal Wisniowski, Bozena Birkenfeld, Ewa Kilar, Robert Sibilski, Ping Sun, Jan Lubinski

Epidemiology

Changes in bone mineral density in women with breast cancer receiving aromatase inhibitor therapy

Marilyn L. Kwan, Song Yao, Cecile A. Laurent, Janise M. Roh, Charles P. Quesenberry Jr., Lawrence H. Kushi, Joan C. Lo

Brief Report

PRMT5 determines the sensitivity to chemotherapeutics by governing stemness in breast cancer

Zhe Wang, Jing Kong, Ying Wu, Juliang Zhang, Ting Wang, Nanlin Li, Jing Fan, Hui Wang, Jian Zhang, Rui Ling

Brief Report

Characterization of a novel germline BRCA1 splice variant, c.5332+4delA

Ciyu Yang, Sowmya Jairam, Kimberly A. Amoroso, Mark E. Robson, Michael F. Walsh, Liying Zhang

Brief Report

Axillary staging for breast cancer during pregnancy: feasibility and safety of sentinel lymph node biopsy

S. N. Han, F. Amant, E. H. Cardonick, S. Loibl, F. A. Peccatori, O. Gheysens, C. A. Sangalli, V. Nekljudova, K. Dahl Steffensen, M. Mhallem Gziri, C. P. Schröder, C. A. R. Lok, A. Verest, P. Neven, A. Smeets, G. Pruneri, M. Cremonesi, O. Gentilini

Brief Report

Efficacy of palbociclib plus fulvestrant after everolimus in hormone receptor-positive metastatic breast cancer

Pauline du Rusquec, Clément Palpacuer, Loic Campion, Anne Patsouris, Paule Augereau, Carole Gourmelon, Marie Robert, Laurence Dumas, Folliard Caroline, Mario Campone, Jean-Sébastien Frenel

Brief Report

Genetic variation in TNFα, PPARγ, and IRS-1 genes, and their association with breast-cancer survival in the HEAL cohort

Catherine Duggan, Richard N. Baumgartner, Kathy B. Baumgartner, Leslie Bernstein, Stephanie George, Rachel Ballard, Marian L. Neuhouser, Anne McTiernan

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine