Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2019

Open Access 01-12-2019 | Bisphosphonate | Case report

Charcot neuroarthropathy of the knee due to idiopathic sensory peripheral neuropathy

Authors: Qian-Hao Yang, Peichun Hsu, You-Shui Gao, Chang-Qing Zhang

Published in: BMC Musculoskeletal Disorders | Issue 1/2019

Login to get access

Abstract

Background

Charcot neuroarthropathy is a systemic disease that generates pathological changes in the musculoskeletal system, causing instability, dislocations, and deformities. Charcot neuroarthropathy of the knee, due to either diabetes mellitus or syringomyelia, is anecdotally reported with the epidemic of the diseases. However, idiopathic sensory peripheral neuropathy can inflict osteoarticular structures directly, inducing a dysfunctional Charcot neuroarthropathy. An early diagnosis and effective relief of the symptomatic deformity is essential for the treatment.

Case presentation

We report the case of a patient with idiopathic sensory peripheral neuropathy who presented with a swelling right knee, as well as distorted and painless gait disorder, diagnosed as Charcot neuroarthropathy of the knee. Partial weight bearing with a hinged knee brace was used to correct the abnormal alignment and gait posture, and bisphosphonates were prescribed to decrease pathological bone resorption. Although the alignment and Knee Society Score got a gradual deterioration, the combination of orthosis and pharmacy could alleviate the symptom to a certain extent.

Conclusion

The diagnosis of Charcot neuroarthropathy of the knee is rare that requiring early diagnosis. The presence of features, including painlessness, numbness, and deformed arthropathy following chronic-onset algesthesia loss should be taken carefully.
Literature
1.
go back to reference Dodd A, Daniels TR. Charcot neuroarthropathy of the foot and ankle. J Bone Joint Surg Am. 2018;100(8):696–711.CrossRef Dodd A, Daniels TR. Charcot neuroarthropathy of the foot and ankle. J Bone Joint Surg Am. 2018;100(8):696–711.CrossRef
2.
go back to reference Wukich DK, Sung W. Charcot arthropathy of the foot and ankle: modern concepts and management review. J Diabetes Complicat. 2009;23(6):409–26.CrossRef Wukich DK, Sung W. Charcot arthropathy of the foot and ankle: modern concepts and management review. J Diabetes Complicat. 2009;23(6):409–26.CrossRef
3.
go back to reference Kucera T, Urban K, Sponer P. Charcot arthropathy of the knee. A case-based review. Clin Rheumatol. 2011;30(3):425–8.CrossRef Kucera T, Urban K, Sponer P. Charcot arthropathy of the knee. A case-based review. Clin Rheumatol. 2011;30(3):425–8.CrossRef
4.
go back to reference Patel A, Saini AK, Edmonds ME, Kavarthapu V. Diabetic neuropathic arthropathy of the knee: two case reports and a review of the literature. Case Rep Orthop. 2018;2018:9301496.PubMedPubMedCentral Patel A, Saini AK, Edmonds ME, Kavarthapu V. Diabetic neuropathic arthropathy of the knee: two case reports and a review of the literature. Case Rep Orthop. 2018;2018:9301496.PubMedPubMedCentral
5.
go back to reference Li G, Ding Y, Zhang C, Huang H. Syringomyelia with left knee Charcot arthropathy: a case report. Br J Neurosurg. 2018. p. 1–2. Li G, Ding Y, Zhang C, Huang H. Syringomyelia with left knee Charcot arthropathy: a case report. Br J Neurosurg. 2018. p. 1–2.
6.
go back to reference Hanson LF, Hanson CG, Barner KL. Idiopathic Charcot arthropathy of the knee presenting as a Bicondylar Tibial plateau fracture. J Am Acad Orthop Surg Glob Res Rev. 2018;2(7):e032.PubMedPubMedCentral Hanson LF, Hanson CG, Barner KL. Idiopathic Charcot arthropathy of the knee presenting as a Bicondylar Tibial plateau fracture. J Am Acad Orthop Surg Glob Res Rev. 2018;2(7):e032.PubMedPubMedCentral
7.
go back to reference Berli M, Vlachopoulos L, Leupi S, Boni T, Baltin C. Treatment of Charcot neuroarthropathy and osteomyelitis of the same foot: a retrospective cohort study. BMC Musculoskelet Disord. 2017;18(1):460.CrossRef Berli M, Vlachopoulos L, Leupi S, Boni T, Baltin C. Treatment of Charcot neuroarthropathy and osteomyelitis of the same foot: a retrospective cohort study. BMC Musculoskelet Disord. 2017;18(1):460.CrossRef
8.
go back to reference England JD, Asbury AK. Peripheral neuropathy. Lancet. 2004;363(9427):2151–61.CrossRef England JD, Asbury AK. Peripheral neuropathy. Lancet. 2004;363(9427):2151–61.CrossRef
9.
go back to reference Tibbo ME, Chalmers BP, Berry DJ, Pagnano MW, Lewallen DG, Abdel MP. Primary total knee arthroplasty in patients with neuropathic (Charcot) arthropathy: contemporary results. J Arthroplast. 2018;33(9):2815–20.CrossRef Tibbo ME, Chalmers BP, Berry DJ, Pagnano MW, Lewallen DG, Abdel MP. Primary total knee arthroplasty in patients with neuropathic (Charcot) arthropathy: contemporary results. J Arthroplast. 2018;33(9):2815–20.CrossRef
10.
go back to reference Rosenbaum AJ, DiPreta JA. Classifications in brief: Eichenholtz classification of Charcot arthropathy. Clin Orthop Relat Res. 2015;473(3):1168–71.CrossRef Rosenbaum AJ, DiPreta JA. Classifications in brief: Eichenholtz classification of Charcot arthropathy. Clin Orthop Relat Res. 2015;473(3):1168–71.CrossRef
11.
go back to reference Sghirlanzoni A, Pareyson D, Lauria G. Sensory neuron diseases. Lancet Neurol. 2005;4(6):349–61.CrossRef Sghirlanzoni A, Pareyson D, Lauria G. Sensory neuron diseases. Lancet Neurol. 2005;4(6):349–61.CrossRef
12.
go back to reference Callaghan BC, Price RS, Chen KS, Feldman EL. The importance of rare subtypes in diagnosis and treatment of peripheral neuropathy: a review. JAMA Neurol. 2015;72(12):1510–8.CrossRef Callaghan BC, Price RS, Chen KS, Feldman EL. The importance of rare subtypes in diagnosis and treatment of peripheral neuropathy: a review. JAMA Neurol. 2015;72(12):1510–8.CrossRef
13.
go back to reference Pitocco D, Ruotolo V, Caputo S, Mancini L, Collina CM, Manto A, et al. Six-month treatment with alendronate in acute Charcot neuroarthropathy: a randomized controlled trial. Diabetes Care. 2005;28(5):1214–5.CrossRef Pitocco D, Ruotolo V, Caputo S, Mancini L, Collina CM, Manto A, et al. Six-month treatment with alendronate in acute Charcot neuroarthropathy: a randomized controlled trial. Diabetes Care. 2005;28(5):1214–5.CrossRef
14.
go back to reference Jostel A, Jude EB. Medical treatment of Charcot neuroosteoarthropathy. Clin Podiatr Med Surg. 2008;25(1):63–9 vi-vii.CrossRef Jostel A, Jude EB. Medical treatment of Charcot neuroosteoarthropathy. Clin Podiatr Med Surg. 2008;25(1):63–9 vi-vii.CrossRef
15.
go back to reference Zeng M, Xie J, Hu Y. Total knee arthroplasty in patients with Charcot joints. Knee Surg Sports Traumatol Arthrosc. 2016;24(8):2672–7.CrossRef Zeng M, Xie J, Hu Y. Total knee arthroplasty in patients with Charcot joints. Knee Surg Sports Traumatol Arthrosc. 2016;24(8):2672–7.CrossRef
16.
go back to reference Hayashi S, Okada T, Horita K. Bilateral TKA for Charcot arthropathy associated with multiple levels of spinal canal stenoses: a case report and review of literature. J Orthop. 2017;14(1):77–80.CrossRef Hayashi S, Okada T, Horita K. Bilateral TKA for Charcot arthropathy associated with multiple levels of spinal canal stenoses: a case report and review of literature. J Orthop. 2017;14(1):77–80.CrossRef
17.
go back to reference Kim YH, Kim JS, Oh SW. Total knee arthroplasty in neuropathic arthropathy. J Bone Joint Surg Br. 2002;84(2):216–9.CrossRef Kim YH, Kim JS, Oh SW. Total knee arthroplasty in neuropathic arthropathy. J Bone Joint Surg Br. 2002;84(2):216–9.CrossRef
18.
go back to reference Parvizi J, Marrs J, Morrey BF. Total knee arthroplasty for neuropathic (Charcot) joints. Clin Orthop Relat Res. 2003;416:145–50.CrossRef Parvizi J, Marrs J, Morrey BF. Total knee arthroplasty for neuropathic (Charcot) joints. Clin Orthop Relat Res. 2003;416:145–50.CrossRef
19.
go back to reference Chalmers BP, Tibbo ME, Trousdale RT, Lewallen DG, Berry DJ, Abdel MP. Primary total hip arthroplasty for Charcot arthropathy is associated with high complications but improved clinical outcomes. J Arthroplast. 2018;33(9):2912–8.CrossRef Chalmers BP, Tibbo ME, Trousdale RT, Lewallen DG, Berry DJ, Abdel MP. Primary total hip arthroplasty for Charcot arthropathy is associated with high complications but improved clinical outcomes. J Arthroplast. 2018;33(9):2912–8.CrossRef
20.
go back to reference Figueiredo A, Ferreira R, Alegre C, Fonseca F. Charcot osteoarthropathy of the knee secondary to neurosyphilis: a rare condition managed by a challenging arthrodesis. BMJ Case Rep. 2018;2018:bcr-2018. Figueiredo A, Ferreira R, Alegre C, Fonseca F. Charcot osteoarthropathy of the knee secondary to neurosyphilis: a rare condition managed by a challenging arthrodesis. BMJ Case Rep. 2018;2018:bcr-2018.
21.
go back to reference Nambiar M, Onggo JR, Pai V. Neuropathic arthropathy of the shoulder joint secondary to a syringomyelia. BMJ Case Rep. 2018;11(1):e228228.CrossRef Nambiar M, Onggo JR, Pai V. Neuropathic arthropathy of the shoulder joint secondary to a syringomyelia. BMJ Case Rep. 2018;11(1):e228228.CrossRef
22.
go back to reference Choudhury P, Mohapatra A, Kharat A, Chauhan V. Neuropathic arthropathy of the shoulder joint caused by syringomyelia: report of a rare case. BMJ Case Rep. 2019;12(3):e229494.CrossRef Choudhury P, Mohapatra A, Kharat A, Chauhan V. Neuropathic arthropathy of the shoulder joint caused by syringomyelia: report of a rare case. BMJ Case Rep. 2019;12(3):e229494.CrossRef
Metadata
Title
Charcot neuroarthropathy of the knee due to idiopathic sensory peripheral neuropathy
Authors
Qian-Hao Yang
Peichun Hsu
You-Shui Gao
Chang-Qing Zhang
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2019
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-019-2873-9

Other articles of this Issue 1/2019

BMC Musculoskeletal Disorders 1/2019 Go to the issue