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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2008

Open Access 01-12-2008 | Case report

Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy

Authors: Margaret I Liang, William E Carson III

Published in: World Journal of Surgical Oncology | Issue 1/2008

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Abstract

Background

Lymphazurin 1% blue dye can cause a severe anaphylactic reaction in approximately 1–3% of patients.

Case presentation

We describe a case of intraoperative anaphylaxis resulting from Lymphazurin 1% blue dye. A 48-year old woman undergoing a mastectomy with sentinel lymph node biopsy experienced a biphasic anaphylactic reaction with two episodes of hypotension at 15 minutes and 2 hours, respectively, after injection of the blue dye. The late phase was initially refractory to epinephrine.

Conclusion

Early recognition, aggressive hemodynamic management, and prolonged monitoring are indicated in these patients to watch for a potential second phase anaphylactic reaction.
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Metadata
Title
Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy
Authors
Margaret I Liang
William E Carson III
Publication date
01-12-2008
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2008
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-6-79

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