Issue 2/2024
Content (11 Articles)
Open Access
Current Opinion
Could a Long-Acting Prodrug of SN-38 be Efficacious in Sacituzumab Govitecan-Resistant Tumors?
Daniel V. Santi, Gary W. Ashley, Luc Cabel, Francois-Clement Bidard
Open Access
Leading Article
Splice-Modulating Antisense Oligonucleotides as Therapeutics for Inherited Metabolic Diseases
Suxiang Chen, Saumya Nishanga Heendeniya, Bao T. Le, Kamal Rahimizadeh, Navid Rabiee, Qurat ul ain Zahra, Rakesh N. Veedu
Open Access
Review Article
Reducing Immunogenicity by Design: Approaches to Minimize Immunogenicity of Monoclonal Antibodies
Chantal T. Harris, Sivan Cohen
Cytokines
Review Article
Molecular Engineering of Interleukin-2 for Enhanced Therapeutic Activity in Autoimmune Diseases
Luke M. Tomasovic, Kathy Liu, Derek VanDyke, Charina S. Fabilane, Jamie B. Spangler
Recombinant Antibody Fragments for Immunotherapy of Parkinson’s Disease
Karen Manoutcharian, Goar Gevorkian
Review Article
Nano–Bio Interactions: Exploring the Biological Behavior and the Fate of Lipid-Based Gene Delivery Systems
Seigo Kimura, Hideyoshi Harashima
Erenumab
Original Research Article
Cardiovascular Adverse Drug Reactions of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies for Migraine Prevention: An Analysis from the European Spontaneous Adverse Event Reporting System
Emanuela Elisa Sorbara, Maria Antonietta Barbieri, Giulia Russo, Giuseppe Cicala, Edoardo Spina
Solid Tumor
Original Research Article
Safety, Tolerability, and Preliminary Efficacy of Serplulimab, a Novel Anti-PD-1 Antibody, in Patients with Metastatic or Recurrent Solid Tumors: A Phase I Study
Ching-Liang Ho, Tsu-Yi Chao, Chia-Lun Chang, Hsuan-Yu Lin
Open Access
Original Research Article
Unveiling the Biosimilar Paradox of Oncologists’ Perceptions and Hesitations in South Korea: A Web-Based Survey Study
Gyeongseon Shin, Byung Soo Kim, Do Yeun Kim, SeungJin Bae
Systemic Lupus Erythematosus
Original Research Article
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of the Anti-IFNAR1 Monoclonal Antibody QX006N: A First-in-Human Single Ascending Dose Study in Healthy Chinese Volunteers
Xiaojiao Li, Bing Li, Meng Wang, Min Fang, Jinfeng Lou, Jingrui Liu, Hong Chen, Yanhua Ding
Correction to: Is the Availability of Biosimilar Adalimumab Associated with Budget Saving? A Difference-in-Difference Analysis of 14 Countries
Hyunjung Woo, Gyeongseon Shin, Donghwan Lee, Hye-Young Kwon, SeungJin Bae