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Obesity Surgery
Published in: Obesity Surgery 4/2024

02-03-2024 | Bariatric Surgery | Commentary

Paired Comment Regarding Correlation Between Bariatric Surgery and the Risk of Multiple Myeloma: Results from an Evidence-Based Strategy

Authors: Andre Abdo, Phillip Bachour

Published in: Obesity Surgery | Issue 4/2024

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Excerpt

In this issue, Wu et al. [1] address for the first time an intriguing question regarding obesity and hematologic neoplasm (multiple myeloma) and correlate a robust relationship between reducing obesity (with bariatric surgery) and decreasing multiple myeloma incidence in a robust meta-analysis with ten eligible studies and more the 2,400,000 patients with a relative risk of 0.51 and 95% confidence interval. These findings were impressive because two other publications before 2010 have not succeeded in showing that link [2], and less powerful ones after 2010 have suggested that that relation was possible [3, 4]. …
Literature
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Clapp B, et al. Risk of non-hormonal cancer after bariatric surgery: meta-analysis of retrospective observational studies. Br J Surg. 2022;110(1):24–33.CrossRefPubMed
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Kleinstern G, et al. Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota. Blood Cancer J. 2022;12(4):67.CrossRefPubMedPubMedCentral
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Morris EV, Edwards CM. Adipokines, adiposity, and bone marrow adipocytes: dangerous accomplices in multiple myeloma. J Cell Physiol. 2018;233(12):9159–66.CrossRefPubMed
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Tentolouris A, et al. Obesity and multiple myeloma: emerging mechanisms and perspectives. Semin Cancer Biol. 2023;92:45–60.CrossRefPubMed
Metadata
Title
Paired Comment Regarding Correlation Between Bariatric Surgery and the Risk of Multiple Myeloma: Results from an Evidence-Based Strategy
Authors
Andre Abdo
Phillip Bachour
Publication date
02-03-2024
Publisher
Springer US
Published in
Obesity Surgery / Issue 4/2024
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-024-07116-5

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