Skip to main content
Top
Published in: Obesity Surgery 11/2015

01-11-2015 | Original Contributions

Bariatric Surgery in Patients with Dialysis-Dependent Renal Failure

Authors: Anthony B. Mozer, John R. Pender IV, William H. H. Chapman, Megan E. Sippey, Walter J. Pories, Konstantinos Spaniolas

Published in: Obesity Surgery | Issue 11/2015

Login to get access

Abstract

Background

Laparoscopic procedures for the treatment of morbid obesity are commonly offered to patients with comorbidities previously thought to carry prohibitive operative risk. In this study, we reviewed characteristics and perioperative outcomes of patients with dialysis-dependent renal failure (DDRF) who underwent laparoscopic bariatric procedures.

Methods

The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2006 to 2011 was reviewed. Preoperative characteristics and 30-day outcome data of patients who underwent three common laparoscopic procedures were analyzed using ANOVA and Pearson chi-squared tests.

Results

One hundred thirty-eight patients (52.5 % female) with DDRF and a median body mass index (BMI) of 45.5 kg/m2 were identified; 33.8 % (n = 47) underwent laparoscopic banding (LAGB), 48.9 % (n = 68) laparoscopic Roux-en-Y gastric bypass (RYGB), and 16.5 % (n = 23) laparoscopic sleeve gastrectomy (LSG). No differences were found among groups in age, prevalence of American Society of Anesthesiology IV classification, BMI, weight, gender, prevalence of diabetes, and vascular or neurologic comorbidities. Total operation time and length of hospital stay were significantly different between groups. Mortality was 0.7 %, and overall morbidity was 5.8 %. The case mix reflected a decrease in LAGB procedures from 45.5 to 23.3 % from 2006–2009 to 2010–2011 and an increase in LSG procedures from 9.1 to 24.7 % (p < 0.006).

Conclusions

When performed in selected DDRF patients, bariatric surgery is safe. An increase in LSG with a concurrent decline in LAGB procedures was demonstrated over the period of the study.
Literature
1.
go back to reference Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8). Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8).
2.
go back to reference Tariq N, Moore LW, Sherman V. Bariatric surgery and end-stage organ failure. Surg Clin N Am. 2013;93(6):1359–71.CrossRefPubMed Tariq N, Moore LW, Sherman V. Bariatric surgery and end-stage organ failure. Surg Clin N Am. 2013;93(6):1359–71.CrossRefPubMed
3.
go back to reference Mokdad AH, Marks JS, Stroup DF, et al. Actual causes of death in the United States, 2000. JAMA. 2004;291(10):1238–45.CrossRefPubMed Mokdad AH, Marks JS, Stroup DF, et al. Actual causes of death in the United States, 2000. JAMA. 2004;291(10):1238–45.CrossRefPubMed
4.
go back to reference Finkelstein EA, Trogdon JG, Cohen JW, et al. Annual medical spending attributable to obesity: payer- and service-specific estimates. Health Aff. 2009;28(5):822–31.CrossRef Finkelstein EA, Trogdon JG, Cohen JW, et al. Annual medical spending attributable to obesity: payer- and service-specific estimates. Health Aff. 2009;28(5):822–31.CrossRef
5.
go back to reference Flum DR, Belle SH, King WC, et al. Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med. 2009;361(5):445–54.CrossRefPubMed Flum DR, Belle SH, King WC, et al. Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med. 2009;361(5):445–54.CrossRefPubMed
6.
go back to reference Mingrone G, Panunzi S, DeGaetano A, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012;366(17):1577–85.CrossRefPubMed Mingrone G, Panunzi S, DeGaetano A, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012;366(17):1577–85.CrossRefPubMed
7.
go back to reference Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222(3):339–52.PubMedCentralCrossRefPubMed Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222(3):339–52.PubMedCentralCrossRefPubMed
8.
go back to reference Sjostrom L. Review of the key results from the Swedish obese subjects (SOS) trial—a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273:219–34.CrossRefPubMed Sjostrom L. Review of the key results from the Swedish obese subjects (SOS) trial—a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273:219–34.CrossRefPubMed
9.
go back to reference Ortiz A, Covic A, Fliser D, et al. Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure. Lancet. 2014;383:1831–43.CrossRefPubMed Ortiz A, Covic A, Fliser D, et al. Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure. Lancet. 2014;383:1831–43.CrossRefPubMed
10.
go back to reference Iannuzzi JC, Deeb AP, Rickles AS, et al. Recognizing risk: bowel resection in the chronic renal failure population. J Gastrointest Surg. 2013;17:188–94.CrossRefPubMed Iannuzzi JC, Deeb AP, Rickles AS, et al. Recognizing risk: bowel resection in the chronic renal failure population. J Gastrointest Surg. 2013;17:188–94.CrossRefPubMed
11.
go back to reference Gajdos C, Hawn MT, Kile D, et al. General surgical procedures in patients on long-term dialysis. JAMA Surg. 2013;148(2):137–43.CrossRefPubMed Gajdos C, Hawn MT, Kile D, et al. General surgical procedures in patients on long-term dialysis. JAMA Surg. 2013;148(2):137–43.CrossRefPubMed
12.
go back to reference Itani KM. Fifteen years of the National Surgical Quality Improvement Program in review. Am J Surg. 2009;198(5 Suppl):S9–18.CrossRefPubMed Itani KM. Fifteen years of the National Surgical Quality Improvement Program in review. Am J Surg. 2009;198(5 Suppl):S9–18.CrossRefPubMed
13.
go back to reference Spaniolas K, Trus TL, Adrales GL, et al. Early morbidity and mortality of laparoscopic sleeve gastrectomy and gastric bypass in the elderly: a NSQIP analysis. Surg Obes Relat Dis. 2014;10(4):584–8.CrossRefPubMed Spaniolas K, Trus TL, Adrales GL, et al. Early morbidity and mortality of laparoscopic sleeve gastrectomy and gastric bypass in the elderly: a NSQIP analysis. Surg Obes Relat Dis. 2014;10(4):584–8.CrossRefPubMed
14.
go back to reference Turgeon NA, Perez S, Mondestin M, et al. The impact of renal function on outcomes of bariatric surgery. J Am Soc Nephrol. 2012;23:885–94.CrossRefPubMed Turgeon NA, Perez S, Mondestin M, et al. The impact of renal function on outcomes of bariatric surgery. J Am Soc Nephrol. 2012;23:885–94.CrossRefPubMed
15.
go back to reference Drolet S, Maclean AR, Myers RP, et al. Morbidity and mortality following colorectal surgery in patients with end-stage renal failure: a population-based study. Dis Colon Rectum. 2010;53(11):1508–16.CrossRefPubMed Drolet S, Maclean AR, Myers RP, et al. Morbidity and mortality following colorectal surgery in patients with end-stage renal failure: a population-based study. Dis Colon Rectum. 2010;53(11):1508–16.CrossRefPubMed
16.
go back to reference Rao A, Polanco A, Chin E, et al. Safety of elective laparoscopic cholecystectomy in patients on dialysis: an analysis of the ACS NSQIP database. Surg Endosc. 2014;28:2208–12.CrossRefPubMed Rao A, Polanco A, Chin E, et al. Safety of elective laparoscopic cholecystectomy in patients on dialysis: an analysis of the ACS NSQIP database. Surg Endosc. 2014;28:2208–12.CrossRefPubMed
17.
go back to reference Wittgrove AC, Clark GW, Tremblay LJ. Laparoscopic gastric bypass, Roux-en-Y: preliminary report of five cases. Obes Surg. 1994;4:353–7.CrossRefPubMed Wittgrove AC, Clark GW, Tremblay LJ. Laparoscopic gastric bypass, Roux-en-Y: preliminary report of five cases. Obes Surg. 1994;4:353–7.CrossRefPubMed
18.
go back to reference Santry HP, Gillen DL, Lauderdale DS. Trends in bariatric surgical procedures. JAMA. 2005;294(15):1909–17.CrossRefPubMed Santry HP, Gillen DL, Lauderdale DS. Trends in bariatric surgical procedures. JAMA. 2005;294(15):1909–17.CrossRefPubMed
19.
go back to reference Nguyen NT, Nguyen B, Gebhart A, et al. Changes in the makeup of bariatric surgery: a national increase in use of laparoscopic sleeve gastrectomy. J Am Coll Surg. 2013;216(2):252–7.CrossRefPubMed Nguyen NT, Nguyen B, Gebhart A, et al. Changes in the makeup of bariatric surgery: a national increase in use of laparoscopic sleeve gastrectomy. J Am Coll Surg. 2013;216(2):252–7.CrossRefPubMed
21.
go back to reference Regan JP, Inabnet WB, Gagner M, et al. Roux-en-Y gastric bypass as an alternative in the super-super obese patient. Obes Surg. 2003;13:861–4.CrossRefPubMed Regan JP, Inabnet WB, Gagner M, et al. Roux-en-Y gastric bypass as an alternative in the super-super obese patient. Obes Surg. 2003;13:861–4.CrossRefPubMed
22.
go back to reference Himpens J, Dapri G, Cadiere GB. A prospective randomized study between laparoscopic gastric banding and laparoscopic isolated sleeve gastrectomy: results after 1 and 3 years. Obes Surg. 2006;16:1450–6.CrossRefPubMed Himpens J, Dapri G, Cadiere GB. A prospective randomized study between laparoscopic gastric banding and laparoscopic isolated sleeve gastrectomy: results after 1 and 3 years. Obes Surg. 2006;16:1450–6.CrossRefPubMed
23.
24.
go back to reference Abou-Mrad RM, Abu-Alfa AK, Ziyadeh FN. Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients. Am J Physiol Renal Physiol. 2013;305(5):F613–7.CrossRefPubMed Abou-Mrad RM, Abu-Alfa AK, Ziyadeh FN. Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients. Am J Physiol Renal Physiol. 2013;305(5):F613–7.CrossRefPubMed
25.
go back to reference Navaneethan SD, Yehnert H. Bariatric surgery and progression of chronic kidney disease. Surg Obes Relat Dis. 2009;5(6):662–5.CrossRefPubMed Navaneethan SD, Yehnert H. Bariatric surgery and progression of chronic kidney disease. Surg Obes Relat Dis. 2009;5(6):662–5.CrossRefPubMed
26.
go back to reference Alexander JW, Goodman HR, Martin Hawver LR, et al. Improvement and stabilization of chronic kidney disease after gastric bypass. Surg Obes Relat Dis. 2009;5:237–41.CrossRefPubMed Alexander JW, Goodman HR, Martin Hawver LR, et al. Improvement and stabilization of chronic kidney disease after gastric bypass. Surg Obes Relat Dis. 2009;5:237–41.CrossRefPubMed
27.
go back to reference Srinivas TR, Meier-Kriesche H. Obesity and kidney transplantation. Semin Nephrol. 2013;33(1):34–43.CrossRefPubMed Srinivas TR, Meier-Kriesche H. Obesity and kidney transplantation. Semin Nephrol. 2013;33(1):34–43.CrossRefPubMed
28.
go back to reference Pondrom S, The AJT. Report: how big is too big? Amer J Trans. 2012;12:1663–4.CrossRef Pondrom S, The AJT. Report: how big is too big? Amer J Trans. 2012;12:1663–4.CrossRef
29.
go back to reference Takata MC, Campos GM, Clovica R, et al. Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation. Surg Obes Relat Dis. 2008;4(2):159–64.CrossRefPubMed Takata MC, Campos GM, Clovica R, et al. Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation. Surg Obes Relat Dis. 2008;4(2):159–64.CrossRefPubMed
30.
go back to reference Lin MY, Tavakol MM, Sarin A, et al. Laparoscopic sleeve gastrectomy is safe and efficacious for pretransplant candidates. Surg Obes Relat Dis. 2013;9(5):653–8.CrossRefPubMed Lin MY, Tavakol MM, Sarin A, et al. Laparoscopic sleeve gastrectomy is safe and efficacious for pretransplant candidates. Surg Obes Relat Dis. 2013;9(5):653–8.CrossRefPubMed
31.
go back to reference Choudhury RA, Murayama KM, Abt PL, et al. Roux-en-Y gastric bypass compared with aggressive diet and exercise therapy for morbidly obese patients awaiting renal transplant: a decision analysis. Surg Obes Relat Dis. 2014;10:79–87.CrossRefPubMed Choudhury RA, Murayama KM, Abt PL, et al. Roux-en-Y gastric bypass compared with aggressive diet and exercise therapy for morbidly obese patients awaiting renal transplant: a decision analysis. Surg Obes Relat Dis. 2014;10:79–87.CrossRefPubMed
Metadata
Title
Bariatric Surgery in Patients with Dialysis-Dependent Renal Failure
Authors
Anthony B. Mozer
John R. Pender IV
William H. H. Chapman
Megan E. Sippey
Walter J. Pories
Konstantinos Spaniolas
Publication date
01-11-2015
Publisher
Springer US
Published in
Obesity Surgery / Issue 11/2015
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1656-0

Other articles of this Issue 11/2015

Obesity Surgery 11/2015 Go to the issue