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Should we think twice when prescribing PPIs?

Proton pump inhibitors are a common and effective treatment for acid-related disorders, but reported adverse effects demand consideration.

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Editor's Choice

Benralizumab best for treating acute eosinophilic exacerbations

Benralizumab significantly reduces treatment failure rates and improves symptoms of eosinophilic exacerbations versus prednisolone in people with asthma or chronic obstructive pulmonary disease.

Clinical remission possible for severe asthma

Clinical remission is a realistic treatment goal for a minority of people with severe asthma treated with biologics.

Tracheal stenosis misdiagnosed as asthma

This case highlights that tracheal stenosis should be considered as a differential diagnosis in children presenting with the signs and symptoms of respiratory distress, particularly if the patient has a history of intubation.

Diabetes treatments reduce asthma attack risk

Metformin significantly reduces asthma exacerbations, and the effect is greater still with add-on glucagon-like peptide-1 receptor agonists.

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Keynote webinar | Spotlight on medication adherence

Medication non-adherence is a major barrier to effective healthcare delivery; half of all patients do not follow their doctor’s recommendations or treatment plan.

Our experts explain the fundamentals with a practical discussion of how to manage non-adherence in two common scenarios: hypertension and asthma control.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
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Case Studies

Tracheal stenosis misdiagnosed as asthma

This case highlights that tracheal stenosis should be considered as a differential diagnosis in children presenting with the signs and symptoms of respiratory distress, particularly if the patient has a history of intubation.

Remission of eosinophilic esophagitis in an elderly patient treated with benralizumab

A case of EoE complicated by bronchial asthma in an elderly patient. The EoE did not respond to conventional therapy, but improved rapidly after benralizumab was introduced and did not recur after it was discontinued.

Current Reviews

A Brief Report on a Systematic Review of Real-World Effectiveness Studies of ICS/LAMA/LABA for Treatment of Adults with Asthma in the US

The United States (US) Centers for Disease Control and Prevention report that 7.7% of the US population live with asthma, representing approximately 25 million people [ 1 ]. A previous real-world study of asthma burden in US patients receiving …

Effect of Zataria multiflora supplementation on pro- or anti-inflammatory markers: a systematic review and meta-analysis of randomized placebo-controlled trials

The aim of this study was to investigate the effectiveness of Zataria multiflora and carvacrol supplementation on inflammatory markers (IL-2, IL-4, IL-5, IL-6, TNF-α, IL-8, IL-10, interferon gamma (IFN-γ), C-reactive protein (CRP), monocyte …

Association between electronic cigarette use and respiratory outcomes among people with no established smoking history: a comprehensive review and critical appraisal

Nicotine consumption in many countries is shifting away from combustible cigarettes and toward electronic cigarettes (ECs). Understanding the overall population-level impact requires weighing their possible benefits (e.g., for smoking …

Artificial intelligence in pediatric allergy research

Atopic dermatitis, food allergy, allergic rhinitis, and asthma are among the most common diseases in childhood. They are heterogeneous diseases, can co-exist in their development, and manifest complex associations with other disorders and …

Further Reading

Unveiling the Complexities of Pediatric Asthma Treatment: Evidence, Controversies, and Emerging Approaches

Pediatric asthma remains a prevalent and challenging chronic condition globally, affecting quality of life and imposing significant burdens on families and healthcare systems. Despite advancements in understanding asthma pathophysiology and …

Costs and Complications of Respiratory Syncytial Virus and Acute Respiratory Infections in the Adult Population: Analysis of a German Claims Database

Acute respiratory infections (ARIs) caused by respiratory syncytial virus (RSV) may lead to a broad spectrum of presentations, from asymptomatic disease to severe lower respiratory tract disease (LRTD). Patients at a higher risk of severe RSV …

Understanding the role of asthma in acute chest syndrome: a comparative analysis of patients with and without asthma

While asthma is a known risk factor for Acute Chest Syndrome (ACS) and may increase overall mortality in SCD patients, this study specifically focuses on the rate of inpatient mortality, hospital stay, and costs in SCD patients who develop ACS.

The role of an anti-reflux diet in the treatment of chronic cough caused by laryngopharyngeal reflux

Laryngopharyngeal reflux (LPR) is a condition in which stomach contents flow back into the larynx and pharynx, causing irritation and various symptoms—including chronic cough, defined as a cough lasting over 3 months. More than 20% of patients …