Skip to main content
Top
Published in: BMC Cardiovascular Disorders 1/2021

Open Access 01-12-2021 | Research article

Associations between essential medicines and health outcomes for cardiovascular disease

Authors: Liane Steiner, Shawn Fraser, Darshanand Maraj, Nav Persaud

Published in: BMC Cardiovascular Disorders | Issue 1/2021

Login to get access

Abstract

Background

National essential medicines lists are used to guide medicine reimbursement and public sector medicine procurement for many countries therefore medicine listings may impact health outcomes.

Methods

Countries’ national essential medicines lists were scored on whether they listed proven medicines for ischemic heart disease, cerebrovascular disease and hypertensive heart disease. In this cross sectional study linear regression was used to measure the association between countries’ medicine coverage scores and healthcare access and quality scores.

Results

There was an association between healthcare access and quality scores and health expenditure for ischemic heart disease (p ≤ 0.001), cerebrovascular disease (p ≤ 0.001) and hypertensive heart disease (p ≤ 0.001). However, there was no association between medicine coverage scores and healthcare access and quality scores for ischemic heart disease (p = 0.252), cerebrovascular disease (p = 0.194) and hypertensive heart disease (p = 0.209) when country characteristics were accounted for.

Conclusions

Listing more medicines on national essential medicines lists may only be one factor in reducing mortality from cardiovascular disease and improving healthcare access and quality scores.
Appendix
Available only for authorised users
Literature
2.
go back to reference Bazargani UM, de Boer A, Leufkens HGM, Mantel-Teeuwisse AK. Selection of essential medicines for the prevention and treatment of cardiovascular diseases in low and middle income countries. BMC Cardiovasc Disord. 2018;25(18):126.CrossRef Bazargani UM, de Boer A, Leufkens HGM, Mantel-Teeuwisse AK. Selection of essential medicines for the prevention and treatment of cardiovascular diseases in low and middle income countries. BMC Cardiovasc Disord. 2018;25(18):126.CrossRef
4.
go back to reference Fullman N, Yearwood J, Abay SM, Abbafati C, Abd-Allah F, Abdela J, et al. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet. 2018;391:2236–71.CrossRef Fullman N, Yearwood J, Abay SM, Abbafati C, Abd-Allah F, Abdela J, et al. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet. 2018;391:2236–71.CrossRef
10.
go back to reference Persaud N, Jiang M, Shaikh R, Bali A, Oronsaye E, Woods H, et al. Comparison of essential medicines lists in 137 countries. Bull World Health Organ. 2019;97:394.CrossRef Persaud N, Jiang M, Shaikh R, Bali A, Oronsaye E, Woods H, et al. Comparison of essential medicines lists in 137 countries. Bull World Health Organ. 2019;97:394.CrossRef
12.
go back to reference The World Health Organization. Prevention and control of noncommunicable diseases: guidelines for primary health care in low resource settings. 2012;68. The World Health Organization. Prevention and control of noncommunicable diseases: guidelines for primary health care in low resource settings. 2012;68.
14.
go back to reference The World Health Organization. Tackling NCDS - Best Buys. 2017; https://apps.who.int/iris/bitstream/handle/10665/259232/WHO-NMH-NVI-17.9-eng.pdf;jsessionid=8BC070A284E32E92FA7273189F82E9DD?sequence=1. The World Health Organization. Tackling NCDS - Best Buys. 2017; https://​apps.​who.​int/​iris/​bitstream/​handle/​10665/​259232/​WHO-NMH-NVI-17.​9-eng.​pdf;jsessionid=8BC070A284E32E92FA7273189F82E9DD?sequence=1.
18.
go back to reference WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index 2018. Norwegian Institute of Public Health; 2018. WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index 2018. Norwegian Institute of Public Health; 2018.
20.
go back to reference Backman G, Hunt P, Khosla R, Jaramillo-Strouss C, Fikre BM, Rumble C, et al. Health systems and the right to health: an assessment of 194 countries. Lancet. 2008;372(9655):2047–85.CrossRef Backman G, Hunt P, Khosla R, Jaramillo-Strouss C, Fikre BM, Rumble C, et al. Health systems and the right to health: an assessment of 194 countries. Lancet. 2008;372(9655):2047–85.CrossRef
22.
go back to reference Vedanthan R, Tuikong N, Kofler C, Blank E, Kamano JH, Naanyu V, et al. Barriers and facilitators to nurse management of hypertension: a qualitative analysis from western Kenya. Ethn Dis. 2016;26(3):315–22.CrossRef Vedanthan R, Tuikong N, Kofler C, Blank E, Kamano JH, Naanyu V, et al. Barriers and facilitators to nurse management of hypertension: a qualitative analysis from western Kenya. Ethn Dis. 2016;26(3):315–22.CrossRef
23.
go back to reference Mercer T, Njuguna B, Bloomfield GS, Dick J, Finkelstein E, Kamano J, et al. Strengthening referral networks for management of hypertension across the health system (STRENGTHS) in western Kenya: a study protocol of a cluster randomized trial. Trials. 2019;20(1):554.CrossRef Mercer T, Njuguna B, Bloomfield GS, Dick J, Finkelstein E, Kamano J, et al. Strengthening referral networks for management of hypertension across the health system (STRENGTHS) in western Kenya: a study protocol of a cluster randomized trial. Trials. 2019;20(1):554.CrossRef
24.
go back to reference Kruk ME, Gage AD, Joseph NT, Danaei G, García-Saisó S, Salomon JA. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries. Lancet. 2018;392(10160):2203–12.CrossRef Kruk ME, Gage AD, Joseph NT, Danaei G, García-Saisó S, Salomon JA. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries. Lancet. 2018;392(10160):2203–12.CrossRef
Metadata
Title
Associations between essential medicines and health outcomes for cardiovascular disease
Authors
Liane Steiner
Shawn Fraser
Darshanand Maraj
Nav Persaud
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2021
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-021-01955-1

Other articles of this Issue 1/2021

BMC Cardiovascular Disorders 1/2021 Go to the issue