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Arthritis Research & Therapy

Issue 6/2012

Content (49 Articles)

Review

Epigenetic contributions in the development of rheumatoid arthritis

Kerstin Klein, Caroline Ospelt, Steffen Gay

Review

Biologic adjuvants for fracture healing

Mandeep S Virk, Jay R Lieberman

Review

An update on the hyper-IgE syndromes

Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher

Open Access Research article

Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains

Tsvetelina Batsalova, Ingrid Lindh, Johan Bäcklund, Balik Dzhambazov, Rikard Holmdahl

Open Access Research article

Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model

Steve Horvath, Abu NM Nazmul-Hossain, Rodney PE Pollard, Frans GM Kroese, Arjan Vissink, Cees GM Kallenberg, Fred KL Spijkervet, Hendrika Bootsma, Sara A Michie, Sven U Gorr, Ammon B Peck, Chaochao Cai, Hui Zhou, David TW Wong

Open Access Research article

Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease

Sebastien Viatte, Edward Flynn, Mark Lunt, Joanne Barnes, Madeleine Singwe-Ngandeu, Sylvette Bas, Anne Barton, Cem Gabay

Open Access Research article

Citrullination of fibronectin modulates synovial fibroblast behavior

Miriam A Shelef, David A Bennin, Deane F Mosher, Anna Huttenlocher

Open Access Research article

Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study

Shuji Obata, Koji Akeda, Takao Imanishi, Koichi Masuda, Won Bae, Ryo Morimoto, Yumiko Asanuma, Yuichi Kasai, Atsumasa Uchida, Akihiro Sudo

Open Access Research article

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity

Atsushi Tanaka, Hiroshi Tsukamoto, Hiroki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Yasushi Inoue, Yojirou Arinobu, Hiroaki Niiro, Takahiko Horiuchi, Koichi Akashi

Open Access Research article

Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice

Flavia SA Pelegrino, Eugene A Volpe, Niral B Gandhi, De-Quan Li, Stephen C Pflugfelder, Cintia S de Paiva

Open Access Research article

Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia

Yu Shang, Katelyn Gurley, Brock Symons, Douglas Long, Ratchakrit Srikuea, Leslie J Crofford, Charlotte A Peterson, Guoqiang Yu

Open Access Research article

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro

Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang

Open Access Research article

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

Tania N Crotti, Anak ASSK Dharmapatni, Ekram Alias, Andrew CW Zannettino, Malcolm D Smith, David R Haynes

Open Access Research article

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3

Marije Oosting, Kathrin Buffen, Subbarao RK Malireddi, Patrick Sturm, Ineke Verschueren, Marije I Koenders, Frank L van de Veerdonk, Jos WM van der Meer, Mihai G Netea, Thirumala-Devi Kanneganti, Leo AB Joosten

Editorial

Lupus nephritis - alarmins may sound the alarm?

Tianfu Wu, Chandra Mohan

Review

Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective

Serena Bugatti, Antonio Manzo, Roberto Caporali, Carlomaurizio Montecucco

Review

T cells in myositis

Vivianne Malmström, Paulius Venalis, Inka Albrecht

Open Access Research article

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

Jack Hutcheson, Kamala Vanarsa, Anna Bashmakov, Simer Grewal, Deena Sajitharan, Betty Y Chang, Joseph J Buggy, Xin J Zhou, Yong Du, Anne B Satterthwaite, Chandra Mohan

Open Access Research article

Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice

Zhi-Yong Xiao, Shao-Hui Chen, Jun-Ping Cheng, Wen-Xia Zhou, Yong-Xiang Zhang, Ri-Fang Yang, Liu-Hong Yun

Open Access Research article

IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis

Young-Mee Moon, Bo-Young Yoon, Yang-Mi Her, Hye-Joa Oh, Jae-Seon Lee, Kyoung-Woon Kim, Seon-Yeong Lee, Yun-Ju Woo, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho

Open Access Research article

Matrix to predict rapid radiographic progression of early rheumatoid arthritis patients from the community treated with methotrexate or leflunomide: results from the ESPOIR cohort

Bruno Fautrel, Benjamin Granger, Bernard Combe, Alain Saraux, Francis Guillemin, Xavier Le Loet

Open Access Research article

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

Chun Lai Too, Shahnaz Murad, Jasbir Singh Dhaliwal, Per Larsson, Xia Jiang, Bo Ding, Lars Alfredsson, Lars Klareskog, Leonid Padyukov

Open Access Research article

Reverse regulation of soluble receptor for advanced glycation end products and proinflammatory factor resistin and S100A12 in Kawasaki disease

Yanqi Qi, Fangqi Gong, Qing Zhang, Chunhong Xie, Wei Wang, Songling Fu

Open Access Research article

APRIL, a proliferation-inducing ligand, as a potential marker of lupus nephritis

Worapot Treamtrakanpon, Pornpen Tantivitayakul, Thitima Benjachat, Poorichaya Somparn, Wipawee Kittikowit, Somchai Eiam-ong, Asada Leelahavanichkul, Nattiya Hirankarn, Yingyos Avihingsanon

Open Access Research article

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

Katelin R Haynes, Allison R Pettit, Ran Duan, Hsu-Wen Tseng, Tibor T Glant, Matthew A Brown, Gethin P Thomas

Open Access Research article

Adherence to a treat-to-target strategy in early rheumatoid arthritis: results of the DREAM remission induction cohort

Marloes Vermeer, Hillechiena H Kuper, Hein J Bernelot Moens, Monique Hoekstra, Marcel D Posthumus, Piet LCM van Riel, Mart AFJ van de Laar

Open Access Research article

A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis

Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun

Open Access Research article

Intensity-dependent effect of treadmill running on lubricin metabolism of rat articular cartilage

Guo-Xin Ni, Lei Lei, Yue-Zhu Zhou

Open Access Research article

Association of a BMP5 microsatellite with knee osteoarthritis: case-control study

Cristina Rodriguez-Fontenla, Andrew Carr, Juan J Gomez-Reino, Aspasia Tsezou, John Loughlin, Antonio Gonzalez

Open Access Research article

The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study

Aamer Sandoo, Athanassios D Protogerou, James Hodson, Jacqueline P Smith, Evi Zampeli, Petros P Sfikakis, George D Kitas

Open Access Research article

Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro

Hyun-Ja Jeong, Sun-Young Nam, Hyun-A Oh, Na-Ra Han, Young-Sick Kim, Phil-Dong Moon, Seung-Youp Shin, Min-Ho Kim, Hyung-Min Kim

Open Access Research article

Raised circulating tenascin-C in rheumatoid arthritis

Theresa H Page, Peter J Charles, Anna M Piccinini, Vicky Nicolaidou, Peter C Taylor, Kim S Midwood

Open Access Research article

Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

Franziska G Matzkies, Stephan R Targan, Dror Berel, Carol J Landers, John D Reveille, Dermot PB McGovern, Michael H Weisman

Open Access Research article

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model

Anika I Tsuchida, Michiel Beekhuizen, Marijn Rutgers, Gerjo JVM van Osch, Joris EJ Bekkers, Arjan GJ Bot, Bernd Geurts, Wouter JA Dhert, Daniel BF Saris, Laura B Creemers

Open Access Research article

Disease activity and cognition in rheumatoid arthritis: an open label pilot study

Graham Raftery, Jiabao He, Ruth Pearce, Daniel Birchall, Julia L Newton, Andrew M Blamire, John D Isaacs

Open Access Research article

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

Erik JM Toonen, Pilar Barrera, Jaap Fransen, Arjan PM de Brouwer, Agnes M Eijsbouts, Pierre Miossec, Hubert Marotte, Hans Scheffer, Piet LCM van Riel, Barbara Franke, Marieke JH Coenen

Open Access Research article

Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus

Josefina Cortés-Hernández, Gabriela Ávila, Miquel Vilardell-Tarrés, Josep Ordi-Ros

Open Access Research article

Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes

Linghui Dai, Xin Zhang, Xiaoqing Hu, Chunyan Zhou, Yingfang Ao

Open Access Research article

Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis

Lieying Fan, Qiang Wang, Rongqing Liu, Ming Zong, Dongyi He, Hui Zhang, Yuanyuan Ding, Jianwei Ma

Open Access Research article

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

John Antoniou, Hong Tian Wang, Abdulrahman M Alaseem, Lisbet Haglund, Peter J Roughley, Fackson Mwale

Open Access Research article

Autoantibody-mediated arthritis in the absence of C3 and activating Fcγ receptors: C5 is activated by the coagulation cascade

Jennifer L Auger, Stefanie Haasken, Bryce A Binstadt

Open Access Research article

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis

Ilka Knütter, Rico Hiemann, Therese Brumma, Thomas Büttner, Kai Großmann, Marco Cusini, Francesca Pregnolato, Maria Orietta Borghi, Ursula Anderer, Karsten Conrad, Dirk Reinhold, Dirk Roggenbuck, Elena Csernok

Open Access Research article

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper Broen, Madelon C Vonk, José Luis Callejas, Patricia Carreira, Luis Rodríguez-Rodríguez, Rosa García-Portales, Miguel A González-Gay, Ivan Castellví, María Teresa Camps, Carlos Tolosa, Esther Vicente-Rabaneda, María Victoria Egurbide, Annemie J Schuerwegh, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Paul Shiels, Ariane Herrick, Jane Worthington, Christopher Denton, Timothy RDJ Radstake, Carmen Fonseca, Javier Martin

Open Access Research article

Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis

Hatice Yilmaz, Vedat Gerdan, Didem Kozaci, Dilek Solmaz, Servet Akar, Gercek Can, Aytac Gulcu, Yigit Goktay, Ismail Sari, Merih Birlik, Nurullah Akkoc, Fatos Onen

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.