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Arthritis Research & Therapy

Issue 4/2005

Content (29 Articles)

Open Access Research article

Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy

Takako Miyamae, David E Malehorn, Bonnie Lemster, Masaaki Mori, Tomoyuki Imagawa, Shumpei Yokota, William L Bigbee, Manda Welsh, Klaus Klarskov, Norihiro Nishomoto, Abbe N Vallejo, Raphael Hirsch

Open Access Research article

A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat

James C Keith Jr, Irma M Sainz, Irma Isordia-Salas, Robin A Pixley, Yelena Leathurby, Leo M Albert, Robert W Colman

Open Access Research article

Chondrocytes, synoviocytes and dermal fibroblasts all express PH-20, a hyaluronidase active at neutral pH

Hafida El Hajjaji, Ada Asbury Cole, Daniel-Henri Manicourt

Open Access Research article

Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody

Anne-Sophie Rouzière, Christian Kneitz, Arumugam Palanichamy, Thomas Dörner, Hans-Peter Tony

Open Access Research article

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration

Christine Lyn Le Maitre, Anthony J Freemont, Judith Alison Hoyland

Open Access Research article

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

Karim Raza, Francesco Falciani, S John Curnow, Emma J Ross, Chi-Yeung Lee, Arne N Akbar, Janet M Lord, Caroline Gordon, Christopher D Buckley, Mike Salmon

Open Access Research article

Dynamic magnetic resonance of the wrist in psoriatic arthritis reveals imaging patterns similar to those of rheumatoid arthritis

Marco A Cimmino, Massimiliano Parodi, Stefania Innocenti, Giulia Succio, Simone Banderali, Enzo Silvestri, Giacomo Garlaschi

Open Access Research article

Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes

Abdelhamid Liacini, Judith Sylvester, Wen Qing Li, Muhammad Zafarullah

Open Access Research article

Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score

Daniel Aletaha, Valerie PK Nell, Tanja Stamm, Martin Uffmann, Stephan Pflugbeil, Klaus Machold, Josef S Smolen

Open Access Research article

The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation

Julia J Inglis, Ahuva Nissim, Delphine M Lees, Stephen P Hunt, Yuti Chernajovsky, Bruce L Kidd

Open Access Research article

Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specimens

Takahito Tsubaki, Norimasa Arita, Takuma Kawakami, Takayuki Shiratsuchi, Haruyasu Yamamoto, Nobuo Takubo, Kazuhito Yamada, Sanpei Nakata, Sumiki Yamamoto, Masato Nose

Open Access Research article

Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes

Tanya R Da Sylva, Alison Connor, Yvonne Mburu, Edward Keystone, Gillian E Wu

Open Access Research article

Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation

Caroline Jochems, Ulrika Islander, Malin Erlandsson, Margareta Verdrengh, Claes Ohlsson, Hans Carlsten

Open Access Research article

Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis

Philip Gierer, Saleh Ibrahim, Thomas Mittlmeier, Dirk Koczan, Steffen Moeller, Jürgen Landes, Georg Gradl, Brigitte Vollmar

Open Access Research article

Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis

Allan A Young, Margaret M Smith, Susan M Smith, Martin A Cake, Peter Ghosh, Richard A Read, James Melrose, David H Sonnabend, Peter J Roughley, Christopher B Little

Open Access Research article

Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis

Jasper J Haringman, Marjolein Vinkenoog, Danielle M Gerlag, Tom JM Smeets, Aeilko H Zwinderman, Paul P Tak

Open Access Research article

Perforin deficiency attenuates collagen-induced arthritis

Kristin Bauer, Annika Knipper, Hoang Tu-Rapp, Dirk Koczan, Hans-Jürgen Kreutzer, Horst Nizze, Eilhard Mix, Hans-Juergen Thiesen, Rikard Holmdahl, Saleh M Ibrahim

Open Access Research article

Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations

Paola Margutti, Maurizio Sorice, Fabrizio Conti, Federica Delunardo, Mauro Racaniello, Cristiano Alessandri, Alessandra Siracusano, Rachele Riganò, Elisabetta Profumo, Guido Valesini, Elena Ortona

Open Access Research article

NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritis

Peter LEM van Lent, Karin CAM Nabbe, Arjen B Blom, Annet Sloetjes, Astrid EM Holthuysen, Jay Kolls, Fons AJ Van De Loo, Steven M Holland, Wim B Van Den Berg

Review

The role of the complement and the FcγR system in the pathogenesis of arthritis

Samuel Solomon, Daniela Kassahn, Harald Illges

Commentary

Soluble RAGE: a hot new biomarker for the hot joint?

Bernhard Moser, Barry I Hudson, Ann Marie Schmidt

Open Access Research article

Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis

Kazuo Yudoh, Hiroshi Nakamura, Kayo Masuko-Hongo, Tomohiro Kato, Kusuki Nishioka

Review

Modeling human arthritic diseases in nonhuman primates

Michel PM Vierboom, Margreet Jonker, Ronald E Bontrop, Bert 't Hart

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.