Published in:
01-04-2020 | Anemia | Concise Research Report
Validity of International Classification of Diseases Codes for Sickle Cell Trait and Sickle Cell Disease
Authors:
Kabir O. Olaniran, MD, MPH, Harish Seethapathy, MBBS, Sophia H. Zhao, MD, PhD, Andrew S. Allegretti, MD, MSc, Sahir Kalim, MD, MMSc, Sagar U. Nigwekar, MD, MMSc
Published in:
Journal of General Internal Medicine
|
Issue 4/2020
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Excerpt
Sickle cell trait (SCT) is increasingly being studied as a risk factor for diseases disproportionately affecting African Americans.
1 Research into sickle cell disease (SCD) is also increasing due to poor outcomes in this understudied condition.
2 Most sickle cell research uses hemoglobin electrophoresis or genetic data to identify patients. However, such information is not always collected or available in clinical care records, limiting adequate sample sizes in large databases with useful outcomes. The utility of International Classification of Diseases (ICD) codes to determine sickle cell status has not been examined in detail. We sought to determine sickle cell prevalence and the validity of sickle cell ICD codes in African American adults in a large multi-hospital healthcare system. …