Skip to main content
Top
Published in: European Journal of Nutrition 1/2022

01-02-2022 | Anemia | Review

Micronutrients deficiences in patients after bariatric surgery

Authors: Amin Gasmi, Geir Bjørklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Massimiliano Peana, Alexandru Dosa, Salva Piscopo, Asma Gasmi Benahmed, Daniel Ovidiu Costea

Published in: European Journal of Nutrition | Issue 1/2022

Login to get access

Abstract

Bariatric surgery is an effective option for managing obesity and has gained general acceptance among patients in recent years. Generally, despite the high caloric intake, a bad nutritional habit of obese people results in the deficiency of several vitamins, minerals, and trace elements essential for body metabolism and normal physiological processes. Additionally, the current bariatric surgical approaches such as sleeve gastrectomy (SG), Roux-en-Y-gastric bypass (RYGB), laparoscopic adjustable gastric banding (LAGB), and jejunoileal bypass (JIB) can cause or exacerbate these deficiencies. Based on several reports, it appears that the various bariatric surgical procedures affect nutrient absorption differently. Being purely restrictive, LAGB and SG affect the absorption of iron, selenium, and vitamin B12, while RYGB, JIB, and biliopancreatic diversion have a more profound impact on the absorption of essential vitamins, minerals, and trace elements. Nutritional deficiencies in vitamins, minerals, and trace elements may follow bariatric surgery and are associated with clinical manifestations and diseases, including anemia, ataxia, hair loss, and Wernicke encephalopathy. The present review summarizes some of the major vitamin and micronutrient deficiencies associated with bariatric surgery, particularly those presented post-surgically. To avoid any adverse consequences of vitamin and trace element deficiency, proper monitoring and tests are recommended at any stage, from pre- to post-surgery (periodical check-up), followed by specific and individual nutritional supplementation treatments and a proper healthy diet.
Literature
12.
go back to reference Mechanick JI, Apovian C, Brethauer S, Garvey WT, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman RD, Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD (2019) Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures—2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, the Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists, Executive Summary. Endocr Pract 25(12):1346–1359. https://doi.org/10.4158/GL-2019-0406CrossRefPubMed Mechanick JI, Apovian C, Brethauer S, Garvey WT, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman RD, Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD (2019) Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures—2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, the Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists, Executive Summary. Endocr Pract 25(12):1346–1359. https://​doi.​org/​10.​4158/​GL-2019-0406CrossRefPubMed
19.
go back to reference Emile SH, Elfeki H, Elalfy K, Abdallah E (2017) Laparoscopic sleeve gastrectomy then and now: an updated systematic review of the progress and short-term outcomes over the last 5 years. Surg Laparosc Endosc Percutaneous Tech 27(5):307–315CrossRef Emile SH, Elfeki H, Elalfy K, Abdallah E (2017) Laparoscopic sleeve gastrectomy then and now: an updated systematic review of the progress and short-term outcomes over the last 5 years. Surg Laparosc Endosc Percutaneous Tech 27(5):307–315CrossRef
47.
go back to reference Levin M, Katz A, Padayatty SJ (2006) Vitamin C. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ (eds) Modern nutrition in health and disease. Lippincott Williams & Wilkins, Philadelphia Levin M, Katz A, Padayatty SJ (2006) Vitamin C. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ (eds) Modern nutrition in health and disease. Lippincott Williams & Wilkins, Philadelphia
53.
go back to reference Mahmood L (2014) The metabolic processes of folic acid and Vitamin B12 deficiency. J Health Res Rev 1(1):5CrossRef Mahmood L (2014) The metabolic processes of folic acid and Vitamin B12 deficiency. J Health Res Rev 1(1):5CrossRef
62.
go back to reference Klick BH (2013) Thiamine deficiency in the bariatric surgery patient—a multidisciplinary challenge in the clinic and the community. Bariatr Times 10(1):20–21 Klick BH (2013) Thiamine deficiency in the bariatric surgery patient—a multidisciplinary challenge in the clinic and the community. Bariatr Times 10(1):20–21
69.
go back to reference Ems T, St Lucia K, Huecker MR (2020) Biochemistry, iron absorption. StatPearls, Treasure Island Ems T, St Lucia K, Huecker MR (2020) Biochemistry, iron absorption. StatPearls, Treasure Island
81.
go back to reference Billeter AT, Probst P, Fischer L, Senft J, Kenngott HG, Schulte T, Clemens G, Zech U, Büchler MW, Nawroth PP, Müller-Stich BP (2015) Risk of malnutrition, trace metal, and vitamin deficiency post Roux-en-Y gastric bypass—a prospective study of 20 patients with BMI <35 kg/m2. Obes Surg 25(11):2125–2134. https://doi.org/10.1007/s11695-015-1676-9CrossRefPubMed Billeter AT, Probst P, Fischer L, Senft J, Kenngott HG, Schulte T, Clemens G, Zech U, Büchler MW, Nawroth PP, Müller-Stich BP (2015) Risk of malnutrition, trace metal, and vitamin deficiency post Roux-en-Y gastric bypass—a prospective study of 20 patients with BMI <35 kg/m2. Obes Surg 25(11):2125–2134. https://​doi.​org/​10.​1007/​s11695-015-1676-9CrossRefPubMed
91.
go back to reference Shil RSK, Alomar AF, Farooqui MR (2015) Ataxia and weakness after sleeve gastrectomy. Saudi J Obesity 3(1):26CrossRef Shil RSK, Alomar AF, Farooqui MR (2015) Ataxia and weakness after sleeve gastrectomy. Saudi J Obesity 3(1):26CrossRef
92.
go back to reference Ruiz-Tovar J, Oller I, Llavero C, Zubiaga L, Diez M, Arroyo A, Calero A, Calpena R (2014) Hair loss in females after sleeve gastrectomy: predictive value of serum zinc and iron levels. Am Surg 80(5):466–471CrossRefPubMed Ruiz-Tovar J, Oller I, Llavero C, Zubiaga L, Diez M, Arroyo A, Calero A, Calpena R (2014) Hair loss in females after sleeve gastrectomy: predictive value of serum zinc and iron levels. Am Surg 80(5):466–471CrossRefPubMed
94.
go back to reference Ciangura C, Coupaye M, Deruelle P, Gascoin G, Calabrese D, Cosson E, Ducarme G, Gaborit B, Lelievre B, Mandelbrot L, Petrucciani N, Quilliot D, Ritz P, Robin G, Salle A, Gugenheim J, Nizard J (2019) Clinical practice guidelines for childbearing female candidates for bariatric surgery, pregnancy, and post-partum management after bariatric surgery. Obes Surg 29(11):3722–3734. https://doi.org/10.1007/s11695-019-04093-yCrossRefPubMed Ciangura C, Coupaye M, Deruelle P, Gascoin G, Calabrese D, Cosson E, Ducarme G, Gaborit B, Lelievre B, Mandelbrot L, Petrucciani N, Quilliot D, Ritz P, Robin G, Salle A, Gugenheim J, Nizard J (2019) Clinical practice guidelines for childbearing female candidates for bariatric surgery, pregnancy, and post-partum management after bariatric surgery. Obes Surg 29(11):3722–3734. https://​doi.​org/​10.​1007/​s11695-019-04093-yCrossRefPubMed
97.
go back to reference Shawe J, Ceulemans D, Akhter Z, Neff K, Hart K, Heslehurst N, Stotl I, Agrawal S, Steegers-Theunissen R, Taheri S, Greenslade B, Rankin J, Huda B, Douek I, Galjaard S, Blumenfeld O, Robinson A, Whyte M, Mathews E, Devlieger R (2019) Pregnancy after bariatric surgery: consensus recommendations for periconception, antenatal and postnatal care. Obes Rev 20(11):1507–1522. https://doi.org/10.1111/obr.12927CrossRefPubMedPubMedCentral Shawe J, Ceulemans D, Akhter Z, Neff K, Hart K, Heslehurst N, Stotl I, Agrawal S, Steegers-Theunissen R, Taheri S, Greenslade B, Rankin J, Huda B, Douek I, Galjaard S, Blumenfeld O, Robinson A, Whyte M, Mathews E, Devlieger R (2019) Pregnancy after bariatric surgery: consensus recommendations for periconception, antenatal and postnatal care. Obes Rev 20(11):1507–1522. https://​doi.​org/​10.​1111/​obr.​12927CrossRefPubMedPubMedCentral
99.
go back to reference Armstrong C (2010) ACOG guidelines on pregnancy after bariatric surgery. Am Fam Physician 81(7):905 Armstrong C (2010) ACOG guidelines on pregnancy after bariatric surgery. Am Fam Physician 81(7):905
100.
go back to reference Mechanick JI, Kushner RF, Sugerman HJ, Gonzalez-Campoy JM, Collazo-Clavell ML, Spitz AF, Apovian CM, Livingston EH, Brolin R, Sarwer DB, Anderson WA, Dixon J, Guven S (2009) American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic and Bariatric Surgery medical guidelines for clinical practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient. Obesity (Silver Spring) 17(Suppl 1):S1–S70. https://doi.org/10.1038/oby.2009.28CrossRef Mechanick JI, Kushner RF, Sugerman HJ, Gonzalez-Campoy JM, Collazo-Clavell ML, Spitz AF, Apovian CM, Livingston EH, Brolin R, Sarwer DB, Anderson WA, Dixon J, Guven S (2009) American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic and Bariatric Surgery medical guidelines for clinical practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient. Obesity (Silver Spring) 17(Suppl 1):S1–S70. https://​doi.​org/​10.​1038/​oby.​2009.​28CrossRef
Metadata
Title
Micronutrients deficiences in patients after bariatric surgery
Authors
Amin Gasmi
Geir Bjørklund
Pavan Kumar Mujawdiya
Yuliya Semenova
Massimiliano Peana
Alexandru Dosa
Salva Piscopo
Asma Gasmi Benahmed
Daniel Ovidiu Costea
Publication date
01-02-2022
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nutrition / Issue 1/2022
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-021-02619-8

Other articles of this Issue 1/2022

European Journal of Nutrition 1/2022 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.