Skip to main content
Top
Published in: Obesity Surgery 1/2019

01-01-2019 | Original Contributions

Anastomotic Strictures After Roux-en-Y Gastric Bypass: a Cohort Study from the Scandinavian Obesity Surgery Registry

Authors: Kristina Almby, David Edholm

Published in: Obesity Surgery | Issue 1/2019

Login to get access

Abstract

Background

Roux-en-Y gastric bypass (RYGB) is the most common bariatric procedure worldwide. Anastomotic stricture is a known complication of RYGB. The aim was to explore the incidence and outcomes of strictures within the Scandinavian Obesity Surgery Registry (SOReg).

Method

SOReg included prospective data from 36,362 patients undergoing bariatric surgery in the years 2007–2013. Outcomes were recorded at 30-day and at 1-year follow-up according to the standard SOReg routine. The medical charts of patients suffering from stricture after RYGB were requested and assessed.

Setting

National bariatric surgery registry

Results

Anastomotic stricture within 1 year of surgery was confirmed in 101 patients representing an incidence of 0.3%. Risk factors for stricture were patient age above 60 years (odds ratio (OR), 6.2 95% confidence interval (CI) 2.7–14.3), circular stapled gastrojejunostomy (OR 2.7, 95% CI 1.4–5.5), postoperative anastomotic leak (OR 8.9 95%, CI 4.7–17.0), and marginal ulcer (OR 30.0, 95% CI 19.2–47.0). Seventy-five percent of the strictures were diagnosed within 70 days of surgery. Two dilatations or less was sufficient to successfully treat 50% of patients. Ten pecent of patients developed perforation during dilatation, and the risk of perforating at each dilatation was 3.8%. Perforation required surgery in six cases but there was no mortality. Strictures in SOReg may be underreported, which could explain the low incidence in the study.

Conclusion

Most strictures present within 2 months and are successfully treated with two dilatations or less. Dilating a strictured gastrojejunostomy entails a risk of perforation (3.8%).
Literature
1.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery worldwide 2013. Obes Surg. 2015;25(10):1822–32.CrossRefPubMed Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery worldwide 2013. Obes Surg. 2015;25(10):1822–32.CrossRefPubMed
2.
go back to reference Sjöström L, Narbro K, Sjöström CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.CrossRefPubMed Sjöström L, Narbro K, Sjöström CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.CrossRefPubMed
3.
go back to reference Kolotkin RL, Crosby RD, Gress RE, et al. Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls. Surg Obes Relat Dis. 2009;5(2):250–6.CrossRefPubMedPubMedCentral Kolotkin RL, Crosby RD, Gress RE, et al. Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls. Surg Obes Relat Dis. 2009;5(2):250–6.CrossRefPubMedPubMedCentral
4.
go back to reference Da Costa M, Mata A, Espinós J, et al. Endoscopic dilation of gastrojejunal anastomotic strictures after laparoscopic gastric bypass. Predictors of initial failure. Obes Surg. 2011;21(1):36–41.CrossRefPubMed Da Costa M, Mata A, Espinós J, et al. Endoscopic dilation of gastrojejunal anastomotic strictures after laparoscopic gastric bypass. Predictors of initial failure. Obes Surg. 2011;21(1):36–41.CrossRefPubMed
5.
go back to reference Nguyen NT, Stevens CM, Wolfe BM. Incidence and outcome of anastomotic stricture after laparoscopic gastric bypass. J Gastrointest Surg. 2003;7(8):997–1003.CrossRefPubMed Nguyen NT, Stevens CM, Wolfe BM. Incidence and outcome of anastomotic stricture after laparoscopic gastric bypass. J Gastrointest Surg. 2003;7(8):997–1003.CrossRefPubMed
6.
go back to reference Edholm D, Sundbom M. Comparison between circular-and linear-stapled gastrojejunostomy in laparoscopic Roux-en-Y gastric bypass—a cohort from the Scandinavian Obesity Registry. Surg Obes Relat Dis. 2015;11(6):1233–6.CrossRefPubMed Edholm D, Sundbom M. Comparison between circular-and linear-stapled gastrojejunostomy in laparoscopic Roux-en-Y gastric bypass—a cohort from the Scandinavian Obesity Registry. Surg Obes Relat Dis. 2015;11(6):1233–6.CrossRefPubMed
7.
go back to reference Azagury D, Dayyeh BA, Greenwalt I, et al. Marginal ulceration after Roux-en-Y gastric bypass surgery: characteristics, risk factors, treatment, and outcomes. Endoscopy. 2011;43(11):950–4.CrossRefPubMed Azagury D, Dayyeh BA, Greenwalt I, et al. Marginal ulceration after Roux-en-Y gastric bypass surgery: characteristics, risk factors, treatment, and outcomes. Endoscopy. 2011;43(11):950–4.CrossRefPubMed
8.
go back to reference Sverdén E, Mattsson F, Sondén A, et al. Risk factors for marginal ulcer after gastric bypass surgery for obesity: a population-based cohort study. Ann Surg. 2016;263(4):733–7.CrossRefPubMed Sverdén E, Mattsson F, Sondén A, et al. Risk factors for marginal ulcer after gastric bypass surgery for obesity: a population-based cohort study. Ann Surg. 2016;263(4):733–7.CrossRefPubMed
9.
go back to reference Rawlins L, Rawlins MP, Brown CC, et al. Effect of Helicobacter pylori on marginal ulcer and stomal stenosis after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2013;9(5):760–4.CrossRefPubMed Rawlins L, Rawlins MP, Brown CC, et al. Effect of Helicobacter pylori on marginal ulcer and stomal stenosis after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2013;9(5):760–4.CrossRefPubMed
10.
go back to reference Ribeiro-Parenti L, Arapis K, Chosidow D, et al. Gastrojejunostomy stricture rate: comparison between antecolic and retrocolic laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2015;11(5):1076–84.CrossRefPubMed Ribeiro-Parenti L, Arapis K, Chosidow D, et al. Gastrojejunostomy stricture rate: comparison between antecolic and retrocolic laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2015;11(5):1076–84.CrossRefPubMed
11.
go back to reference Yimcharoen P, Heneghan H, Chand B, et al. Successful management of gastrojejunal strictures after gastric bypass: is timing important? Surg Obes Relat Dis. 2012;8(2):151–7.CrossRefPubMed Yimcharoen P, Heneghan H, Chand B, et al. Successful management of gastrojejunal strictures after gastric bypass: is timing important? Surg Obes Relat Dis. 2012;8(2):151–7.CrossRefPubMed
12.
go back to reference Hedenbro J, Näslund E, Boman L, et al. Formation of the Scandinavian Obesity Surgery Registry, SOReg. Obes Surg. 2015;25(10):1–8.CrossRef Hedenbro J, Näslund E, Boman L, et al. Formation of the Scandinavian Obesity Surgery Registry, SOReg. Obes Surg. 2015;25(10):1–8.CrossRef
13.
go back to reference Dindo D, Demartines N, Clavien P-A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien P-A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.CrossRefPubMedPubMedCentral
14.
go back to reference Olbers T, Lönroth H, Fagevik-Olsén M, et al. Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome. Obes Surg. 2003;13(3):364–70.CrossRefPubMed Olbers T, Lönroth H, Fagevik-Olsén M, et al. Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome. Obes Surg. 2003;13(3):364–70.CrossRefPubMed
15.
go back to reference Huang CS, Forse RA, Jacobson BC, et al. Endoscopic findings and their clinical correlations in patients with symptoms after gastric bypass surgery. Gastrointest Endosc. 2003;58(6):859–66.CrossRefPubMed Huang CS, Forse RA, Jacobson BC, et al. Endoscopic findings and their clinical correlations in patients with symptoms after gastric bypass surgery. Gastrointest Endosc. 2003;58(6):859–66.CrossRefPubMed
16.
go back to reference DeMaria EJ, Sugerman HJ, Meador JG, et al. High failure rate after laparoscopic adjustable silicone gastric banding for treatment of morbid obesity. Ann Surg. 2001;233(6):809–18.CrossRefPubMedPubMedCentral DeMaria EJ, Sugerman HJ, Meador JG, et al. High failure rate after laparoscopic adjustable silicone gastric banding for treatment of morbid obesity. Ann Surg. 2001;233(6):809–18.CrossRefPubMedPubMedCentral
17.
go back to reference Goitein D, Papasavas P, Gagne D, et al. Gastrojejunal strictures following laparoscopic oux-en-Y gastric bypass for morbid obesity. Surg Endosc. 2005;19(5):628–32.CrossRefPubMed Goitein D, Papasavas P, Gagne D, et al. Gastrojejunal strictures following laparoscopic oux-en-Y gastric bypass for morbid obesity. Surg Endosc. 2005;19(5):628–32.CrossRefPubMed
18.
go back to reference Aghajani E, Jacobsen HJ, Nergaard BJ, et al. Internal hernia after gastric bypass: a new and simplified technique for laparoscopic primary closure of the mesenteric defects. J Gastrointest Surg. 2012;16(3):641–5.CrossRefPubMed Aghajani E, Jacobsen HJ, Nergaard BJ, et al. Internal hernia after gastric bypass: a new and simplified technique for laparoscopic primary closure of the mesenteric defects. J Gastrointest Surg. 2012;16(3):641–5.CrossRefPubMed
19.
go back to reference Vines L, Frick T, Aczél S, et al. Linear stapled gastrojejunostomy results in fewer strictures compared to circular stapled gastrojejunostomy in laparoscopic gastric bypass surgery. Langenbeck’s Arch Surg. 2017;402(6):911–6.CrossRef Vines L, Frick T, Aczél S, et al. Linear stapled gastrojejunostomy results in fewer strictures compared to circular stapled gastrojejunostomy in laparoscopic gastric bypass surgery. Langenbeck’s Arch Surg. 2017;402(6):911–6.CrossRef
20.
go back to reference Edholm D, Ottosson J, Sundbom M. Importance of pouch size in laparoscopic Roux-en-Y gastric bypass: a cohort study of 14,168 patients. Surg Endosc. 2016 May;30(5):2011–5.CrossRefPubMed Edholm D, Ottosson J, Sundbom M. Importance of pouch size in laparoscopic Roux-en-Y gastric bypass: a cohort study of 14,168 patients. Surg Endosc. 2016 May;30(5):2011–5.CrossRefPubMed
21.
go back to reference Mathew A, Veliuona MA, DePalma FJ, et al. Gastrojejunal stricture after gastric bypass and efficacy of endoscopic intervention. Dig Dis Sci. 2009;54(9):1971–8.CrossRefPubMed Mathew A, Veliuona MA, DePalma FJ, et al. Gastrojejunal stricture after gastric bypass and efficacy of endoscopic intervention. Dig Dis Sci. 2009;54(9):1971–8.CrossRefPubMed
22.
go back to reference Carrodeguas L, Szomstein S, Zundel N, et al. Gastrojejunal anastomotic strictures following laparoscopic Roux-en-Y gastric bypass surgery: analysis of 1291 patients. Surg Obes Relat Dis. 2006;2(2):92–7.CrossRefPubMed Carrodeguas L, Szomstein S, Zundel N, et al. Gastrojejunal anastomotic strictures following laparoscopic Roux-en-Y gastric bypass surgery: analysis of 1291 patients. Surg Obes Relat Dis. 2006;2(2):92–7.CrossRefPubMed
23.
go back to reference de Moura EG, Orso IR, Aurélio EF, et al. Factors associated with complications or failure of endoscopic balloon dilation of anastomotic stricture secondary to Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2016;12(3):582–6.CrossRefPubMed de Moura EG, Orso IR, Aurélio EF, et al. Factors associated with complications or failure of endoscopic balloon dilation of anastomotic stricture secondary to Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2016;12(3):582–6.CrossRefPubMed
24.
go back to reference Puig CA, Waked TM, Baron TH, et al. The role of endoscopic stents in the management of chronic anastomotic and staple line leaks and chronic strictures after bariatric surgery. Surg Obes Relat Dis. 2014;10(4):613–7.CrossRefPubMed Puig CA, Waked TM, Baron TH, et al. The role of endoscopic stents in the management of chronic anastomotic and staple line leaks and chronic strictures after bariatric surgery. Surg Obes Relat Dis. 2014;10(4):613–7.CrossRefPubMed
Metadata
Title
Anastomotic Strictures After Roux-en-Y Gastric Bypass: a Cohort Study from the Scandinavian Obesity Surgery Registry
Authors
Kristina Almby
David Edholm
Publication date
01-01-2019
Publisher
Springer US
Published in
Obesity Surgery / Issue 1/2019
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-018-3500-9

Other articles of this Issue 1/2019

Obesity Surgery 1/2019 Go to the issue