Skip to main content
Top
Published in: Scoliosis and Spinal Disorders 1/2017

Open Access 01-12-2017 | Research

An observational study on surgically treated adult idiopathic scoliosis patients’ quality of life outcomes at 1- and 2-year follow-ups and comparison to controls

Authors: Jennifer C. Theis, Anna Grauers, Elias Diarbakerli, Panayiotis Savvides, Allan Abbott, Paul Gerdhem

Published in: Scoliosis and Spinal Disorders | Issue 1/2017

Login to get access

Abstract

Background

Prospective data on health-related quality of life in patients with idiopathic scoliosis treated surgically as adults is needed. We compared preoperative and 1- and 2-year follow-up data in surgically treated adults with idiopathic scoliosis with juvenile or adolescent onset. Results were compared to untreated adults with scoliosis and population normative data.

Methods

A comparison of preoperative and 1- and 2-year follow-up data of 75 adults surgically treated for idiopathic scoliosis at a mean age of 28 years (range 18 to 69) from a prospective national register study, as well as a comparison with age- and sex-matched data from 75 untreated adults with less severe scoliosis and 75 adults without scoliosis, was made. Outcome measures were EuroQol-5 dimensions (EQ-5D) and Scoliosis Research Society (SRS)-22r questionnaire.

Results

In the surgically treated, EQ-5D and SRS-22r scores had statistically significant improvements at both 1- and 2-year follow-ups (all p< 0.015). The effect size of surgery on EQ-5D at 1-year follow-up was large (r = −0.54) and small-medium (r = −0.20) at 2-year follow-up. The effect size of surgery on SRS-22r outcomes was medium-large at 1- and 2-year follow-ups (r = −0.43 and r = −0.42 respectively). At the 2-year follow-up, the EQ-5D score and the SRS-22r subscore were similar to the untreated scoliosis group (p = 0.56 and p = 0.91 respectively), but lower than those in the adults without scoliosis (p < 0.001 for both comparisons).

Conclusions

Adults with idiopathic scoliosis experience an increase in health-related quality of life following surgery at 2-year follow-up, approaching the health-related quality of life of untreated individuals with less severe scoliosis, but remain lower than normative population data.
Literature
2.
go back to reference Cobb J. Outline for the study of scoliosis. Instructional Course Lectures, The American Academy of Orthopaedic Surgeons (AAOS). Ann Arbor. 1948;5:261–75. Cobb J. Outline for the study of scoliosis. Instructional Course Lectures, The American Academy of Orthopaedic Surgeons (AAOS). Ann Arbor. 1948;5:261–75.
3.
go back to reference Berven S, Deviren V, Demir-Deviren S, Hu SS, Bradford DS. Studies in the modified Scoliosis Research Society Outcomes Instrument in adults: validation, reliability, and discriminatory capacity. Spine (Phila Pa 1976). 2003;28(18):2164–9. discussion 2169.CrossRef Berven S, Deviren V, Demir-Deviren S, Hu SS, Bradford DS. Studies in the modified Scoliosis Research Society Outcomes Instrument in adults: validation, reliability, and discriminatory capacity. Spine (Phila Pa 1976). 2003;28(18):2164–9. discussion 2169.CrossRef
4.
go back to reference Baldus C, Bridwell KH, Harrast J, Edwards 2nd C, Glassman S, Horton W, Lenke LG, Lowe T, Mardjetko S, Ondra S, et al. Age-gender matched comparison of SRS instrument scores between adult deformity and normal adults: are all SRS domains disease specific? Spine (Phila Pa 1976). 2008;33(20):2214–8.CrossRef Baldus C, Bridwell KH, Harrast J, Edwards 2nd C, Glassman S, Horton W, Lenke LG, Lowe T, Mardjetko S, Ondra S, et al. Age-gender matched comparison of SRS instrument scores between adult deformity and normal adults: are all SRS domains disease specific? Spine (Phila Pa 1976). 2008;33(20):2214–8.CrossRef
5.
go back to reference Bago J, Climent JM, Perez-Grueso FJ, Pellise F. Outcome instruments to assess scoliosis surgery. Eur Spine J. 2013;22 Suppl 2:S195–202.CrossRefPubMed Bago J, Climent JM, Perez-Grueso FJ, Pellise F. Outcome instruments to assess scoliosis surgery. Eur Spine J. 2013;22 Suppl 2:S195–202.CrossRefPubMed
6.
go back to reference Smith JS, Lafage V, Shaffrey CI, Schwab F, Lafage R, Hostin R, O’Brien M, Boachie-Adjei O, Akbarnia BA, Mundis GM, et al. Outcomes of operative and nonoperative treatment for adult spinal deformity: a prospective, multicenter, propensity-matched cohort assessment with minimum 2-year follow-up. Neurosurgery. 2016;78(6):851–61.CrossRefPubMed Smith JS, Lafage V, Shaffrey CI, Schwab F, Lafage R, Hostin R, O’Brien M, Boachie-Adjei O, Akbarnia BA, Mundis GM, et al. Outcomes of operative and nonoperative treatment for adult spinal deformity: a prospective, multicenter, propensity-matched cohort assessment with minimum 2-year follow-up. Neurosurgery. 2016;78(6):851–61.CrossRefPubMed
7.
go back to reference Liu S, Diebo BG, Henry JK, Smith JS, Hostin R, Cunningham ME, Mundis G, Ames CP, Burton D, Bess S, et al. The benefit of nonoperative treatment for adult spinal deformity: identifying predictors for reaching a minimal clinically important difference. Spine J. 2016;16(2):210–8.CrossRefPubMed Liu S, Diebo BG, Henry JK, Smith JS, Hostin R, Cunningham ME, Mundis G, Ames CP, Burton D, Bess S, et al. The benefit of nonoperative treatment for adult spinal deformity: identifying predictors for reaching a minimal clinically important difference. Spine J. 2016;16(2):210–8.CrossRefPubMed
8.
go back to reference Everett CR, Patel RK. A systematic literature review of nonsurgical treatment in adult scoliosis. Spine (Phila Pa 1976). 2007;32(19 Suppl):S130–4.CrossRef Everett CR, Patel RK. A systematic literature review of nonsurgical treatment in adult scoliosis. Spine (Phila Pa 1976). 2007;32(19 Suppl):S130–4.CrossRef
9.
go back to reference Monticone M, Ambrosini E, Cazzaniga D, Rocca B, Motta L, Cerri C, Brayda-Bruno M, Lovi A. Adults with idiopathic scoliosis improve disability after motor and cognitive rehabilitation: results of a randomised controlled trial. Eur Spine J. 2016;25(10):3120–9.CrossRefPubMed Monticone M, Ambrosini E, Cazzaniga D, Rocca B, Motta L, Cerri C, Brayda-Bruno M, Lovi A. Adults with idiopathic scoliosis improve disability after motor and cognitive rehabilitation: results of a randomised controlled trial. Eur Spine J. 2016;25(10):3120–9.CrossRefPubMed
10.
go back to reference Paulus MC, Kalantar SB, Radcliff K. Cost and value of spinal deformity surgery. Spine (Phila Pa 1976). 2014;39(5):388–93.CrossRef Paulus MC, Kalantar SB, Radcliff K. Cost and value of spinal deformity surgery. Spine (Phila Pa 1976). 2014;39(5):388–93.CrossRef
11.
go back to reference Liang CZ, Li FC, Li H, Tao Y, Zhou X, Chen QX. Surgery is an effective and reasonable treatment for degenerative scoliosis: a systematic review. J Int Med Res. 2012;40(2):399–405.CrossRefPubMed Liang CZ, Li FC, Li H, Tao Y, Zhou X, Chen QX. Surgery is an effective and reasonable treatment for degenerative scoliosis: a systematic review. J Int Med Res. 2012;40(2):399–405.CrossRefPubMed
12.
go back to reference Yadla S, Maltenfort MG, Ratliff JK, Harrop JS. Adult scoliosis surgery outcomes: a systematic review. Neurosurg Focus. 2010;28(3):E3.CrossRefPubMed Yadla S, Maltenfort MG, Ratliff JK, Harrop JS. Adult scoliosis surgery outcomes: a systematic review. Neurosurg Focus. 2010;28(3):E3.CrossRefPubMed
13.
go back to reference Theis J, Gerdhem P, Abbott A. Quality of life outcomes in surgically treated adult scoliosis patients: a systematic review. Eur Spine J. 2014;24(7):1343–55.CrossRefPubMed Theis J, Gerdhem P, Abbott A. Quality of life outcomes in surgically treated adult scoliosis patients: a systematic review. Eur Spine J. 2014;24(7):1343–55.CrossRefPubMed
14.
go back to reference Yoshida G, Boissiere L, Larrieu D, Bourghli A, Vital JM, Gille O, Pointillart V, Challier V, Mariey R, Pellise F, et al. Advantages and disadvantages of adult spinal deformity surgery and its impact on health-related quality of life. Spine (Phila Pa 1976). 2016;42(6):411–9.CrossRef Yoshida G, Boissiere L, Larrieu D, Bourghli A, Vital JM, Gille O, Pointillart V, Challier V, Mariey R, Pellise F, et al. Advantages and disadvantages of adult spinal deformity surgery and its impact on health-related quality of life. Spine (Phila Pa 1976). 2016;42(6):411–9.CrossRef
16.
go back to reference Burstrom K, Johannesson M, Diderichsen F. Swedish population health-related quality of life results using the EQ-5D. Qual Life Res. 2001;10(7):621–35.CrossRefPubMed Burstrom K, Johannesson M, Diderichsen F. Swedish population health-related quality of life results using the EQ-5D. Qual Life Res. 2001;10(7):621–35.CrossRefPubMed
17.
go back to reference Danielsson AJ, Romberg K. Reliability and validity of the Swedish version of the Scoliosis Research Society-22 (SRS-22r) patient questionnaire for idiopathic scoliosis. Spine (Phila Pa 1976). 2013;38(21):1875–84.CrossRef Danielsson AJ, Romberg K. Reliability and validity of the Swedish version of the Scoliosis Research Society-22 (SRS-22r) patient questionnaire for idiopathic scoliosis. Spine (Phila Pa 1976). 2013;38(21):1875–84.CrossRef
18.
go back to reference Grauers A, Topalis C, Moller H, Normelli H, Karlsson M, Danielsson A, Gerdhem P. Prevalence of back problems in 1069 adults with idiopathic scoliosis and 158 adults without scoliosis. Spine (Phila Pa 1976). 2014;39(11):886–92.CrossRef Grauers A, Topalis C, Moller H, Normelli H, Karlsson M, Danielsson A, Gerdhem P. Prevalence of back problems in 1069 adults with idiopathic scoliosis and 158 adults without scoliosis. Spine (Phila Pa 1976). 2014;39(11):886–92.CrossRef
19.
go back to reference Diarbakerli E, Grauers A, Gerdhem P. Population-based normative data for the Scoliosis Research Society 22r questionnaire in adolescents and adults, including a comparison with EQ-5D. Eur Spine J. 2016 Epub Nov 11. Diarbakerli E, Grauers A, Gerdhem P. Population-based normative data for the Scoliosis Research Society 22r questionnaire in adolescents and adults, including a comparison with EQ-5D. Eur Spine J. 2016 Epub Nov 11.
20.
go back to reference Lenke LG, Betz RR, Harms J, Bridwell KH, Clements DH, Lowe TG, Blanke K. Adolescent idiopathic scoliosis: a new classification to determine extent of spinal arthrodesis. J Bone Joint Surg Am. 2001;83-A(8):1169–81.CrossRefPubMed Lenke LG, Betz RR, Harms J, Bridwell KH, Clements DH, Lowe TG, Blanke K. Adolescent idiopathic scoliosis: a new classification to determine extent of spinal arthrodesis. J Bone Joint Surg Am. 2001;83-A(8):1169–81.CrossRefPubMed
21.
go back to reference Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39(2):175–91.CrossRefPubMed Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39(2):175–91.CrossRefPubMed
22.
go back to reference Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hoboken: Taylor and Francis; 2013. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hoboken: Taylor and Francis; 2013.
23.
go back to reference Smith JS, Lafage V, Shaffrey CI, Schwab F, Lafage R, Hostin R, O’Brien M, Boachie-Adjei O, Akbarnia BA, Mundis GM, et al. Outcomes of operative and nonoperative treatment for adult spinal deformity: a prospective, multicenter, propensity-matched cohort assessment with minimum 2-year follow-up. Neurosurgery. 2015;78(6):851–61.CrossRef Smith JS, Lafage V, Shaffrey CI, Schwab F, Lafage R, Hostin R, O’Brien M, Boachie-Adjei O, Akbarnia BA, Mundis GM, et al. Outcomes of operative and nonoperative treatment for adult spinal deformity: a prospective, multicenter, propensity-matched cohort assessment with minimum 2-year follow-up. Neurosurgery. 2015;78(6):851–61.CrossRef
24.
go back to reference Glassman SD, Schwab F, Bridwell KH, Shaffrey C, Horton W, Hu S. Do 1-year outcomes predict 2-year outcomes for adult deformity surgery? Spine J. 2009;9(4):317–22.CrossRefPubMed Glassman SD, Schwab F, Bridwell KH, Shaffrey C, Horton W, Hu S. Do 1-year outcomes predict 2-year outcomes for adult deformity surgery? Spine J. 2009;9(4):317–22.CrossRefPubMed
25.
go back to reference Zimmerman RM, Mohamed AS, Skolasky RL, Robinson MD, Kebaish KM. Functional outcomes and complications after primary spinal surgery for scoliosis in adults aged forty years or older: a prospective study with minimum two-year follow-up. Spine (Phila Pa 1976). 2010;35(20):1861–6.CrossRef Zimmerman RM, Mohamed AS, Skolasky RL, Robinson MD, Kebaish KM. Functional outcomes and complications after primary spinal surgery for scoliosis in adults aged forty years or older: a prospective study with minimum two-year follow-up. Spine (Phila Pa 1976). 2010;35(20):1861–6.CrossRef
26.
go back to reference Bridwell KH, Berven S, Glassman S, Hamill C, Horton 3rd WC, Lenke LG, Schwab F, Baldus C, Shainline M. Is the SRS-22 instrument responsive to change in adult scoliosis patients having primary spinal deformity surgery? Spine (Phila Pa 1976). 2007;32(20):2220–5.CrossRef Bridwell KH, Berven S, Glassman S, Hamill C, Horton 3rd WC, Lenke LG, Schwab F, Baldus C, Shainline M. Is the SRS-22 instrument responsive to change in adult scoliosis patients having primary spinal deformity surgery? Spine (Phila Pa 1976). 2007;32(20):2220–5.CrossRef
27.
go back to reference Crawford 3rd CH, Glassman SD, Bridwell KH, Berven SH, Carreon LY. The minimum clinically important difference in SRS-22R total score, appearance, activity and pain domains after surgical treatment of adult spinal deformity. Spine (Phila Pa 1976). 2015;40(6):377–81.CrossRef Crawford 3rd CH, Glassman SD, Bridwell KH, Berven SH, Carreon LY. The minimum clinically important difference in SRS-22R total score, appearance, activity and pain domains after surgical treatment of adult spinal deformity. Spine (Phila Pa 1976). 2015;40(6):377–81.CrossRef
28.
go back to reference Adobor RD, Rimeslatten S, Keller A, Brox JI. Repeatability, reliability, and concurrent validity of the scoliosis research society-22 questionnaire and EuroQol in patients with adolescent idiopathic scoliosis. Spine (Phila Pa 1976). 2010;35(2):206–9.CrossRef Adobor RD, Rimeslatten S, Keller A, Brox JI. Repeatability, reliability, and concurrent validity of the scoliosis research society-22 questionnaire and EuroQol in patients with adolescent idiopathic scoliosis. Spine (Phila Pa 1976). 2010;35(2):206–9.CrossRef
29.
30.
go back to reference Solberg TK, Sorlie A, Sjaavik K, Nygaard OP, Ingebrigtsen T. Would loss to follow-up bias the outcome evaluation of patients operated for degenerative disorders of the lumbar spine? Acta Orthop. 2011;82(1):56–63.CrossRefPubMedPubMedCentral Solberg TK, Sorlie A, Sjaavik K, Nygaard OP, Ingebrigtsen T. Would loss to follow-up bias the outcome evaluation of patients operated for degenerative disorders of the lumbar spine? Acta Orthop. 2011;82(1):56–63.CrossRefPubMedPubMedCentral
Metadata
Title
An observational study on surgically treated adult idiopathic scoliosis patients’ quality of life outcomes at 1- and 2-year follow-ups and comparison to controls
Authors
Jennifer C. Theis
Anna Grauers
Elias Diarbakerli
Panayiotis Savvides
Allan Abbott
Paul Gerdhem
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Scoliosis and Spinal Disorders / Issue 1/2017
Electronic ISSN: 2397-1789
DOI
https://doi.org/10.1186/s13013-017-0118-y

Other articles of this Issue 1/2017

Scoliosis and Spinal Disorders 1/2017 Go to the issue