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Acta Neurologica Belgica
Published in: Acta Neurologica Belgica 6/2020

01-12-2020 | Amyotrophic Lateral Sclerosis | Review article

Kennedy’s disease: an under-recognized motor neuron disorder

Authors: Elia G. Malek, Johnny S. Salameh, Achraf Makki

Published in: Acta Neurologica Belgica | Issue 6/2020

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Abstract

Kennedy’s disease or spinal bulbar muscular atrophy is a rare, inherited and slowly progressive multisystem disease mostly manifesting with a motor neuron disease phenotype leading to disability. The slow progression, partial androgen insensitivity, electrophysiological evidence of sensory neuronopathy, and relatively spared central nervous system pathways help differentiate it from amyotrophic lateral sclerosis. To date, there is no treatment or cure with clinical care mainly focused on accurate diagnosis, symptom management, patient education, and genetic counselling.
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Metadata
Title
Kennedy’s disease: an under-recognized motor neuron disorder
Authors
Elia G. Malek
Johnny S. Salameh
Achraf Makki
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Acta Neurologica Belgica / Issue 6/2020
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-020-01472-6

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