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Published in: BMC Pulmonary Medicine 1/2021

Open Access 01-12-2021 | Amphotericin B | Case report

Isolated pulmonary mucormycosis in an immunocompetent patient: a case report and systematic review of the literature

Authors: Jianhan He, Gaohong Sheng, Huihui Yue, Fengqin Zhang, Hui-Lan Zhang

Published in: BMC Pulmonary Medicine | Issue 1/2021

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Abstract

Background

Pulmonary mucormycosis caused by Mucorales is a highly lethal invasive fungal infection usually found in immunocompromised patients. Isolated pulmonary mucormycosis in immunocompetent patients is very rare. Here, we present a case of a 32-year-old male who developed pulmonary mucormycosis without any known immunodeficiency.

Case presentation

The patient presented to our hospital because of cough and chest pain along with blood in the sputum. He was first treated for community-acquired pneumonia until bronchoalveolar lavage fluid culture confirmed the growth of Absidia. His symptoms were relieved with the use of amphotericin B, and he eventually recovered. We also provide a systematic review of relevant literature to summarize the characteristics of pulmonary mucormycosis in immunocompetent patients.

Conclusions

Pulmonary mucormycosis has variable clinical presentations and is difficult to identify. Due to its high fatality rate, clinicians should make judgements regarding suspected cases correctly and in a timely manner to avoid misdiagnosis and delayed treatment.
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Metadata
Title
Isolated pulmonary mucormycosis in an immunocompetent patient: a case report and systematic review of the literature
Authors
Jianhan He
Gaohong Sheng
Huihui Yue
Fengqin Zhang
Hui-Lan Zhang
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Pulmonary Medicine / Issue 1/2021
Electronic ISSN: 1471-2466
DOI
https://doi.org/10.1186/s12890-021-01504-8

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