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Published in: Diabetes Therapy 12/2020

Open Access 01-12-2020 | Albuminuria | Correction

Correction to: Safety and Efficacy of Exenatide Once Weekly in Participants with Type 2 Diabetes and Stage 2/3 Chronic Kidney Disease

Authors: Cristian Guja, Juan P. Frías, Lisa Suchower, Elise Hardy, Galina Marr, C. David Sjöström, Serge A. Jabbour

Published in: Diabetes Therapy | Issue 12/2020

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Excerpt

In the original article, Table 1 was published with a type-set error. The correct Table 1 is given below.
Table 1
Demographics and baseline characteristics for participants with Type 2 diabetes, by baseline CKD category—8-study pool (intention-to-treat analysis set)
Characteristic
CKD3
CKD2
EQW
N = 182
All comparators
N = 207
EQW
N = 772
All comparators
N = 1043
Men, n (%)
105 (57.7)
105 (50.7)
419 (54.3)
608 (58.3)
Age (years), mean (SD)
62.5 (9.0)
62.2 (9.0)
56.9 (9.3)
56.9 (9.5)
Age < 65 years, n(%)
102 (56.0)
120 (58.0)
613 (79.4)
820 (78.6)
Race, White, n (%)
66 (36.3)
89 (43.0)
522 (67.6)
685 (65.7)
Race, Asian, n (%)
111 (61.0)
106 (51.2)
157 (20.3)
227 (21.8)
Race, Black or African American, n (%)
0
5 (2.4)
38 (4.9)
39 (3.7)
Body weight (kg), mean (SD)
76.9 (19.3)
78.5 (17.7)
88.8 (19.3)a
87.8 (19.1)
BMI (kg/m2), mean (SD)
28.3 (5.1)
29.6 (5.8)
31.6 (5.5)a
31.4 (5.6)
BMI ≥ 35 (kg/m2), n (%)
24 (13.2)
40 (19.3)
196 (25.4)
246 (23.6)
Sitting SBP (mm Hg), mean (SD)
133 (14.3)
136 (17.2)
131 (13.8)
131 (14.6)
Sitting DBP (mm Hg), mean (SD)
77 (9.7)
79 (9.6)
79 (9.3)
79 (8.8)
eGFR (mL/min/1.73 m2), mean (SD)
52.7 (5.6)
53.3 (5.1)
75.9 (8.4)
75.9 (8.6)
uACR (mg/g), mean (SD), median
105 (348), 14.2
(n = 151)
116 (438), 20.4
(n = 165)
54.1 (171), 10.6
(n = 528)
47.9 (158), 10.6
(n = 810)
  < 30 mg/g (normal), n (%)
96 (52.7)
108 (52.2)
398 (51.6)
609 (58.4)
  ≥ 30 to ≤ 300 mg/g (moderately increased albuminuria), n (%)
45 (24.7)
46 (22.2)
108 (14.0)
178 (17.1)
  > 300 mg/g (severely increased albuminuria), n (%)
10 (5.5)
11 (5.3)
22 (2.8)
23 (2.2)
 Unknownb, n (%)
31 (17.0)
42 (20.3)
244 (31.6)
233 (22.3)
Duration of T2D (years), mean (SD)
9.7 (6.8)
9.5 (6.8)
7.6 (6.3)a
6.3 (5.5)a
HbA1c (%), mean (SD)
8.3 (0.8)
8.5 (0.9)
8.5 (1.1)
8.4 (1.1)
FPG (mg/dL), mean (SD)
168 (46.7)
(n = 181)
176 (50.2)
(n = 203)
172 (50.0)
(n = 751)
171 (46.8)
(n = 1026)
Baseline anti-hyperglycaemic drugsc
       
 None, n (%)
8 (4.4)
34 (16.4)
135 (17.5)
299 (28.7)
 Metformin, n (%)
155 (85.2)
159 (72.5)
529 (68.5)
647 (62.0)
 Sulfonylureas, n (%)
4 (2.2)
10 (4.8)
55 (7.1)
55 (5.3)
 Thiazolidinediones, n (%)
36 (19.8)
31 (15.0)
32 (4.1)
39 (3.7)
 Insulin, n (%)
18 (9.9)
22 (10.6)
107 (13.9)
98 (9.4)
BMI body mass index, CKD chronic kidney disease, CKD2 stage 2 CKD, CKD3 stage 3 CKD, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, EQW exenatide once weekly, FPG fasting plasma glucose, HbA1c glycated haemoglobin, N number of participants in the pooled treatment group, n number of participants in analysis, SBP systolic blood pressure, SD standard deviation, T2D type 2 diabetes, uACR urinary albumin-to-creatinine ratio
aOne participant had no result
buACR was not collected in two studies (DURATION-7 and DURATION-8)
cOne additional participant took repaglinide (EQW, CKD2), which was not a permitted background anti-hyperglycaemic drug per the protocol
Metadata
Title
Correction to: Safety and Efficacy of Exenatide Once Weekly in Participants with Type 2 Diabetes and Stage 2/3 Chronic Kidney Disease
Authors
Cristian Guja
Juan P. Frías
Lisa Suchower
Elise Hardy
Galina Marr
C. David Sjöström
Serge A. Jabbour
Publication date
01-12-2020
Publisher
Springer Healthcare
Published in
Diabetes Therapy / Issue 12/2020
Print ISSN: 1869-6953
Electronic ISSN: 1869-6961
DOI
https://doi.org/10.1007/s13300-020-00842-w

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