Issue 3/2019
Content (11 Articles)
Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies
Paul A. De Sousa, Diane Ritchie, Alison Green, Siddharthan Chandran, Richard Knight, Mark W. Head
Retinal α-synuclein deposits in Parkinson’s disease patients and animal models
Lien Veys, Marjan Vandenabeele, Isabel Ortuño-Lizarán, Veerle Baekelandt, Nicolás Cuenca, Lieve Moons, Lies De Groef
Amyloid-β pathology enhances pathological fibrillary tau seeding induced by Alzheimer PHF in vivo
Cristina Vergara, Sarah Houben, Valérie Suain, Zehra Yilmaz, Robert De Decker, Virginie Vanden Dries, Alain Boom, Salwa Mansour, Karelle Leroy, Kunie Ando, Jean-Pierre Brion
Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia
Sylvia E. Perez, Jennifer C. Miguel, Bin He, Michael Malek-Ahmadi, Eric E. Abrahamson, Milos D. Ikonomovic, Ira Lott, Eric Doran, Melissa J. Alldred, Stephen D. Ginsberg, Elliott J. Mufson
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines
Amanda L. Woerman, Abby Oehler, Sabeen A. Kazmi, Jisoo Lee, Glenda M. Halliday, Lefkos T. Middleton, Steve M. Gentleman, Daniel A. Mordes, Salvatore Spina, Lea T. Grinberg, Steven H. Olson, Stanley B. Prusiner
Wide distribution of alpha-synuclein oligomers in multiple system atrophy brain detected by proximity ligation
Hiroaki Sekiya, Hisatomo Kowa, Hinako Koga, Mariko Takata, Wataru Satake, Naonobu Futamura, Itaru Funakawa, Kenji Jinnai, Motonori Takahashi, Takeshi Kondo, Yasuhiro Ueno, Motoi Kanagawa, Kazuhiro Kobayashi, Tatsushi Toda
Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat
Sophie Hillebrand, Kathrin Schanda, Magdalini Nigritinou, Irina Tsymala, Denise Böhm, Patrick Peschl, Yoshiki Takai, Kazuo Fujihara, Ichiro Nakashima, Tatsuro Misu, Markus Reindl, Hans Lassmann, Monika Bradl
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
Thomas G. Moens, Teresa Niccoli, Katherine M. Wilson, Magda L. Atilano, Nicol Birsa, Lauren M. Gittings, Benedikt V. Holbling, Miranda C. Dyson, Annora Thoeng, Jacob Neeves, Idoia Glaria, Lu Yu, Julia Bussmann, Erik Storkebaum, Mercedes Pardo, Jyoti S. Choudhary, Pietro Fratta, Linda Partridge, Adrian M. Isaacs
ACTN2 mutations cause “Multiple structured Core Disease” (MsCD)
Xavière Lornage, Norma B. Romero, Claire A. Grosgogeat, Edoardo Malfatti, Sandra Donkervoort, Michael M. Marchetti, Sarah B. Neuhaus, A. Reghan Foley, Clémence Labasse, Raphaël Schneider, Robert Y. Carlier, Katherine R. Chao, Livija Medne, Jean-François Deleuze, David Orlikowski, Carsten G. Bönnemann, Vandana A. Gupta, Michel Fardeau, Johann Böhm, Jocelyn Laporte
Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1
Julieann C. Lee, Javier E. Villanueva-Meyer, Sean P. Ferris, Emily A. Sloan, Jeffrey W. Hofmann, Eyas M. Hattab, Brian J. Williams, Hua Guo, Joseph Torkildson, Adriana Florez, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Soo-Jin Cho, Andrew E. Horvai, David T. W. Jones, Stefan M. Pfister, Christian Koelsche, Andreas von Deimling, Andrey Korshunov, Arie Perry, David A. Solomon
Antisense RNA foci are associated with nucleoli and TDP-43 mislocalization in C9orf72-ALS/FTD: a quantitative study
Olubankole Aladesuyi Arogundade, Jennifer E. Stauffer, Shahram Saberi, Sandra Diaz-Garcia, Sahana Malik, Hani Basilim, Maria J. Rodriguez, Takuya Ohkubo, John Ravits