Published in:
01-08-2008 | Correspondence
Acetylcholinesterase Inhibitors May Improve Efficacy and Reduce Adverse Effects of Tricyclic Antidepressants for Depression
Author:
Helmut Niederhofer
Published in:
Drugs & Aging
|
Issue 8/2008
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Excerpt
Passmore et al.[
1] report that acetylcholinesterase inhibitors, antiepileptics, lithium, anxiolytics, analgesics, β-adrenoceptor antagonists, cannabinoid receptor agonists and hormonal agents may be effective in treating dementia-related agitation. Figiel and Sadowski[
2] report that the cholinergic system appears to be involved in different behaviours and disorders, including depression. Acetylcholinesterase inhibitors have been developed for the treatment of dementia, in which setting they enhance acetylcholine levels and have neuroprotective functions.[
3] …