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Archives of Gynecology and Obstetrics

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01-05-2015 | General Gynecology

Accuracy of endometrial sampling compared to conventional dilatation and curettage in women with abnormal uterine bleeding

Authors: Ibrahim A. Abdelazim, Khaled M. Abdelrazak, Assem A. M. Elbiaa, Mohamed Al-Kadi, Amr H. Yehia

Published in: Archives of Gynecology and Obstetrics | Issue 5/2015

Abstract

Objectives

To compare the diagnostic accuracy of brush endometrial sampling with conventional dilatation and curettage in women with abnormal uterine bleeding.

Patients and methods

Two hundred and twenty (220) women with abnormal uterine bleeding were included in this comparative study; endometrial sampling was done before cervical dilatation using Tao Bruch followed by conventional dilatation and curettage (D&C). The histopathology report of the Tao Bruch samples was compared with that of the D&C samples and the D&C results were considered as the gold standard.

Results

100 % of samples obtained by conventional D&C, while 98.2 % of the samples obtained by Tao Brush were adequate for histopathology examination. In this study; Tao Brush had 100 % sensitivity, 100 % specificity, 100 % predictive values and accuracy for diagnosing endometrial hyperplasia, endometrial carcinoma, proliferative and secretory endometrium, also, it had 86.7 % sensitivity, 100 % specificity, 100 % positive predictive value (PPV) and 99 % negative predictive value (NPV) and accuracy for diagnosing endometritis (no significant difference compared to conventional D&C), while, it had 77.8 % sensitivity, 100 % specificity, 100 % PPV and 99 % NPV and accuracy for diagnosing endometrial polyps (no significant difference compared to conventional D&C)

Conclusion

Endometrial sampling using endometrial brush cytology (EBC) is safe, accurate, cost-effective outpatient procedure, avoids general anesthesia with high sensitivity and specificity for detection of endometrial hyperplasia and endometrial carcinoma. EBC could be used as complementary diagnostic tool when hysteroscopic biopsies or other blinded procedures for endometrial sampling are unwanted or not available.

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Title: Accuracy of endometrial sampling compared to conventional dilatation and curettage in women with abnormal uterine bleeding
Authors: Ibrahim A. Abdelazim
Khaled M. Abdelrazak
Assem A. M. Elbiaa
Mohamed Al-Kadi
Amr H. Yehia
Publication date: 01-05-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 5/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-014-3523-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Accuracy of endometrial sampling compared to conventional dilatation and curettage in women with abnormal uterine bleeding

Abstract

Objectives

Patients and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Patients and methods

Results

Conclusion

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