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Forensic Toxicology
Published in: Forensic Toxicology 2/2016

01-07-2016 | Original Article

Absolute configuration of the synthetic cannabinoid MDMB-CHMICA with its chemical characteristics in illegal products

Authors: Lars Andernach, Stefan Pusch, Carina Weber, Dieter Schollmeyer, Sascha Münster-Müller, Michael Pütz, Till Opatz

Published in: Forensic Toxicology | Issue 2/2016

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Abstract

A seized sample of the synthetic cannabinoid MDMB-CHMICA was studied by means of vibrational and electronic circular dichroism spectroscopy and found to have (S)-configuration by comparison of the experimental spectra with density functional theory calculations. We were able to additionally confirm the absolute configuration was additionally confirmed using X-ray crystallography. Furthermore, the title compound was extracted from five commercially available “Spice-like” herbal mixtures. The extracts were all found to have the same absolute configuration as the seized sample and all analyzed samples were found to be of very high optical purity as judged by chiral high-performance liquid chromatography.
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Metadata
Title
Absolute configuration of the synthetic cannabinoid MDMB-CHMICA with its chemical characteristics in illegal products
Authors
Lars Andernach
Stefan Pusch
Carina Weber
Dieter Schollmeyer
Sascha Münster-Müller
Michael Pütz
Till Opatz
Publication date
01-07-2016
Publisher
Springer Japan
Published in
Forensic Toxicology / Issue 2/2016
Print ISSN: 1860-8965
Electronic ISSN: 1860-8973
DOI
https://doi.org/10.1007/s11419-016-0321-1

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