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Published in: Journal of Translational Medicine 1/2012

Open Access 01-12-2012 | Review

A road map to Translational Medicine in Qatar and a model for the world

Authors: Francesco M Marincola, Javaid I Sheikh

Published in: Journal of Translational Medicine | Issue 1/2012

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Abstract

Translational Medicine (TM) in Qatar is part of a concerted effort of the Qatari medical and scientific leadership supported by a strong political will by Qatari authorities to deliver world-class health care to Qatari residents while participating in the worldwide quest to bridge the gap between bench-to-bedside-to-community. TM programs should embrace the Qatar National vision for research to become an international hub of excellence in research and development, based on intellectual merit, contributing to global knowledge and adhering to international standards, to innovate by translating new and original ideas into useful applications, to be inclusive at the national and international level, to build and maintain a competitive and diversified economy and ultimately improve the health and well-being of the Qatar’s population. Although this writing focuses on Qatar, we hope that the thoughts expressed here may be of broader use for the development of any TM program particularly in regions where an established academic community surrounded by a rich research infrastructure and/or a vibrant biotechnology enterprise is not already present.
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Literature
1.
go back to reference Lindahl S, Marincola FM: Translational medicine. Encyclopedia Britannica. 2012, 2012: 2012-in press Lindahl S, Marincola FM: Translational medicine. Encyclopedia Britannica. 2012, 2012: 2012-in press
3.
go back to reference Mankoff SP, Brander C, Ferrone S, Marincola FM: Lost in translation: obstacles to Translational Medicine. J Transl Med. 2004, 2: 14-10.1186/1479-5876-2-14.CrossRefPubMedPubMedCentral Mankoff SP, Brander C, Ferrone S, Marincola FM: Lost in translation: obstacles to Translational Medicine. J Transl Med. 2004, 2: 14-10.1186/1479-5876-2-14.CrossRefPubMedPubMedCentral
4.
go back to reference Chouchane L, Mamtani R, Al-Thani MH, Al-Thani AA, Ameduri M, Sheikh JI: Medical education and research environment in Qatar: a new epoch for translational research in the Middle East. J Transl Med. 2011, 9: 16-10.1186/1479-5876-9-16.CrossRefPubMedPubMedCentral Chouchane L, Mamtani R, Al-Thani MH, Al-Thani AA, Ameduri M, Sheikh JI: Medical education and research environment in Qatar: a new epoch for translational research in the Middle East. J Transl Med. 2011, 9: 16-10.1186/1479-5876-9-16.CrossRefPubMedPubMedCentral
5.
go back to reference Moore CG, Carter RE, Nietert PJ, Stewart PW: Recommendations for planning pilot studies in clinical and translational research. Clin Transl Sci. 2011, 4: 332-337. 10.1111/j.1752-8062.2011.00347.x.CrossRefPubMedPubMedCentral Moore CG, Carter RE, Nietert PJ, Stewart PW: Recommendations for planning pilot studies in clinical and translational research. Clin Transl Sci. 2011, 4: 332-337. 10.1111/j.1752-8062.2011.00347.x.CrossRefPubMedPubMedCentral
6.
go back to reference Horig H, Marincola E, Marincola FM: Obstacles and opportunities in translational research. Nat Med. 2005, 11: 705-708. 10.1038/nm0705-705.CrossRefPubMed Horig H, Marincola E, Marincola FM: Obstacles and opportunities in translational research. Nat Med. 2005, 11: 705-708. 10.1038/nm0705-705.CrossRefPubMed
7.
go back to reference Littman BH, Di Mario L, Plebani M, Marincola FM: What's next in Translational Medicine?. Clin Sci (Lond). 2007, 112: 217-227. 10.1042/CS20060108.CrossRef Littman BH, Di Mario L, Plebani M, Marincola FM: What's next in Translational Medicine?. Clin Sci (Lond). 2007, 112: 217-227. 10.1042/CS20060108.CrossRef
8.
go back to reference Marincola FM: The trouble with translational medicine. J Intern Med. 2011, 270: 123-127. 10.1111/j.1365-2796.2011.02402.x.CrossRefPubMed Marincola FM: The trouble with translational medicine. J Intern Med. 2011, 270: 123-127. 10.1111/j.1365-2796.2011.02402.x.CrossRefPubMed
11.
go back to reference Galon J, Pages F, Marincola FM, Thurin M, Trinchieri G, Fox BA, Gajewski TF, Ascierto PA: The Immune Score as a New Possible Approach for the Classification of Cancer. J Transl Med. 2012, 10: 1-10.1186/1479-5876-10-1.CrossRefPubMedPubMedCentral Galon J, Pages F, Marincola FM, Thurin M, Trinchieri G, Fox BA, Gajewski TF, Ascierto PA: The Immune Score as a New Possible Approach for the Classification of Cancer. J Transl Med. 2012, 10: 1-10.1186/1479-5876-10-1.CrossRefPubMedPubMedCentral
14.
go back to reference Emens LA, Silverstein SC, Khleif S, Marincola FM, Galon J: Toward integrative cancer immunotherapy: targeting the tumor microenvironment. J Transl Med. 2012, 10: 70-10.1186/1479-5876-10-70.CrossRefPubMedPubMedCentral Emens LA, Silverstein SC, Khleif S, Marincola FM, Galon J: Toward integrative cancer immunotherapy: targeting the tumor microenvironment. J Transl Med. 2012, 10: 70-10.1186/1479-5876-10-70.CrossRefPubMedPubMedCentral
16.
go back to reference Stroncek DF, Berger C, Cheever MA, Childs RW, Dudley ME, Flynn P, Gattinoni L, Heath JR, Kalos M, Marincola FM: New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer. J Transl Med. 2012, 10: 48-10.1186/1479-5876-10-48.CrossRefPubMedPubMedCentral Stroncek DF, Berger C, Cheever MA, Childs RW, Dudley ME, Flynn P, Gattinoni L, Heath JR, Kalos M, Marincola FM: New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer. J Transl Med. 2012, 10: 48-10.1186/1479-5876-10-48.CrossRefPubMedPubMedCentral
17.
go back to reference van der Burg SH, Melief CJ: Therapeutic vaccination against human papilloma virus induced malignancies. Curr Opin Immunol. 2011, 23: 252-257. 10.1016/j.coi.2010.12.010.CrossRefPubMed van der Burg SH, Melief CJ: Therapeutic vaccination against human papilloma virus induced malignancies. Curr Opin Immunol. 2011, 23: 252-257. 10.1016/j.coi.2010.12.010.CrossRefPubMed
18.
go back to reference Kenter GG, Welters MJ, Valentijn AR, Lowik MJ, Berends-van der Meer DM, Vloon AP, Essahsah F, Fathers LM, Offringa R, Drijfhout JW: Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med. 2009, 361: 1838-1847. 10.1056/NEJMoa0810097.CrossRefPubMed Kenter GG, Welters MJ, Valentijn AR, Lowik MJ, Berends-van der Meer DM, Vloon AP, Essahsah F, Fathers LM, Offringa R, Drijfhout JW: Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med. 2009, 361: 1838-1847. 10.1056/NEJMoa0810097.CrossRefPubMed
19.
go back to reference Brichard VG, Lejeune D: Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease. Expert Opin Biol Ther. 2008, 8: 951-968. 10.1517/14712598.8.7.951.CrossRefPubMed Brichard VG, Lejeune D: Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease. Expert Opin Biol Ther. 2008, 8: 951-968. 10.1517/14712598.8.7.951.CrossRefPubMed
20.
go back to reference Sonnett TE, Levien TL, Gates BJ, Robinson JD, Campbell RK: Diabetes mellitus, inflammation, obesity: proposed treatment pathways for current and future therapies. Ann Pharmacother. 2010, 44: 701-711. 10.1345/aph.1M640.CrossRefPubMed Sonnett TE, Levien TL, Gates BJ, Robinson JD, Campbell RK: Diabetes mellitus, inflammation, obesity: proposed treatment pathways for current and future therapies. Ann Pharmacother. 2010, 44: 701-711. 10.1345/aph.1M640.CrossRefPubMed
21.
go back to reference Robinson GA, Geier M, Rizzolo D, Sedrak M: Childhood obesity: complications, prevention strategies, treatment. JAAPA. 2011, 24: 58-63.PubMed Robinson GA, Geier M, Rizzolo D, Sedrak M: Childhood obesity: complications, prevention strategies, treatment. JAAPA. 2011, 24: 58-63.PubMed
22.
go back to reference Peterlik M: Vitamin D insufficiency and chronic diseases: Hype and reality. Food Funct. 2012, 3: 784-794. 10.1039/c2fo10262e.CrossRefPubMed Peterlik M: Vitamin D insufficiency and chronic diseases: Hype and reality. Food Funct. 2012, 3: 784-794. 10.1039/c2fo10262e.CrossRefPubMed
23.
go back to reference Hatse S, Lambrechts D, Verstuyf A, Smeets A, Brouwers B, Vandorpe T, Brouckaert O, Peuteman G, Laenen A, Verlinden L: Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome and genetic determinants of vitamin D insufficiency. Carcinogenesis. 2012, 33: 1319-1326. 10.1093/carcin/bgs187.CrossRefPubMed Hatse S, Lambrechts D, Verstuyf A, Smeets A, Brouwers B, Vandorpe T, Brouckaert O, Peuteman G, Laenen A, Verlinden L: Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome and genetic determinants of vitamin D insufficiency. Carcinogenesis. 2012, 33: 1319-1326. 10.1093/carcin/bgs187.CrossRefPubMed
24.
go back to reference Laleye LC, Kerkadi AH, Wasesa AA, Rao MV, Aboubacar A: Assessment of vitamin D and vitamin A intake by female students at the United Arab Emirates University based on self-reported dietary and selected fortified food consumption. Int J Food Sci Nutr. 2011, 62: 370-376. 10.3109/09637486.2010.533159.CrossRefPubMed Laleye LC, Kerkadi AH, Wasesa AA, Rao MV, Aboubacar A: Assessment of vitamin D and vitamin A intake by female students at the United Arab Emirates University based on self-reported dietary and selected fortified food consumption. Int J Food Sci Nutr. 2011, 62: 370-376. 10.3109/09637486.2010.533159.CrossRefPubMed
27.
go back to reference Bittles AH, Black ML: Evolution in health and medicine Sackler colloquium: Consanguinity, human evolution, and complex diseases. Proc Natl Acad Sci U S A. 2010, 107 (Suppl 1): 1779-1786.CrossRefPubMedPubMedCentral Bittles AH, Black ML: Evolution in health and medicine Sackler colloquium: Consanguinity, human evolution, and complex diseases. Proc Natl Acad Sci U S A. 2010, 107 (Suppl 1): 1779-1786.CrossRefPubMedPubMedCentral
28.
go back to reference Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010, 42: 105-116. 10.1038/ng.520.CrossRefPubMedPubMedCentral Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010, 42: 105-116. 10.1038/ng.520.CrossRefPubMedPubMedCentral
29.
go back to reference Lyssenko V, Almgren P, Anevski D, Orho-Melander M, Sjogren M, Saloranta C, Tuomi T, Groop L: Genetic prediction of future type 2 diabetes. PLoS Med. 2005, 2: e345-10.1371/journal.pmed.0020345.CrossRefPubMedPubMedCentral Lyssenko V, Almgren P, Anevski D, Orho-Melander M, Sjogren M, Saloranta C, Tuomi T, Groop L: Genetic prediction of future type 2 diabetes. PLoS Med. 2005, 2: e345-10.1371/journal.pmed.0020345.CrossRefPubMedPubMedCentral
30.
go back to reference Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010, 42: 579-589. 10.1038/ng.609.CrossRefPubMedPubMedCentral Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010, 42: 579-589. 10.1038/ng.609.CrossRefPubMedPubMedCentral
31.
go back to reference Liede A, Malik IA, Aziz Z, Rios Pd PL, Kwan E, Narod SA: Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan. Am J Hum Genet. 2002, 71: 595-606. 10.1086/342506.CrossRefPubMedPubMedCentral Liede A, Malik IA, Aziz Z, Rios Pd PL, Kwan E, Narod SA: Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan. Am J Hum Genet. 2002, 71: 595-606. 10.1086/342506.CrossRefPubMedPubMedCentral
32.
go back to reference Ismail J, Jafar TH, Jafary FH, White F, Faruqui AM, Chaturvedi N: Risk factors for non-fatal myocardial infarction in young South Asian adults. Heart. 2004, 90: 259-263. 10.1136/hrt.2003.013631.CrossRefPubMedPubMedCentral Ismail J, Jafar TH, Jafary FH, White F, Faruqui AM, Chaturvedi N: Risk factors for non-fatal myocardial infarction in young South Asian adults. Heart. 2004, 90: 259-263. 10.1136/hrt.2003.013631.CrossRefPubMedPubMedCentral
33.
go back to reference Ley TJ, Rosenberg LE: Removing career obstacles for young physician-scientists – loan-repayment programs. N Engl J Med. 2002, 346: 368-372.CrossRefPubMed Ley TJ, Rosenberg LE: Removing career obstacles for young physician-scientists – loan-repayment programs. N Engl J Med. 2002, 346: 368-372.CrossRefPubMed
34.
go back to reference Ley TJ, Rosenberg LE: The physician-scientist career pipeline in 2005: build it, and they will come. JAMA. 2005, 294: 1343-1351. 10.1001/jama.294.11.1343.CrossRefPubMed Ley TJ, Rosenberg LE: The physician-scientist career pipeline in 2005: build it, and they will come. JAMA. 2005, 294: 1343-1351. 10.1001/jama.294.11.1343.CrossRefPubMed
35.
go back to reference Hobin JA, Deschamps AM, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U: Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles. J Transl Med. 2012, 10: 72-10.1186/1479-5876-10-72.CrossRefPubMedPubMedCentral Hobin JA, Deschamps AM, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U: Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles. J Transl Med. 2012, 10: 72-10.1186/1479-5876-10-72.CrossRefPubMedPubMedCentral
38.
go back to reference Friedman TL: The World is flat. 2005, Farrar, Straus & Giroux, New York, NY Friedman TL: The World is flat. 2005, Farrar, Straus & Giroux, New York, NY
39.
go back to reference Morris ZS, Wooding S, Grant J: The answer is 17 years, what is the question: understanding time lags in translational research. J R Soc Med. 2011, 104: 510-520. 10.1258/jrsm.2011.110180.CrossRefPubMedPubMedCentral Morris ZS, Wooding S, Grant J: The answer is 17 years, what is the question: understanding time lags in translational research. J R Soc Med. 2011, 104: 510-520. 10.1258/jrsm.2011.110180.CrossRefPubMedPubMedCentral
42.
go back to reference Fontanarosa PB, DeAngelis CD: Basic science and translational research in JAMA. JAMA. 2002, 287: 1728-10.1001/jama.287.13.1728.CrossRefPubMed Fontanarosa PB, DeAngelis CD: Basic science and translational research in JAMA. JAMA. 2002, 287: 1728-10.1001/jama.287.13.1728.CrossRefPubMed
43.
go back to reference Sung NS, Crowley WF, Genel M, Salber P, Sandy L, Sherwood LM, Johnson SB, Catanese V, Tilson H, Getz K: Central challenges facing the national clinical research enterprise. JAMA. 2003, 289: 1278-1287. 10.1001/jama.289.10.1278.CrossRefPubMed Sung NS, Crowley WF, Genel M, Salber P, Sandy L, Sherwood LM, Johnson SB, Catanese V, Tilson H, Getz K: Central challenges facing the national clinical research enterprise. JAMA. 2003, 289: 1278-1287. 10.1001/jama.289.10.1278.CrossRefPubMed
44.
go back to reference Fontanarosa PB, DeAngelis CD: Translational medical research. JAMA. 2003, 289: 2133-10.1001/jama.289.16.2133.PubMed Fontanarosa PB, DeAngelis CD: Translational medical research. JAMA. 2003, 289: 2133-10.1001/jama.289.16.2133.PubMed
45.
go back to reference Crowley WF, Sherwood L, Salber P, Scheinberg D, Slavkin H, Tilson H, Reece EA, Catanese V, Johnson SB, Dobs A: Clinical research in the United States at a crossroads: proposal for a novel public-private partnership to establish a national clinical research enterprise. JAMA. 2004, 291: 1120-1126. 10.1001/jama.291.9.1120.CrossRefPubMed Crowley WF, Sherwood L, Salber P, Scheinberg D, Slavkin H, Tilson H, Reece EA, Catanese V, Johnson SB, Dobs A: Clinical research in the United States at a crossroads: proposal for a novel public-private partnership to establish a national clinical research enterprise. JAMA. 2004, 291: 1120-1126. 10.1001/jama.291.9.1120.CrossRefPubMed
46.
go back to reference Ioannidis JP: Materializing research promises: opportunities, priorities and conflicts in translational medicine. J Transl Med. 2004, 2: 5-10.1186/1479-5876-2-5.CrossRefPubMedPubMedCentral Ioannidis JP: Materializing research promises: opportunities, priorities and conflicts in translational medicine. J Transl Med. 2004, 2: 5-10.1186/1479-5876-2-5.CrossRefPubMedPubMedCentral
48.
go back to reference Schechter AN, Perlman RL, Rettig RA: Editors' Introduction: Why is Revitalizing Clinical Research So Important, Yet So Difficult?. Perspect Biol Med. 2004, 47: 476-486. 10.1353/pbm.2004.0070.CrossRefPubMed Schechter AN, Perlman RL, Rettig RA: Editors' Introduction: Why is Revitalizing Clinical Research So Important, Yet So Difficult?. Perspect Biol Med. 2004, 47: 476-486. 10.1353/pbm.2004.0070.CrossRefPubMed
49.
go back to reference Snyderman R: The clinical researcher–an "emerging" species. JAMA. 2004, 291: 882-883. 10.1001/jama.291.7.882.CrossRefPubMed Snyderman R: The clinical researcher–an "emerging" species. JAMA. 2004, 291: 882-883. 10.1001/jama.291.7.882.CrossRefPubMed
51.
52.
go back to reference Cech TR: Fostering innovation and discovery in biomedical research. JAMA. 2005, 294: 1390-1393. 10.1001/jama.294.11.1390.CrossRefPubMed Cech TR: Fostering innovation and discovery in biomedical research. JAMA. 2005, 294: 1390-1393. 10.1001/jama.294.11.1390.CrossRefPubMed
53.
go back to reference Cohen JJ, Siegel EK: Academic medical centers and medical research: the challenges ahead. JAMA. 2005, 294: 1367-1372. 10.1001/jama.294.11.1367.CrossRefPubMed Cohen JJ, Siegel EK: Academic medical centers and medical research: the challenges ahead. JAMA. 2005, 294: 1367-1372. 10.1001/jama.294.11.1367.CrossRefPubMed
54.
go back to reference Fontanarosa PB, DeAngelis CD, Hunt N: Medical research–state of the science. JAMA. 2005, 294: 1424-1425. 10.1001/jama.294.11.1424.CrossRefPubMed Fontanarosa PB, DeAngelis CD, Hunt N: Medical research–state of the science. JAMA. 2005, 294: 1424-1425. 10.1001/jama.294.11.1424.CrossRefPubMed
55.
go back to reference Moses H, Dorsey ER, Matheson DH, Thier SO: Financial anatomy of biomedical research. JAMA. 2005, 294: 1333-1342. 10.1001/jama.294.11.1333.CrossRefPubMed Moses H, Dorsey ER, Matheson DH, Thier SO: Financial anatomy of biomedical research. JAMA. 2005, 294: 1333-1342. 10.1001/jama.294.11.1333.CrossRefPubMed
56.
go back to reference Moskowitz J: A not so modest proposal for sustaining the american clinical research enterprise. J Surg Res. 2005, 125: 117-120. 10.1016/j.jss.2005.02.014.CrossRefPubMed Moskowitz J: A not so modest proposal for sustaining the american clinical research enterprise. J Surg Res. 2005, 125: 117-120. 10.1016/j.jss.2005.02.014.CrossRefPubMed
57.
go back to reference Zerhouni EA: US biomedical research: basic, translational, and clinical sciences. JAMA. 2005, 294: 1352-1358. 10.1001/jama.294.11.1352.CrossRefPubMed Zerhouni EA: US biomedical research: basic, translational, and clinical sciences. JAMA. 2005, 294: 1352-1358. 10.1001/jama.294.11.1352.CrossRefPubMed
59.
go back to reference Albani S, Prakken B: The advancement of translational medicine-from regional challenges to global solutions. Nat Med. 2009, 15: 1006-1009. 10.1038/nm0909-1006.CrossRefPubMed Albani S, Prakken B: The advancement of translational medicine-from regional challenges to global solutions. Nat Med. 2009, 15: 1006-1009. 10.1038/nm0909-1006.CrossRefPubMed
60.
go back to reference Collins F: The bridge between lab and clinic. Interview by Meredith Wadman. Nature. 2010, 468: 877-10.1038/468877a.CrossRefPubMed Collins F: The bridge between lab and clinic. Interview by Meredith Wadman. Nature. 2010, 468: 877-10.1038/468877a.CrossRefPubMed
61.
go back to reference Fang FC, Casadevall A: Lost in translation–basic science in the era of translational research. Infect Immun. 2010, 78: 563-566. 10.1128/IAI.01318-09.CrossRefPubMedPubMedCentral Fang FC, Casadevall A: Lost in translation–basic science in the era of translational research. Infect Immun. 2010, 78: 563-566. 10.1128/IAI.01318-09.CrossRefPubMedPubMedCentral
63.
go back to reference Collins FS: Reengineering translational science: the time is right. Sci Transl Med. 2011, 3: 90-cm17CrossRef Collins FS: Reengineering translational science: the time is right. Sci Transl Med. 2011, 3: 90-cm17CrossRef
64.
go back to reference Drolet BC, Lorenzi NM: Translational research: understanding the continuum from bench to bedside. Transl Res. 2011, 157: 1-5. 10.1016/j.trsl.2010.10.002.CrossRefPubMed Drolet BC, Lorenzi NM: Translational research: understanding the continuum from bench to bedside. Transl Res. 2011, 157: 1-5. 10.1016/j.trsl.2010.10.002.CrossRefPubMed
65.
go back to reference Sade RM: From laboratory to bedside: ethical, legal and social issues in translational research. Am J Med Sci. 2011, 342: 265-266. 10.1097/MAJ.0b013e318227deb1.CrossRefPubMedPubMedCentral Sade RM: From laboratory to bedside: ethical, legal and social issues in translational research. Am J Med Sci. 2011, 342: 265-266. 10.1097/MAJ.0b013e318227deb1.CrossRefPubMedPubMedCentral
66.
go back to reference Mintzberg H: Organizational design, fashion or fit?. Harvard Business Rev. 1981, 59: 103-116. Mintzberg H: Organizational design, fashion or fit?. Harvard Business Rev. 1981, 59: 103-116.
67.
69.
go back to reference Carter RE, Woolson RF: Statistical design considerations for pilot studies transitioning therapies from the bench to the bedside. J Transl Med. 2004, 2: 37-10.1186/1479-5876-2-37.CrossRefPubMedPubMedCentral Carter RE, Woolson RF: Statistical design considerations for pilot studies transitioning therapies from the bench to the bedside. J Transl Med. 2004, 2: 37-10.1186/1479-5876-2-37.CrossRefPubMedPubMedCentral
70.
go back to reference Belardelli F, Rizza P, Moretti F, Carella C, Galli MC, Migliaccio G: Translational research on advanced therapies. Ann Ist Super Sanita. 2011, 47: 72-78.PubMed Belardelli F, Rizza P, Moretti F, Carella C, Galli MC, Migliaccio G: Translational research on advanced therapies. Ann Ist Super Sanita. 2011, 47: 72-78.PubMed
71.
go back to reference Fasolo A, Sessa C: Translational research in phase I trials. Clin Transl Oncol. 2009, 11: 580-588. 10.1007/s12094-009-0408-9.CrossRefPubMed Fasolo A, Sessa C: Translational research in phase I trials. Clin Transl Oncol. 2009, 11: 580-588. 10.1007/s12094-009-0408-9.CrossRefPubMed
Metadata
Title
A road map to Translational Medicine in Qatar and a model for the world
Authors
Francesco M Marincola
Javaid I Sheikh
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue 1/2012
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-10-177

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