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Annals of Hematology
Published in: Annals of Hematology 7/2011

01-07-2011 | Letter to the Editor

A novel point mutation within the juxtamembrane domain of the flt3 gene in acute myeloid leukemia

Authors: Valentina Gianfelici, Daniela Diverio, Massimo Breccia, Sonia Buffolino, Valentina Derme, Attilio Di Lascio, Marilisa Marinelli, Simona Santangelo, Giovanna Meloni, Robin Foà

Published in: Annals of Hematology | Issue 7/2011

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Excerpt

Dear Editor, …
Literature
1.
Reindl C, Bagrintseva K, Vempati S, Schnittger S, Ellwart JW, Wenig K, Hopfner KP, Hiddemann W, Spiekermann K (2006) Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML. Blood 107(9):3700–3707PubMedCrossRef
2.
Noguera NI, Breccia M, Divona M, Diverio D, Costa V, De Santis S, Avvisati G, Pinazzi MB, Petti MC, Mandelli F, Lo Coco F (2002) Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia 16:2185–2189PubMedCrossRef
3.
Stirewalt DL, Meshinchi S, Kussick SJ, Sheets KM, Pogosova-Agadjanyan E, Willman CL, Radich JP (2004) Novel FLT3 point mutations within exon 14 found in patients with acute myeloid leukaemia. Br J Haematol 124(4):481–484PubMedCrossRef
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Syampurnawati M, Tatsumi E, Furuta K, Hayashi Y (2007) Four novel point mutations in exons 12, 13, and 14 of the FLT3 gene. Leuk Res 31(6):877PubMedCrossRef
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Stam RW, den Boer ML, Schneider P, Meier M, Beverloo HP, Pieters R (2007) D-HPLC analysis of the entire FLT3 gene in MLL rearranged and hyperdiploid acute lymphoblastic leukemia. Haematologica 92(11):1565–1568PubMedCrossRef
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Stubbs MC, Kim YM, Krivtsov AV, Wright RD, Feng Z, Agarwal J, Kung AL, Armstrong SA (2008) MLL-AF9 and FLT3 cooperation in acute myelogeneous leukemia: development of a model for rapid therapeutic assessment. Leukemia 22(1):66–77PubMedCrossRef
Metadata
Title
A novel point mutation within the juxtamembrane domain of the flt3 gene in acute myeloid leukemia
Authors
Valentina Gianfelici
Daniela Diverio
Massimo Breccia
Sonia Buffolino
Valentina Derme
Attilio Di Lascio
Marilisa Marinelli
Simona Santangelo
Giovanna Meloni
Robin Foà
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Annals of Hematology / Issue 7/2011
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-010-1092-0

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