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Annals of Hematology
Published in: Annals of Hematology 7/2011

01-07-2011 | Letter to the Editor

MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi)

Authors: Kate L. Burbury, Mark J. Bishton, Ricky W. Johnstone, Michael J. Dickinson, Jeffrey Szer, H. Miles Prince

Published in: Annals of Hematology | Issue 7/2011

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Excerpt

Dear Editor, …
Literature
1.
2.
Sobulo OM, Borrow J, Tomek R et al (1997) MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci USA 94:8732–8737PubMedCrossRef
3.
Prince HM, Bishton MJ, Harrison SJ (2009) Clinical studies of histone deacetylase inhibitors. Clin Cancer Res 15:3958–3969PubMedCrossRef
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Prince HM, Bishton MJ, Johnstone RW (2009) Panobinostat (LBH589): a potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors. Future Oncol 5:601–612PubMedCrossRef
5.
Neff T, Armstrong SA (2009) Chromatin maps, histone modifications and leukemia. Leukemia 23:1243–1251PubMedCrossRef
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Dou Y, Hess JL (2008) Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia. Int J Hematol 87:10–18PubMedCrossRef
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Khobta A, Carlo-Stella C, Capranico G (2004) Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene. Cancer Res 64:2656–2662PubMedCrossRef
Metadata
Title
MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi)
Authors
Kate L. Burbury
Mark J. Bishton
Ricky W. Johnstone
Michael J. Dickinson
Jeffrey Szer
H. Miles Prince
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Annals of Hematology / Issue 7/2011
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-010-1099-6

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