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Open Access 01-02-2008 | Year in Review 2007

Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology

Authors: Massimo Antonelli, Elie Azoulay, Marc Bonten, Jean Chastre, Giuseppe Citerio, Giorgio Conti, Daniel De Backer, François Lemaire, Herwig Gerlach, Johan Groeneveld, Goran Hedenstierna, Duncan Macrae, Jordi Mancebo, Salvatore M. Maggiore, Alexandre Mebazaa, Philipp Metnitz, Jerôme Pugin, Jan Wernerman, Haibo Zhang

Published in: Intensive Care Medicine | Issue 2/2008

Excerpt

The “Experimental studies”, published either as original papers or as brief communications, focused on four main subjects, i. e. the mechanisms of lung injury and therapies, the treatment of burns and trauma, multiple organ failures and the pathophysiology and treatment of sepsis, severe sepsis and septic shock. …

Fraisse A, Bregeon F, Delpierre S, Gaudart J, Payan MJ, Pugin J, Papazian L (2007) Hemodynamics in experimental gastric juice induced aspiration pneumonitis. Intensive Care Med 33:300–307PubMedCrossRef

Eyal FG, Hamm CR, Parker JC (2007) Reduction in alveolar macrophages attenuates acute ventilator induced lung injury in rats. Intensive Care Med 33:1212–1218PubMedCrossRef

Lachmann RA, van Kaam AH, Haitsma JJ, Lachmann B (2007) High positive end-expiratory pressure levels promote bacterial translocation in experimental pneumonia. Intensive Care Med 33:1800–1804PubMedCrossRef

Testelmans D, Maes K, Wouters P, Powers SK, Decramer M, Gayan-Ramirez G (2007) Infusions of rocuronium and cisatracurium exert different effects on rat diaphragm function. Intensive Care Med 33:872–879PubMedCrossRef

Lindgren S, Odenstedt H, Olegard C, Sondergaard S, Lundin S, Stenqvist O (2007) Regional lung derecruitment after endotracheal suction during volume- or pressure-controlled ventilation: a study using electric impedance tomography. Intensive Care Med 33:172–180PubMedCrossRef

Duperret S, Lhuillier F, Piriou V, Vivier E, Metton O, Branche P, Annat G, Bendjelid K, Viale JP (2007) Increased intra-abdominal pressure affects respiratory variations in arterial pressure in normovolaemic and hypovolaemic mechanically ventilated healthy pigs. Intensive Care Med 33:163–171PubMedCrossRef

Richard JC, Bregeon F, Leray V, Le Bars D, Costes N, Tourvieille C, Lavenne F, Devouassoux-Shisheboran M, Gimenez G, Guerin C (2007) Effect of activated protein C on pulmonary blood flow and cytokine production in experimental acute lung injury. Intensive Care Med 33:2199–2206PubMedCrossRef

Muellenbach RM, Kredel M, Said HM, Klosterhalfen B, Zollhoefer B, Wunder C, Redel A, Schmidt M, Roewer N, Brederlau J (2007) High-frequency oscillatory ventilation reduces lung inflammation: a large-animal 24-h model of respiratory distress. Intensive Care Med 33:1423–1433PubMedCrossRef

Langenberg C, Wan L, Egi M, May CN, Bellomo R (2007) Renal blood flow and function during recovery from experimental septic acute kidney injury. Intensive Care Med 33:1614–1618PubMedCrossRef

10.

Cuzzocrea S, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Crisafulli C, Bramanti P, Thiemermann C (2007) Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut. Intensive Care Med 33:880–893PubMedCrossRef

11.

Meier C, Contaldo C, Schramm R, Holstein JH, Hamacher J, Amon M, Wanner GA, Trentz O, Menger MD (2007) Microdialysis of the rectus abdominis muscle for early detection of impending abdominal compartment syndrome. Intensive Care Med 33:1434–1443PubMedCrossRef

12.

Dubniks M, Persson J, Grande PO (2007) Effect of blood pressure on plasma volume loss in the rat under increased permeability. Intensive Care Med 33:2192–2198PubMedCrossRef

13.

Hamani D, Charrueau C, Butel MJ, Besson V, Belabed L, Nicolis I, Le Plenier S, Marchand-Leroux C, Chaumeil JC, Cynober L, Moinard C (2007) Effect of an immune-enhancing diet on lymphocyte in head-injured rats: what is the role of arginine? Intensive Care Med 33:1076–1084PubMedCrossRef

14.

Cynober L, Lasnier E, Le Boucher J, Jardel A, Coudray-Lucas C (2007) Effect of ornithine alpha-ketoglutarate on glutamine pools in burn injury: evidence of component interaction. Intensive Care Med 33:538–541PubMedCrossRef

15.

Dubin A, Murias G, Sottile JP, Pozo MO, Baran M, Edul VS, Canales HS, Etcheverry G, Maskin B, Estenssoro E (2007) Effects of levosimendan and dobutamine in experimental acute endotoxemia: a preliminary controlled study. Intensive Care Med 33:485–494PubMedCrossRef

16.

Levy B, Mansart A, Montemont C, Gibot S, Mallie JP, Regnault V, Lecompte T, Lacolley P (2007) Myocardial lactate deprivation is associated with decreased cardiovascular performance, decreased myocardial energetics, and early death in endotoxic shock. Intensive Care Med 33:495–502PubMedCrossRef

17.

Nielsen JS, Larsson A, Rix T, Nyboe R, Gjedsted J, Krog J, Ledet T, Tonnesen E (2007) The effect of activated protein C on plasma cytokine levels in a porcine model of acute endotoxemia. Intensive Care Med 33:1085–1093PubMedCrossRef

18.

Boost KA, Hoegl S, Hofstetter C, Flondor M, Stegewerth K, Platacis I, Pfeilschifter J, Muhl H, Zwissler B (2007) Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1 beta, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia. Intensive Care Med 33:863–871PubMedCrossRef

19.

Taniguchi T, Kurita A, Mukawa C, Yamamoto K, Inaba H (2007) Dose-related effects of direct hemoperfusion using a cytokine adsorbent column for the treatment of experimental endotoxemia. Intensive Care Med 33:529–533PubMedCrossRef

20.

Ozdemir D, Uysal N, Tugyan K, Gonenc S, Acikgoz O, Aksu I, Ozkan H (2007) The effect of melatonin on endotoxemia-induced intestinal apoptosis and oxidative stress in infant rats. Intensive Care Med 33:511–516PubMedCrossRef

21.

Temmesfeld-Wollbruck B, Brell B, David I, Dorenberg M, Adolphs J, Schmeck B, Suttorp N, Hippenstiel S (2007) Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock. Intensive Care Med 33:703–710PubMedCrossRef

22.

Albuszies G, Vogt J, Wachter U, Thiemermann C, Leverve XM, Weber S, Georgieff M, Radermacher P, Barth E (2007) The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock. Intensive Care Med 33:1094–1101PubMedCrossRef

23.

Cui X, Besch V, Khaibullina A, Hergen A, Quezado M, Eichacker P, Quezado ZM (2007) Neuronal nitric oxide synthase deficiency decreases survival in bacterial peritonitis and sepsis. Intensive Care Med 33:1993–2003PubMedCrossRef

24.

Ader F, Le Berre R, Lancel S, Faure K, Viget NB, Nowak E, Neviere R, Guery BP (2007) Inhaled nitric oxide increases endothelial permeability in Pseudomonas aeruginosa pneumonia. Intensive Care Med 33:503–510PubMedCrossRef

25.

Tuon L, Comim CM, Antunes MM, Constantino LS, Machado RA, Izquierdo I, Quevedo J, Dal-Pizzol F (2007) Imipramine reverses the depressive symptoms in sepsis survivor rats. Intensive Care Med 33:2165–2167PubMedCrossRef

26.

Oberbeck R, Deckert H, Bangen J, Kobbe P, Schmitz D (2007) Dehydroepiandrosterone: a modulator of cellular immunity and heat shock protein 70 production during polymicrobial sepsis. Intensive Care Med 33:2207–2213PubMedCrossRef

27.

Eisenbach C, Schonfeld AH, Vogt N, Wente MN, Encke J, Stremmel W, Martin E, Pfenninger E, Weigand MA (2007) Pharmacodynamics and organ storage of hydroxyethyl starch in acute hemodilution in pigs: Influence of molecular weightand degree of substitution. Intensive Care Med 33:1637–1644PubMedCrossRef

28.

Roch A, Blayac D, Ramiara P, Chetaille B, Marin V, Michelet P, Lambert D, Papazian L, Auffray JP, Carpentier JP (2007) Comparison of lung injury after normal or small volume optimized resuscitation in a model of hemorrhagic shock. Intensive Care Med 33:1645–1654PubMedCrossRef

29.

Brandao da Silva N, Martins L, Martins F, Anflor J Jr., Tonietto T, Koefender C, Cardoso PG, Moreira J (2007) Direct examination and cultures of bronchoalveolar lavage in pneumonia diagnosis: a comparative experimental study. Intensive Care Med 33:1840–1847PubMedCrossRef

30.

Timsit JF (2007) Bronchoalveolar lavage for VAP diagnosis: patients must be sampled before any change of antimicrobial therapy. Intensive Care Med 33:1690–1693PubMedCrossRef

31.

Maybauer MO, Maybauer DM, Fraser JF, Traber LD, Westphal M, Cox RA, Huda R, Nakano YY, Enkhbaatar P, Hawkins HK, Herndon DN, Traber DL (2007) Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock. Intensive Care Med 33:1219–1227PubMedCrossRef

32.

Chieregato A, Tanfani A, Compagnone C, Turrini C, Sarpieri F, Ravaldini M, Targa L, Fainardi E (2007) Global cerebral blood flow and CPP after severe head injury: a xenon-CT study. Intensive Care Med 33:856–862PubMedCrossRef

33.

Christ M, Noack F, Schroeder T, Hagmueller A, Koch R, May SA, Morgenstern U, Ragaller M, Steinmeier R (2007) Continuous cerebral autoregulation monitoring by improved cross-correlation analysis: comparison with the cuff deflation test. Intensive Care Med 33:246–254PubMedCrossRef

34.

Geeraerts T, Launey Y, Martin L, Pottecher J, Vigue B, Duranteau J, Benhamou D (2007) Ultrasonography of the optic nerve sheath may be useful for detecting raised intracranial pressure after severe brain injury. Intensive Care Med 33:1704–1711PubMedCrossRef

35.

Ract C, Le Moigno S, Bruder N, Vigue B (2007) Transcranial Doppler ultrasound goal-directed therapy for the early management of severe traumatic brain injury. Intensive Care Med 33:645–651PubMedCrossRef

36.

Longhi L, Pagan F, Valeriani V, Magnoni S, Zanier ER, Conte V, Branca V, Stocchetti N (2007) Monitoring brain tissue oxygen tension in brain-injured patients reveals hypoxic episodes in normal-appearing and in peri-focal tissue. Intensive Care Med 33:2136–2142PubMedCrossRef

37.

Ballesteros MA, Lopez-Hoyos M, Munoz P, Marin MJ, Minambres E (2007) Apoptosis of neuronal cells induced by serum of patients with acute brain injury: a new in vitro prognostic model. Intensive Care Med 33:58–65PubMedCrossRef

38.

Korfias S, Stranjalis G, Boviatsis E, Psachoulia C, Jullien G, Gregson B, Mendelow AD, Sakas DE (2007) Serum S-100B protein monitoring in patients with severe traumatic brain injury. Intensive Care Med 33:255–260PubMedCrossRef

39.

Citerio G, Gaini SM, Tomei G, Stocchetti N (2007) Management of 350 aneurysmal subarachnoid hemorrhages in 22 Italian neurosurgical centers. Intensive Care Med 33:1580–1586PubMedCrossRef

40.

Terao Y, Takada M, Tanabe T, Ando Y, Fukusaki M, Sumikawa K (2007) Microalbuminuria is a prognostic predictor in aneurysmal subarachnoid hemorrhage. Intensive Care Med 33:1000–1006PubMedCrossRef

41.

Appelboam R, Thomas EO (2007) The headache over warfarin in British neurosurgical intensive care units: a national survey of current practice. Intensive Care Med 33:1946–1953PubMedCrossRef

42.

Maier C, Scheuerle A, Hauser B, Schelzig H, Szabo C, Radermacher P, Kick J (2007) The selective poly(ADP)ribose-polymerase 1 inhibitor INO1001 reduces spinal cord injury during porcine aortic cross-clamping-induced ischemia/reperfusion injury. Intensive Care Med 33:845–850PubMedCrossRef

43.

Quesnel C, Fulgencio JP, Adrie C, Marro B, Payen L, Lembert N, El Metaoua S, Bonnet F (2007) Limitations of computed tomographic angiography in the diagnosis of brain death. Intensive Care Med 33:2129–2135PubMedCrossRef

44.

Wennervirta J, Salmi T, Hynynen M, Yli-Hankala A, Koivusalo AM, Van Gils M, Poyhia R, Vakkuri A (2007) Entropy is more resistant to artifacts than bispectral index in brain-dead organ donors. Intensive Care Med 33:133–136PubMedCrossRef

45.

Sharshar T, Carlier R, Bernard F, Guidoux C, Brouland JP, Nardi O, de la Grandmaison GL, Aboab J, Gray F, Menon D, Annane D (2007) Brain lesions in septic shock: a magnetic resonance imaging study. Intensive Care Med 33:798–806PubMedCrossRef

46.

Ouimet S, Riker R, Bergeon N, Cossette M, Kavanagh B, Skrobik Y (2007) Subsyndromal delirium in the ICU: evidence for a disease spectrum. Intensive Care Med 33:1007–1013PubMedCrossRef

47.

Pandharipande P, Cotton BA, Shintani A, Thompson J, Costabile S, Truman Pun B, Dittus R, Ely EW (2007) Motoric subtypes of delirium in mechanically ventilated surgical and trauma intensive care unit patients. Intensive Care Med 33:1726–1731PubMedCrossRef

48.

Deruddre S, Cheisson G, Mazoit JX, Vicaut E, Benhamou D, Duranteau J (2007) Renal arterial resistance in septic shock: effects of increasing mean arterial pressure with norepinephrine on the renal resistive index assessed with Doppler ultrasonography. Intensive Care Med 33:1557–1562PubMedCrossRef

49.

Herrera-Gutierrez ME, Seller-Perez G, Banderas-Bravo E, Munoz-Bono J, Lebron-Gallardo M, Fernandez-Ortega JF (2007) Replacement of 24-h creatinine clearance by 2-h creatinine clearance in intensive care unit patients: a single-center study. Intensive Care Med 33:1900–1906PubMedCrossRef

50.

Jenq CC, Tsai MH, Tian YC, Lin CY, Yang C, Liu NJ, Lien JM, Chen YC, Fang JT, Chen PC, Yang CW (2007) RIFLE classification can predict short-term prognosis in critically ill cirrhotic patients. Intensive Care Med 33:1921–1930PubMedCrossRef

51.

Maccariello E, Soares M, Valente C, Nogueira L, Valenca RV, Machado JE, Rocha E (2007) RIFLE classification in patients with acute kidney injury in need of renal replacement therapy. Intensive Care Med 33:597–605PubMedCrossRef

52.

Ridel C, Osman D, Mercadal L, Anguel N, Petitclerc T, Richard C, Vinsonneau C (2007) Ionic dialysance: a new valid parameter for quantification of dialysis efficiency in acute renal failure? Intensive Care Med 33:460–465PubMedCrossRef

53.

Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten H, Ronco C, Kellum JA (2007) Continuous renal replacement therapy: A worldwide practice survey : The Beginning and Ending Supportive Therapy for the Kidney (B.E.S.T. Kidney) Investigators. Intensive Care Med 33:1563–1570PubMedCrossRef

54.

Bell M, Granath F, Schon S, Ekbom A, Martling CR (2007) Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure. Intensive Care Med 33:773–780PubMedCrossRef

55.

Baldwin I, Naka T, Koch B, Fealy N, Bellomo R (2007) A pilot randomised controlled comparison of continuous veno-venous haemofiltration and extended daily dialysis with filtration: effect on small solutes and acid-base balance. Intensive Care Med 33:830–835PubMedCrossRef

56.

Joannidis M, Kountchev J, Rauchenzauner M, Schusterschitz N, Ulmer H, Mayr A, Bellmann R (2007) Enoxaparin vs. unfractionated heparin for anticoagulation during continuous veno-venous hemofiltration: a randomized controlled crossover study. Intensive Care Med 33:1571–1579PubMedCrossRef

57.

Berg A, Norberg A, Martling CR, Gamrin L, Rooyackers O, Wernerman J (2007) Glutamine kinetics during intravenous glutamine supplementation in ICU patients on continuous renal replacement therapy. Intensive Care Med 33:660–666PubMedCrossRef

58.

Weber-Carstens S, Deja M, Bercker S, Dimroth A, Ahlers O, Kaisers U, Keh D (2007) Impact of bolus application of low-dose hydrocortisone on glycemic control in septic shock patients. Intensive Care Med 33:730–733PubMedCrossRef

59.

Nguyen N, Ching K, Fraser R, Chapman M, Holloway R (2007) The relationship between blood glucose control and intolerance to enteral feeding during critical illness. Intensive Care Med 33:2085–2092PubMedCrossRef

60.

Meynaar IA, Dawson L, Tangkau PL, Salm EF, Rijks L (2007) Introduction and evaluation of a computerised insulin protocol. Intensive Care Med 33:591–596PubMedCrossRef

61.

Lacherade JC, Jabre P, Bastuji-Garin S, Grimaldi D, Fangio P, Theron V, Outin H, De Jonghe B (2007) Failure to achieve glycemic control despite intensive insulin therapy in a medical ICU: incidence and influence on ICU mortality. Intensive Care Med 33:814–821PubMedCrossRef

62.

Critchell CD, Savarese V, Callahan A, Aboud C, Jabbour S, Marik P (2007) Accuracy of bedside capillary blood glucose measurements in critically ill patients. Intensive Care Med 33:2079–2084PubMedCrossRef

63.

Dimopoulou I, Alevizopoulou P, Dafni U, Orfanos S, Livaditi O, Tzanela M, Kotanidou A, Souvatzoglou E, Kopterides P, Mavrou I, Thalassinos N, Roussos C, Armaganidis A, Tsagarakis S (2007) Pituitary-adrenal responses to human corticotropin-releasing hormone in critically ill patients. Intensive Care Med 33:454–459PubMedCrossRef

64.

De Waele JJ, Hoste EA, Baert D, Hendrickx K, Rijckaert D, Thibo P, Van Biervliet P, Blot SI, Colardyn F (2007) Relative adrenal insufficiency in patients with severe acute pancreatitis. Intensive Care Med 33:1754–1760PubMedCrossRef

65.

Riche FC, Boutron CM, Valleur P, Berton C, Laisne MJ, Launay JM, Chappuis P, Peynet J, Vicaut E, Payen D, Cholley BP (2007) Adrenal response in patients with septic shock of abdominal origin: relationship to survival. Intensive Care Med 33:1761–1766PubMedCrossRef

66.

Dimopoulou I, Stamoulis K, Ilias I, Tzanela M, Lyberopoulos P, Orfanos S, Armaganidis A, Theodorakopoulou M, Tsagarakis S (2007) A prospective study on adrenal cortex responses and outcome prediction in acute critical illness: results from a large cohort of 203 mixed ICU patients. Intensive Care Med 33:2116–2121PubMedCrossRef

67.

Venkatesh B, Cohen J, Hickman I, Nisbet J, Thomas P, Ward G, Hall J, Prins J (2007) Evidence of altered cortisol metabolism in critically ill patients: a prospective study. Intensive Care Med 33:1746–1753PubMedCrossRef

Title: Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology
Authors: Massimo Antonelli
Elie Azoulay
Marc Bonten
Jean Chastre
Giuseppe Citerio
Giorgio Conti
Daniel De Backer
François Lemaire
Herwig Gerlach
Johan Groeneveld
Goran Hedenstierna
Duncan Macrae
Jordi Mancebo
Salvatore M. Maggiore
Alexandre Mebazaa
Philipp Metnitz
Jerôme Pugin
Jan Wernerman
Haibo Zhang
Publication date: 01-02-2008
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 2/2008
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-007-0981-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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Short-term beneficial effects of methylene blue on kidney damage in septic shock patients