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01-05-2007 | Short Communication

Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis

Authors: Valerio Onofri, Federica Alessandrini, Chiara Turchi, Barbara Fraternale, Loredana Buscemi, Mauro Pesaresi, Adriano Tagliabracci

Published in: International Journal of Legal Medicine | Issue 3/2007

Abstract

To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.

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Berger B, Lindinger A, Niederstatter H, Grubwieser P, Parson W (2005) Y-STR typing of an Austrian population sample using a 17-loci multiplex PCR assay. Int J Legal Med 119:241–246PubMedCrossRef

Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York

DNA IQ™ System—Small sample casework protocol, Promega Company, http://www.promega.com/profiles/

Onofri V, Alessandrini F, Turchi C, Pesaresi M, Buscemi L, Tagliabracci A (2006) Development of multiplex PCRs for evolutionary and forensic applications of 37 human Y chromosome SNPs. Forensic Sci Int 157:23–35PubMedCrossRef

Alessandrini F, Turchi C, Onofri V, Buscemi L, Pesaresi M, Tagliabracci A (2005) Multiplex PCR development of Y-chromosomal biallelic polymorphisms for forensic application. J Forensic Sci 50(3):519–525PubMedCrossRef

Gusmao L, Butler JM, Carracedo A et al (2006) DNA Commission of the International Society for Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Int J Legal Med 120:191–200PubMedCrossRef

Mulero JJ, Budowle B, Butler JM, Gusmao L (2006) Letter to the editor—nomenclature and allele repeat structure update for the Y-STR locus GATA H4. J Forensic Sci 51(3):694PubMedCrossRef

Schneider S, Roessli D, Excoffier L (2000) Arlequin ver. 2.000: a software for population genetics data analysis. Genetics and Biometry Laboratory, University of Geneva, Switzerland

Turrina S, Atzei R, De Leo D (2006) Y-chromosomal STR haplotypes in Northeast Italian population sample using 17plex loci PCR assay. Int J Legal Med 120:56–59PubMedCrossRef

10.

Kwak KD, Jin HJ, Shin DJ et al (2005) Y-chromosomal STR haplotypes and their applications to forensic and population studies in east Asia. Int J Legal Med 119:195–201PubMedCrossRef

11.

Roewer L, Croucher PJP, Willuweit S et al (2005) Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Int J Legal Med 116:279–291

12.

Semino O, Passarino G, Oefner PJ et al (2000) The genetic legacy of Paleolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective. Science 290:1155–1159PubMedCrossRef

13.

Di Giacomo F, Luca F, Anagnou N et al (2003) Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects. Mol Phylogenet Evol 28:387–395PubMedCrossRef

Title: Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis
Authors: Valerio Onofri
Federica Alessandrini
Chiara Turchi
Barbara Fraternale
Loredana Buscemi
Mauro Pesaresi
Adriano Tagliabracci
Publication date: 01-05-2007
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 3/2007
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-007-0153-y

2024 ASCO Annual Meeting

Springer Medicine

Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

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