Skip to main content
Top
Published in: Archives of Public Health 1/2020

Open Access 01-12-2020 | Whooping Cough | Research

Vaccine coverage within the first year of life and associated factors with incomplete immunization in a Brazilian birth cohort

Authors: Romina Buffarini, Fernando C. Barros, Mariângela F. Silveira

Published in: Archives of Public Health | Issue 1/2020

Login to get access

Abstract

Background

Immunization has been held as a major achievement for global health, however, still exist many children who are not completely vaccinated. Knowledge about factors contributing to the incomplete immunization is important to develop effective strategies and interventions to achieve universal coverage to control or eradicate vaccine-preventable diseases. This study aimed to describe immunization coverage within the first year of life and associated factors with incompleteness among participants of the 2015 Pelotas Birth Cohort, Brazil.

Methods

Cross-sectional analyses were performed using data from a population-based cohort. Information on vaccination status was collected from immunization cards and verbal mother’s reports from 4014 children aged 24 months. Coverage was described for each vaccine, for the basic and the complete national schedule. Incomplete vaccination was defined as failure to receive the recommended number of doses by the National Immunization Program in 2015. Bivariate and multivariate Poisson regressions with robust variance were conducted to identify factors associated with incompleteness.

Results

Vaccine coverage of individual vaccines varied from 81% (Hepatitis A) to 97% (BCG). Full immunization coverage were 77% (95% CI: 75.8; 78.4) and 66.1% (95% CI: 64.6; 67.5), for basic and expanded indicators, relatively. Multivariate analyses showed that factors associated with incompleteness (for both basic and expanded coverage) were high family income, high parity, low number of prenatal consultations, not have done the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy, not have breastfeed the child until at age 12 months and not have used public health care services for child’s vaccination.

Conclusion

Findings of our study show the need to develop and implement policies and programs to achieve complete immunization during the first year of life. Some strategies would include an increase in the primary health care services networks, improving their quality and access, the dissemination of scientific-based evidence about the benefits of vaccination, through communication campaigns and guidance provided by health professionals, especially those responsible for prenatal care.
Appendix
Available only for authorised users
Literature
1.
go back to reference Bustreo F, Okwo-Bele JM, Kamara L. World Health Organization perspectives on the contribution of the global Alliance for vaccines and immunization on reducing child mortality. Arch Dis Child. 2015;100(Suppl 1):S34–7.CrossRef Bustreo F, Okwo-Bele JM, Kamara L. World Health Organization perspectives on the contribution of the global Alliance for vaccines and immunization on reducing child mortality. Arch Dis Child. 2015;100(Suppl 1):S34–7.CrossRef
2.
go back to reference WHO. Meeting of the immunization strategic advisory Group of Experts, November 2008--conclusions and recommendations. Releve epidemiologique hebdomadaire. 2009;84(1–2):1–16. WHO. Meeting of the immunization strategic advisory Group of Experts, November 2008--conclusions and recommendations. Releve epidemiologique hebdomadaire. 2009;84(1–2):1–16.
3.
go back to reference Rainey JJ, Watkins M, Ryman TK, Sandhu P, Bo A, Banerjee K. Reasons related to non-vaccination and under-vaccination of children in low and middle income countries: findings from a systematic review of the published literature, 1999-2009. Vaccine. 2011;29(46):8215–21.CrossRef Rainey JJ, Watkins M, Ryman TK, Sandhu P, Bo A, Banerjee K. Reasons related to non-vaccination and under-vaccination of children in low and middle income countries: findings from a systematic review of the published literature, 1999-2009. Vaccine. 2011;29(46):8215–21.CrossRef
4.
go back to reference Paim J, Travassos C, Almeida C, Bahia L, Macinko J. The Brazilian health system: history, advances, and challenges. Lancet (London, England). 2011;377(9779):1778–97.CrossRef Paim J, Travassos C, Almeida C, Bahia L, Macinko J. The Brazilian health system: history, advances, and challenges. Lancet (London, England). 2011;377(9779):1778–97.CrossRef
5.
go back to reference Ministério da Saúde . Secretaria de Vigilância em Saúde. Programa Nacional de Imunizações: aspectos históricos dos calendários de vacinação e avanços dos indicadores de coberturas vacinais, no período de 1980 a 2013. Bol Epidemiol. 2015;46(30):1–13. Ministério da Saúde . Secretaria de Vigilância em Saúde. Programa Nacional de Imunizações: aspectos históricos dos calendários de vacinação e avanços dos indicadores de coberturas vacinais, no período de 1980 a 2013. Bol Epidemiol. 2015;46(30):1–13.
7.
go back to reference Sato APS. What is the importance of vaccine hesitancy in the drop of vaccination coverage in Brazil? Rev Saude Publica. 2018;52:96.CrossRef Sato APS. What is the importance of vaccine hesitancy in the drop of vaccination coverage in Brazil? Rev Saude Publica. 2018;52:96.CrossRef
9.
10.
go back to reference Yokokura AVCP, Silva AAMd, Bernardes ACF, Lamy Filho F, Alves MTSSdB, Cabra NAL, et al. Cobertura vacinal e fatores associados ao esquema vacinal básico incompleto aos 12 meses de idade, São Luís, Maranhão, Brasil, 2006. Cad Saude Publica 2013;29:522–534.CrossRef Yokokura AVCP, Silva AAMd, Bernardes ACF, Lamy Filho F, Alves MTSSdB, Cabra NAL, et al. Cobertura vacinal e fatores associados ao esquema vacinal básico incompleto aos 12 meses de idade, São Luís, Maranhão, Brasil, 2006. Cad Saude Publica 2013;29:522–534.CrossRef
11.
go back to reference Silva AAM, Gomes UA, Tonial SR, Silva RA. Cobertura vacinal e fatores de Risco associados à não-vacinação em localidade Urbana do Nordeste brasileiro, 1994. Rev Saude Publica. 1999;33:147–56.CrossRef Silva AAM, Gomes UA, Tonial SR, Silva RA. Cobertura vacinal e fatores de Risco associados à não-vacinação em localidade Urbana do Nordeste brasileiro, 1994. Rev Saude Publica. 1999;33:147–56.CrossRef
12.
go back to reference Silva FS, Barbosa YC, Batalha MA, Ribeiro MRC, Simões VMF, Branco MRFC, et al. Incomplete childhood immunization with new and old vaccines and associated factors: BRISA birth cohort, São Luís, Maranhão state, Northeast Brazil. Cad Saude Publica. 2018;34(3):e00041717.CrossRef Silva FS, Barbosa YC, Batalha MA, Ribeiro MRC, Simões VMF, Branco MRFC, et al. Incomplete childhood immunization with new and old vaccines and associated factors: BRISA birth cohort, São Luís, Maranhão state, Northeast Brazil. Cad Saude Publica. 2018;34(3):e00041717.CrossRef
13.
go back to reference Barata RB, Pereira SM. Desigualdades sociais e cobertura vacinal na cidade de Salvador, Bahia. Rev Bras Epidemiol. 2013;16:266–77.CrossRef Barata RB, Pereira SM. Desigualdades sociais e cobertura vacinal na cidade de Salvador, Bahia. Rev Bras Epidemiol. 2013;16:266–77.CrossRef
14.
go back to reference de Moraes JC, Barata R, Ribeiro MC, de Castro PC. Vaccination coverage in the first year of life in 4 cities of the state of Sao Paulo, Brazil. Revista panamericana de salud publica = Pan Am J Public Health. 2000;8(5):332–41.CrossRef de Moraes JC, Barata R, Ribeiro MC, de Castro PC. Vaccination coverage in the first year of life in 4 cities of the state of Sao Paulo, Brazil. Revista panamericana de salud publica = Pan Am J Public Health. 2000;8(5):332–41.CrossRef
15.
go back to reference Wiysonge CS, Uthman OA, Ndumbe PM, Hussey GD. Individual and contextual factors associated with low childhood immunisation coverage in sub-Saharan Africa: a multilevel analysis. PLoS One. 2012;7(5):e37905.CrossRef Wiysonge CS, Uthman OA, Ndumbe PM, Hussey GD. Individual and contextual factors associated with low childhood immunisation coverage in sub-Saharan Africa: a multilevel analysis. PLoS One. 2012;7(5):e37905.CrossRef
16.
go back to reference Mutua MK, Kimani-Murage E, Ngomi N, Ravn H, Mwaniki P, Echoka E. Fully immunized child: coverage, timing and sequencing of routine immunization in an urban poor settlement in Nairobi, Kenya. Trop Med Health. 2016;44(1):13.CrossRef Mutua MK, Kimani-Murage E, Ngomi N, Ravn H, Mwaniki P, Echoka E. Fully immunized child: coverage, timing and sequencing of routine immunization in an urban poor settlement in Nairobi, Kenya. Trop Med Health. 2016;44(1):13.CrossRef
17.
go back to reference Barata RB, Ribeiro MC, de Moraes JC, Flannery B. Socioeconomic inequalities and vaccination coverage: results of an immunisation coverage survey in 27 Brazilian capitals, 2007-2008. J Epidemiol Community Health. 2012;66(10):934–41.CrossRef Barata RB, Ribeiro MC, de Moraes JC, Flannery B. Socioeconomic inequalities and vaccination coverage: results of an immunisation coverage survey in 27 Brazilian capitals, 2007-2008. J Epidemiol Community Health. 2012;66(10):934–41.CrossRef
18.
go back to reference Queiroz LLC, Monteiro SG, Mochel EG, Veras MASM, Sousa FGM, Bezerra MLM, et al. Cobertura vacinal do esquema básico Para o primeiro ano de Vida nas capitais do Nordeste brasileiro. Cad Saude Publica. 2013;29:294–302.CrossRef Queiroz LLC, Monteiro SG, Mochel EG, Veras MASM, Sousa FGM, Bezerra MLM, et al. Cobertura vacinal do esquema básico Para o primeiro ano de Vida nas capitais do Nordeste brasileiro. Cad Saude Publica. 2013;29:294–302.CrossRef
20.
go back to reference Hallal PC, Bertoldi AD, Domingues MR, da Silveira MF, Demarco FF, da Silva ICM, et al. Cohort profile: the 2015 Pelotas (Brazil) birth cohort study. Int J Epidemiol. 2018;47(4):1048-h.CrossRef Hallal PC, Bertoldi AD, Domingues MR, da Silveira MF, Demarco FF, da Silva ICM, et al. Cohort profile: the 2015 Pelotas (Brazil) birth cohort study. Int J Epidemiol. 2018;47(4):1048-h.CrossRef
22.
go back to reference Ministério de Saúde. PORTARIA n° 570, de 1° de JUNHO de 2000; 2000. Ministério de Saúde. PORTARIA n° 570, de 1° de JUNHO de 2000; 2000.
24.
go back to reference Ozawa S, Stack ML. Public trust and vaccine acceptance--international perspectives. Hum Vaccin Immunother. 2013;9(8):1774–8.CrossRef Ozawa S, Stack ML. Public trust and vaccine acceptance--international perspectives. Hum Vaccin Immunother. 2013;9(8):1774–8.CrossRef
25.
go back to reference Smith PJ, Kennedy AM, Wooten K, Gust DA, Pickering LK. Association between health care providers' influence on parents who have concerns about vaccine safety and vaccination coverage. Pediatrics. 2006;118(5):e1287–e92.CrossRef Smith PJ, Kennedy AM, Wooten K, Gust DA, Pickering LK. Association between health care providers' influence on parents who have concerns about vaccine safety and vaccination coverage. Pediatrics. 2006;118(5):e1287–e92.CrossRef
26.
go back to reference McClure CC, Cataldi JR, O'Leary ST. Vaccine hesitancy: where we are and where we are going. Clin Ther. 2017;39(8):1550–62.CrossRef McClure CC, Cataldi JR, O'Leary ST. Vaccine hesitancy: where we are and where we are going. Clin Ther. 2017;39(8):1550–62.CrossRef
27.
go back to reference Branco FL, Pereira TM, Delfino BM, Brana AM, Oliart-Guzman H, Mantovani SA, et al. Socioeconomic inequalities are still a barrier to full child vaccine coverage in the Brazilian Amazon: a cross-sectional study in Assis Brasil, acre, Brazil. Int J Equity Health. 2014;13:118.CrossRef Branco FL, Pereira TM, Delfino BM, Brana AM, Oliart-Guzman H, Mantovani SA, et al. Socioeconomic inequalities are still a barrier to full child vaccine coverage in the Brazilian Amazon: a cross-sectional study in Assis Brasil, acre, Brazil. Int J Equity Health. 2014;13:118.CrossRef
28.
go back to reference Tauil MC, Sato APS, Costa ÂA, Inenami M, VLdR F, Waldman EA. Coberturas vacinais por doses recebidas e oportunas com base em um Registro informatizado de imunização, Araraquara-SP, Brasil, 2012-2014. Epidemiologia e Serviços de Saúde. 2017;26:835–46.CrossRef Tauil MC, Sato APS, Costa ÂA, Inenami M, VLdR F, Waldman EA. Coberturas vacinais por doses recebidas e oportunas com base em um Registro informatizado de imunização, Araraquara-SP, Brasil, 2012-2014. Epidemiologia e Serviços de Saúde. 2017;26:835–46.CrossRef
29.
go back to reference Oleribe O, Kumar V, Awosika-Olumo A, Taylor-Robinson SD. Individual and socioeconomic factors associated with childhood immunization coverage in Nigeria. Pan Afr Med J. 2017;26:220.CrossRef Oleribe O, Kumar V, Awosika-Olumo A, Taylor-Robinson SD. Individual and socioeconomic factors associated with childhood immunization coverage in Nigeria. Pan Afr Med J. 2017;26:220.CrossRef
30.
go back to reference Bondy JN, Thind A, Koval JJ, Speechley KN. Identifying the determinants of childhood immunization in the Philippines. Vaccine. 2009;27(1):169–75.CrossRef Bondy JN, Thind A, Koval JJ, Speechley KN. Identifying the determinants of childhood immunization in the Philippines. Vaccine. 2009;27(1):169–75.CrossRef
32.
go back to reference Barreto ML, Teixeira MG, Bastos FI, Ximenes RA, Barata RB, Rodrigues LC. Successes and failures in the control of infectious diseases in Brazil: social and environmental context, policies, interventions, and research needs. Lancet (London, England). 2011;377(9780):1877–89.CrossRef Barreto ML, Teixeira MG, Bastos FI, Ximenes RA, Barata RB, Rodrigues LC. Successes and failures in the control of infectious diseases in Brazil: social and environmental context, policies, interventions, and research needs. Lancet (London, England). 2011;377(9780):1877–89.CrossRef
33.
go back to reference Castro MC, Massuda A, Almeida G, Menezes-Filho NA, Andrade MV, de Souza Noronha KVM, et al. Brazil's unified health system: the first 30 years and prospects for the future. Lancet (London, England). 2019;394(10195):345–56.CrossRef Castro MC, Massuda A, Almeida G, Menezes-Filho NA, Andrade MV, de Souza Noronha KVM, et al. Brazil's unified health system: the first 30 years and prospects for the future. Lancet (London, England). 2019;394(10195):345–56.CrossRef
34.
go back to reference Valadez JJ, Weld LH. Maternal recall error of child vaccination status in a developing nation. Am J Public Health. 1992;82(1):120–2.CrossRef Valadez JJ, Weld LH. Maternal recall error of child vaccination status in a developing nation. Am J Public Health. 1992;82(1):120–2.CrossRef
35.
go back to reference Binyaruka P, Borghi J. Validity of parental recalls to estimate vaccination coverage: evidence from Tanzania. BMC Health Serv Res. 2018;18(1):440.CrossRef Binyaruka P, Borghi J. Validity of parental recalls to estimate vaccination coverage: evidence from Tanzania. BMC Health Serv Res. 2018;18(1):440.CrossRef
37.
go back to reference Ryman TK, Dietz V, Cairns KL. Too little but not too late: results of a literature review to improve routine immunization programs in developing countries. BMC Health Serv Res. 2008;8:134.CrossRef Ryman TK, Dietz V, Cairns KL. Too little but not too late: results of a literature review to improve routine immunization programs in developing countries. BMC Health Serv Res. 2008;8:134.CrossRef
Metadata
Title
Vaccine coverage within the first year of life and associated factors with incomplete immunization in a Brazilian birth cohort
Authors
Romina Buffarini
Fernando C. Barros
Mariângela F. Silveira
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Archives of Public Health / Issue 1/2020
Electronic ISSN: 2049-3258
DOI
https://doi.org/10.1186/s13690-020-00403-4

Other articles of this Issue 1/2020

Archives of Public Health 1/2020 Go to the issue