Published in:
01-12-2016 | What's New in Intensive Care
What’s new on balanced crystalloid solutions?
Authors:
Paul Young, Flavia R. Machado, Simon Finfer
Published in:
Intensive Care Medicine
|
Issue 12/2016
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Excerpt
Intravenous fluid therapy is fundamental to the management of acutely ill patients and includes fluid resuscitation to treat hypovolaemia, replacement of ongoing fluid loses, and the provision of maintenance fluids to meet basal requirements for patients unable to drink. A range of crystalloid fluids are available including 0.9 % saline (saline), glucose solutions, and various balanced crystalloids [
1]. Saline contains 154 mmol/L of chloride compared with ~100 mmol/L in normal human plasma. While balanced crystalloids have chloride concentrations more closely approximating plasma, they contain anions such as lactate and acetate in non-physiological concentrations. …