Skip to main content
Top
Published in: Intensive Care Medicine 12/2016

01-12-2016 | What's New in Intensive Care

What’s new on balanced crystalloid solutions?

Authors: Paul Young, Flavia R. Machado, Simon Finfer

Published in: Intensive Care Medicine | Issue 12/2016

Login to get access

Excerpt

Intravenous fluid therapy is fundamental to the management of acutely ill patients and includes fluid resuscitation to treat hypovolaemia, replacement of ongoing fluid loses, and the provision of maintenance fluids to meet basal requirements for patients unable to drink. A range of crystalloid fluids are available including 0.9 % saline (saline), glucose solutions, and various balanced crystalloids [1]. Saline contains 154 mmol/L of chloride compared with ~100 mmol/L in normal human plasma. While balanced crystalloids have chloride concentrations more closely approximating plasma, they contain anions such as lactate and acetate in non-physiological concentrations. …
Literature
1.
go back to reference Reddy S, Weinberg L, Young P (2016) Crystalloid fluid therapy. Crit Care 20:1–9CrossRef Reddy S, Weinberg L, Young P (2016) Crystalloid fluid therapy. Crit Care 20:1–9CrossRef
2.
3.
go back to reference Bellomo R, Morimatsu H, French C, Cole L, Story D, Uchino S, Naka T, Investigators SS (2006) The effects of saline or albumin resuscitation on acid-base status and serum electrolytes. Crit Care Med 34:2891–2897CrossRefPubMed Bellomo R, Morimatsu H, French C, Cole L, Story D, Uchino S, Naka T, Investigators SS (2006) The effects of saline or albumin resuscitation on acid-base status and serum electrolytes. Crit Care Med 34:2891–2897CrossRefPubMed
4.
go back to reference Weinberg L, Pearce B, Sullivan R, Siu L, Scurrah N, Tan C, Backstrom M, Nikfarjam M, McNicol L, Story D, Christophi C, Bellomo R (2014) The effects of plasmalyte-148 versus hartmann’s solution during major liver resection: a multicentre, double-blind, randomized controlled trial. Minerva Anestesiol 81(12):1288–1297PubMed Weinberg L, Pearce B, Sullivan R, Siu L, Scurrah N, Tan C, Backstrom M, Nikfarjam M, McNicol L, Story D, Christophi C, Bellomo R (2014) The effects of plasmalyte-148 versus hartmann’s solution during major liver resection: a multicentre, double-blind, randomized controlled trial. Minerva Anestesiol 81(12):1288–1297PubMed
5.
go back to reference Hammond NE, Taylor C, Saxena M, Liu B, Finfer S, Glass P, Seppelt I, Willenberg L, Myburgh J (2015) Resuscitation fluid use in Australian and New Zealand Intensive Care Units between 2007 and 2013. Intensive Care Med 41:1611–1619CrossRefPubMed Hammond NE, Taylor C, Saxena M, Liu B, Finfer S, Glass P, Seppelt I, Willenberg L, Myburgh J (2015) Resuscitation fluid use in Australian and New Zealand Intensive Care Units between 2007 and 2013. Intensive Care Med 41:1611–1619CrossRefPubMed
6.
go back to reference Shaw AD, Bagshaw SM, Goldstein SL, Scherer LA, Duan M, Schermer CR, Kellum JA (2012) Major complications, mortality, and resource utilization after open abdominal surgery: 0.9 % saline compared to Plasma-Lyte. Ann Surg 255:821–829CrossRefPubMed Shaw AD, Bagshaw SM, Goldstein SL, Scherer LA, Duan M, Schermer CR, Kellum JA (2012) Major complications, mortality, and resource utilization after open abdominal surgery: 0.9 % saline compared to Plasma-Lyte. Ann Surg 255:821–829CrossRefPubMed
7.
go back to reference Raghunathan K, Shaw A, Nathanson B, Sturmer T, Brookhart A, Stefan MS, Setoguchi S, Beadles C, Lindenauer PK (2014) Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*. Crit Care Med 42:1585–1591CrossRefPubMed Raghunathan K, Shaw A, Nathanson B, Sturmer T, Brookhart A, Stefan MS, Setoguchi S, Beadles C, Lindenauer PK (2014) Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*. Crit Care Med 42:1585–1591CrossRefPubMed
8.
go back to reference Shaw AD, Raghunathan K, Peyerl FW, Munson SH, Paluszkiewicz SM, Schermer CR (2014) Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS. Intensive Care Med 40:1897–1905CrossRefPubMedPubMedCentral Shaw AD, Raghunathan K, Peyerl FW, Munson SH, Paluszkiewicz SM, Schermer CR (2014) Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS. Intensive Care Med 40:1897–1905CrossRefPubMedPubMedCentral
9.
go back to reference Krajewski ML, Raghunathan K, Paluszkiewicz SM, Schermer CR, Shaw AD (2015) Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation. Br J Surg 102:24–36CrossRefPubMed Krajewski ML, Raghunathan K, Paluszkiewicz SM, Schermer CR, Shaw AD (2015) Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation. Br J Surg 102:24–36CrossRefPubMed
10.
go back to reference Yunos NM, Bellomo R, Hegarty C, Story D, Ho L, Bailey M (2012) Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. JAMA J Am Med Assoc 308:1566–1572CrossRef Yunos NM, Bellomo R, Hegarty C, Story D, Ho L, Bailey M (2012) Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. JAMA J Am Med Assoc 308:1566–1572CrossRef
11.
go back to reference Bayer O, Reinhart K, Sakr Y, Kabisch B, Kohl M, Riedemann NC, Bauer M, Settmacher U, Hekmat K, Hartog CS (2011) Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: a prospective sequential comparison. Crit Care Med 39:1335–1342CrossRefPubMed Bayer O, Reinhart K, Sakr Y, Kabisch B, Kohl M, Riedemann NC, Bauer M, Settmacher U, Hekmat K, Hartog CS (2011) Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: a prospective sequential comparison. Crit Care Med 39:1335–1342CrossRefPubMed
12.
go back to reference Shaw AD, Schermer CR, Lobo DN, Munson SH, Khangulov V, Hayashida DK, Kellum JA (2015) Impact of intravenous fluid composition on outcomes in patients with systemic inflammatory response syndrome. Crit Care 19:334CrossRefPubMedPubMedCentral Shaw AD, Schermer CR, Lobo DN, Munson SH, Khangulov V, Hayashida DK, Kellum JA (2015) Impact of intravenous fluid composition on outcomes in patients with systemic inflammatory response syndrome. Crit Care 19:334CrossRefPubMedPubMedCentral
13.
go back to reference Rochwerg B, Alhazzani W, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, Mbuagbaw L, Szczeklik W, Alshamsi F, Altayyar S, Ip WC, Li G, Wang M, Wludarczyk A, Zhou Q, Guyatt GH, Cook DJ, Jaeschke R, Annane D (2014) Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med 161:347–355. doi:10.7326/M14-0178 CrossRefPubMed Rochwerg B, Alhazzani W, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, Mbuagbaw L, Szczeklik W, Alshamsi F, Altayyar S, Ip WC, Li G, Wang M, Wludarczyk A, Zhou Q, Guyatt GH, Cook DJ, Jaeschke R, Annane D (2014) Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med 161:347–355. doi:10.​7326/​M14-0178 CrossRefPubMed
14.
go back to reference Rochwerg B, Alhazzani W, Gibson A, Ribic CM, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, Mbuagbaw L, Szczeklik W, Alshamsi F, Altayyar S, Ip W, Li G, Wang M, Wludarczyk A, Zhou Q, Annane D, Cook DJ, Jaeschke R, Guyatt GH, Group F (2015) Fluid type and the use of renal replacement therapy in sepsis: a systematic review and network meta-analysis. Intensive Care Med 41:1561–1571CrossRefPubMed Rochwerg B, Alhazzani W, Gibson A, Ribic CM, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, Mbuagbaw L, Szczeklik W, Alshamsi F, Altayyar S, Ip W, Li G, Wang M, Wludarczyk A, Zhou Q, Annane D, Cook DJ, Jaeschke R, Guyatt GH, Group F (2015) Fluid type and the use of renal replacement therapy in sepsis: a systematic review and network meta-analysis. Intensive Care Med 41:1561–1571CrossRefPubMed
15.
go back to reference Young P, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, McGuinness S, Mehrtens J, Myburgh J, Psirides A, Reddy S, Bellomo R, Investigators S, Anzics CTG (2015) Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial. JAMA J Am Med Assoc 314:1701–1710CrossRef Young P, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, McGuinness S, Mehrtens J, Myburgh J, Psirides A, Reddy S, Bellomo R, Investigators S, Anzics CTG (2015) Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial. JAMA J Am Med Assoc 314:1701–1710CrossRef
Metadata
Title
What’s new on balanced crystalloid solutions?
Authors
Paul Young
Flavia R. Machado
Simon Finfer
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 12/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-016-4498-x

Other articles of this Issue 12/2016

Intensive Care Medicine 12/2016 Go to the issue

Correspondence

Tardive tachypnea

Imaging in Intensive Care Medicine

Common femoral artery pseudoaneurysm