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Current Cardiology Reports
Published in: Current Cardiology Reports 3/2012

01-06-2012 | Clinical Trial Report

What Have We Learned About Loop Diuretics in Acute Decompensated Heart Failure? The DOSE Trial

Authors: Dmitry Shchekochikhin, JoAnn Lindenfeld

Published in: Current Cardiology Reports | Issue 3/2012

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Excerpt

Trial: Felker GM, Lee KL, Bull DA, Redfield MM, Stevenson LW, Goldsmith SR, LeWinter MM, Deswal A, Rouleau JL, Ofili EO, Anstrom KJ, Hernandez AF, McNulty SE, Velazquez EJ, Kfoury AG, Chen HH, Givertz MM, Semigran MJ, Bart BA, Mascette AM, Braunwald E, O'Connor CM; NHLBI Heart Failure Clinical Research Network. Diuretic strategies in patients with acute decompensated heart failure. N Engl J Med 2011; 364:797–805. …
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Schrier RW, Ecder T. Unifying hypothesis of body fluid volume regulation: implications for cardiac failure and cirrhosis. Mt Sinai J Med. 2001;68:350–61.PubMed
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Adams Jr KF, Fonarow GC, Emerman CL, For the ADHERE Scientific Advisory Committee and Investigators, et al. Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the acute Decompensated Failure National Registry (ADHERE). Am Heart J. 2005;149:209–16.PubMedCrossRef
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Schrier RW. Role of diminished renal function in cardiovascular mortality: marker or pathogenetic factor? J Am Coll Cardiol. 2006;47:1–8.PubMedCrossRef
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Eshaghian S, Horwich TB, Fonarow GC. Relation of loop diuretic dose to mortality in advance heart failure. Am J Cardiol. 2006;97:1759–64.PubMedCrossRef
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Salvador DR, Rey NR, Ramos GC, Punzalan FE. Continuous infusion versus bolus injection of loop diuretics in congestive heart failure. Cochrane Database Syst Rev. 2005;20(3):CD003178.
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Butler J, Forman DE, Abraham WT, et al. Relationship between heart failure treatment and development of worsening renal function among hospitalized patients. Am Heart J. 2004;147-331-8.
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Forman DE, Butler J, Wang Y, Abraham WT, O'Connor CM, Gottlieb SS, Loh E, Massie BM, Rich MW, Stevenson LW, Young JB, Krumholz HM. Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure. J Am Coll Cardiol. 2004;43:61–7.PubMedCrossRef
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Aronson D, Burger AJ. The relationship between transient and persistent worsening renal function and mortality in patients with acute decompensated heart failure. J Card Fail. 2010;16:541–7.PubMedCrossRef
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Testani JM, Chen J, McCauley BD, Kimmel SE, Shannon RP. Potential effects of aggressive decongestion during the treatment of decompensated heart failure on renal function and survival. Circulation. 2010;122:265–72.PubMedCrossRef
Metadata
Title
What Have We Learned About Loop Diuretics in Acute Decompensated Heart Failure? The DOSE Trial
Authors
Dmitry Shchekochikhin
JoAnn Lindenfeld
Publication date
01-06-2012
Publisher
Current Science Inc.
Published in
Current Cardiology Reports / Issue 3/2012
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-012-0254-1

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