Published in:
01-09-2018 | Case Report
What Do We Need to Know About Colonic Polypoid Ganglioneuroma? A Case Report and A Comprehensive Review
Authors:
Mohamed Abdelfatah, George Sangah, Glenn Harvin
Published in:
Journal of Gastrointestinal Cancer
|
Issue 3/2018
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Excerpt
Intestinal ganglioneuromas (GNs) are rare well-differentiated, slowly growing neuroectodermal neoplasms mainly formed of nerve fibers, ganglion cells, and supporting cells [
1]. There are three types of GNs: polypoid GNs, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. Polypoid GNs are the most common type and are typically found incidentally on colonoscopies as a solitary polyp involving the mucosa and submucosa that could resemble an adenoma, a hyperplastic, or a juvenile polyp. Ganglioneuromatous polyposis is characterized by more than 20 sessile or pedunculated mucosal or submucosal lesions that endoscopically resemble familial adenomatous polyposis. Diffuse ganglioneuromatosis is a large poorly-demarcated nodular and disseminated proliferation of ganglioneuromatous tissue [
1]. Typically, ganglioneuromatosis are large (up to 17 cm), poorly demarcated, and often infiltrate the adjacent bowel wall and distort the surrounding tissue architecture. …