Published in:
01-03-2012 | Head and Neck Cancer (T Day, Section Editor)
Well Differentiated Thyroid Carcinoma: Current Treatment
Authors:
J. Kenneth Byrd, MD, Robert J. Yawn, BS, Christina S. T. Wilhoit, BA, CCRP, Nicoleta D. Sora, MD, Linda Meyers, MD, Jyotika Fernandes, MD, Terry Day, MD
Published in:
Current Treatment Options in Oncology
|
Issue 1/2012
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Opinion statement
Well differentiated thyroid carcinoma (WDTC) is a relatively common malignancy accounting for an estimated 37,000 thousand cases in the United States in 2009 [
1]. WDTC also has a generally high 5 year survival rate that correlates with age. Papillary thyroid carcinoma (PTC) greater than 1 cm is best managed by total thyroidectomy. Thyroid lobectomy and isthmusectomy may be adequate for unifocal PTC less than 1 cm in patients without negative prognostic factors. Central compartment and possible lateral neck dissections should be performed when nodal metastases are present in the respective nodal basins. Post-operatively, radioactive iodine ablation with
131I followed by thyroid stimulating hormone (TSH) suppression is indicated in certain patients to improve locoregional control and reduce recurrence.