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Published in: Journal of General Internal Medicine 11/2016

01-11-2016 | Letter to the Editor

Vitamin D: Ten Beliefs

Authors: G. Michael Allan, MD, James McCormack, PharmD, Christina Korownyk, MD

Published in: Journal of General Internal Medicine | Issue 11/2016

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Excerpt

Dr. Grant raises some interesting points regarding our publication, “Vitamin D: A Narrative Review Examining the Evidence for Ten Beliefs.”1 First, he recommends that nutrients should be viewed through a different research lens than pharmaceutical drugs. Serum levels should be done, only those with low levels should be randomized, vitamin D should be given sufficiently to raise levels to certain targets and then differences in outcomes assessed. This is certainly an attractive hypothesis and worthy of testing. However, in the absence of high quality randomized trials, this suggestion remains a hypothesis. Until proven, we have to rely on the best available evidence, such as that presented in our review. …
Literature
1.
go back to reference Allan GM, Cranston L, Lindblad A, McCormack J, Kolber MR, Garrison S, Korownyk C. Vitamin D: A Narrative Review Examining the Evidence for Ten Beliefs. J Gen Intern Med. doi: 10.1007/s11606-016-3645-y. Allan GM, Cranston L, Lindblad A, McCormack J, Kolber MR, Garrison S, Korownyk C. Vitamin D: A Narrative Review Examining the Evidence for Ten Beliefs. J Gen Intern Med. doi: 10.​1007/​s11606-016-3645-y.
2.
go back to reference Bolland MJ, Grey A, Gamble GD, Reid IR. The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2014;2(4):307–320.CrossRefPubMed Bolland MJ, Grey A, Gamble GD, Reid IR. The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2014;2(4):307–320.CrossRefPubMed
3.
go back to reference Manaseki-Holland S, Maroof Z, Bruce J, et al. Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet. 2012;379(9824):1419–27.CrossRefPubMedPubMedCentral Manaseki-Holland S, Maroof Z, Bruce J, et al. Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet. 2012;379(9824):1419–27.CrossRefPubMedPubMedCentral
Metadata
Title
Vitamin D: Ten Beliefs
Authors
G. Michael Allan, MD
James McCormack, PharmD
Christina Korownyk, MD
Publication date
01-11-2016
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 11/2016
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-016-3699-x

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