Published in:
01-05-2016 | Editorial
Vitamin D-binding protein: one more piece in the puzzle of acromegalic osteopathy?
Authors:
G. Mazziotti, F. Maffezzoni, A. Giustina
Published in:
Endocrine
|
Issue 2/2016
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Excerpt
In only 5 years, more than 20,000 papers (more than 300 in the last month) dealing with vitamin D have been published, reflecting the deep interest of the scientific community for the role of this hormone in health and disease. As a matter of fact, vitamin D has been shown to exert pleiotropic effects on different tissues and there has been growing evidence that low vitamin D may be associated with several pathological conditions, including fragility fractures [
1], myopathy [
2], diabetes [
3], cardiovascular [
4], autoimmune [
5], and neoplastic diseases [
6]. Despite this compelling evidence, there is still controversy on how hypovitaminosis D should be evaluated and defined in different clinical settings and whether and how supplementation of vitamin D deficiency may truly influence the different clinical outcomes. …
