Published in:
Open Access
01-12-2020 | Research
Vital-sign circadian rhythms in patients prior to discharge from an ICU: a retrospective observational analysis of routinely recorded physiological data
Authors:
Shaun Davidson, Mauricio Villarroel, Mirae Harford, Eoin Finnegan, Joao Jorge, Duncan Young, Peter Watkinson, Lionel Tarassenko
Published in:
Critical Care
|
Issue 1/2020
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Excerpt
Patient care in an intensive care unit (ICU) typically involves maintaining homeostasis or ‘normalisation’ of vital signs [
1‐
3], where the body is unable to provide this for itself. However, the process of controlling and regulating vital signs, combined with sedation, inflammation, environmental light, and noise levels, can disrupt a patient’s natural circadian rhythms [
4]. ICU practice in general does not emphasise support of a patient’s circadian rhythms, though there is a growing desire to improve upon this [
5]. Chronically disrupted circadian rhythms are associated with metabolic disorders such as obesity and diabetes, cardiovascular disease, and cancer [
6‐
9]. In an ICU, disruption or loss of a patient’s circadian rhythms is associated with complications such as immune system disruption [
10], delirium [
11,
12], and mortality [
13,
14]. …