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Published in: European Journal of Clinical Microbiology & Infectious Diseases 12/2018

01-12-2018 | Review

Viral infection and atherosclerosis

Authors: Nima Hemmat, Amin Ebadi, Reza Badalzadeh, Mohammad Yousef Memar, Hossein Bannazadeh Baghi

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 12/2018

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Abstract

Several risk factors have been described for the pathogenesis of atherosclerosis. Infectious diseases are suggested to be a causative factor, and some viruses have been studied for their relation with atherosclerotic diseases. Studies report two hypotheses, direct and indirect effects, for the role of viral infections in atherogenesis. Viruses are able to initiate atherosclerosis by two different pathways. They can exert their direct effects on atherogenesis by infecting vascular cells and then inducing inflammation in the endothelium and smooth muscle cells. Alternatively, they can also apply indirect effects by infecting non-vascular cells and inducing systemic inflammation. In this review, we consider the available data about the effects and correlations of DNA and RNA viruses on atherosclerosis.
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Metadata
Title
Viral infection and atherosclerosis
Authors
Nima Hemmat
Amin Ebadi
Reza Badalzadeh
Mohammad Yousef Memar
Hossein Bannazadeh Baghi
Publication date
01-12-2018
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 12/2018
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-018-3370-z

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