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Published in: Pediatric Cardiology 5/2005

01-10-2005

Ventricular Tachycardia in a Neonate with Prenatally Diagnosed Cardiac Tumors: A Case with Tuberous Sclerosis

Authors: Y. Hirakubo, K. Ichihashi, H. Shiraishi, M. Y. Momoi

Published in: Pediatric Cardiology | Issue 5/2005

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Abstract

We report a patient with prenatally diagnosed tuberous sclerosis. Fetal ultrasonography demostrated multiple cardiac tumors and arrhythmia. After birth, because of frequent supraventricular extrasystoles, the infant was admitted to the neonatal intensive care unit. Findings on 24-hour ambulatory electrocardiogram (ECG) showed frequent supraventricular tachycardia and ventricular tachycardia with four beats as the longest run. At the age of 12 days, he developed cardiopulmonary arrest after crying out. A monitored ECG showed ventricular tachycardia. Twenty minutes after onset, a 12-lead ECG showed ventricular fibrillation, which returned to normal sinus rhythm with repeated DC cardioversion. Oral antiarrhythmic therapy with carteolol hydrochloride was effective. The patient showed no further symptoms after oral medication was initiated and the tumors regressed spontaneously.
Literature
1.
go back to reference Alkalay, AL, Ferry, DA, Lin, B, Fink, BW, Pomerance, JJ 1987Spontaneous regression of cardiac rhabdomyoma in tuberous sclerosisClin Pediatr26532535 Alkalay, AL, Ferry, DA, Lin, B, Fink, BW, Pomerance, JJ 1987Spontaneous regression of cardiac rhabdomyoma in tuberous sclerosisClin Pediatr26532535
2.
go back to reference Bosi, G, Lintermans, JP, Pellegrino, PA, Svaluto-Moreolo, G, Vliers, A 1996The natural history of cardiac rhabdomyoma with and without tuberous sclerosisActa Paediatr85928931PubMed Bosi, G, Lintermans, JP, Pellegrino, PA, Svaluto-Moreolo, G, Vliers, A 1996The natural history of cardiac rhabdomyoma with and without tuberous sclerosisActa Paediatr85928931PubMed
3.
go back to reference Bouillon, T, Schiffmann, H, Bartmus, D, Gundert-Remy, U 1996Aniodarone in a newborn with ventricular tachycardia and a intracardiac tumor: adjusting the dose according to an individualized dosing regimenPediatr Cardiol17112114PubMedCrossRef Bouillon, T, Schiffmann, H, Bartmus, D, Gundert-Remy, U 1996Aniodarone in a newborn with ventricular tachycardia and a intracardiac tumor: adjusting the dose according to an individualized dosing regimenPediatr Cardiol17112114PubMedCrossRef
4.
go back to reference Byard, RW, Blumbergs, PC, James, RA 2003Mechanisms of unexpected death in tuberous sclerosisJ Forensic Sci48172176PubMed Byard, RW, Blumbergs, PC, James, RA 2003Mechanisms of unexpected death in tuberous sclerosisJ Forensic Sci48172176PubMed
5.
go back to reference Case, CL, Gillette, PC, Crawford, FA 1991Cardiac rhabdomyomas causing supraventricular and lethal ventricular arrhythmias in an infantAm Heart J12214841486PubMedCrossRef Case, CL, Gillette, PC, Crawford, FA 1991Cardiac rhabdomyomas causing supraventricular and lethal ventricular arrhythmias in an infantAm Heart J12214841486PubMedCrossRef
6.
go back to reference Choi, JM, Jaffe, R, Maidman, J, Baxi, LV 2000Multiple cardiac rhabdomyomas detected in uteroFetal Diagn Ther15174176PubMedCrossRef Choi, JM, Jaffe, R, Maidman, J, Baxi, LV 2000Multiple cardiac rhabdomyomas detected in uteroFetal Diagn Ther15174176PubMedCrossRef
7.
go back to reference Enbergs, A, Borggrefe, M, Kurlemann, G, et al. 1996Ventricular tachycardia caused by cardiac rhabdomyoma in a young adult with tuberous sclerosisAm Heart J13212631265PubMedCrossRef Enbergs, A, Borggrefe, M, Kurlemann, G,  et al. 1996Ventricular tachycardia caused by cardiac rhabdomyoma in a young adult with tuberous sclerosisAm Heart J13212631265PubMedCrossRef
8.
go back to reference Engle, MA, Ebert, PA, Redo, SF 1974Recurrent ventricular tachycardia due to respectable cardiac tumorCirculation5010521057PubMed Engle, MA, Ebert, PA, Redo, SF 1974Recurrent ventricular tachycardia due to respectable cardiac tumorCirculation5010521057PubMed
9.
go back to reference Freedom, RM, Lee, LJ, MacDonald, C, Tailor, G 2000Selected aspects of cardiac tumors in infancy and childhoodPediatr Cardiol21299316PubMedCrossRef Freedom, RM, Lee, LJ, MacDonald, C, Tailor, G 2000Selected aspects of cardiac tumors in infancy and childhoodPediatr Cardiol21299316PubMedCrossRef
10.
go back to reference Groves, AM, Fagg, NL, Cook, AC, Allan, LD 1992Cardiac tumors in intrauterine lifeArch Dis Child6711891192PubMed Groves, AM, Fagg, NL, Cook, AC, Allan, LD 1992Cardiac tumors in intrauterine lifeArch Dis Child6711891192PubMed
11.
go back to reference Holley, DG, Martin, GR, Brenner, JI, et al. 1995Diagnosis and management of fetal cardiac tumors; a multicenter experience and review of published reportsJ Am Coll Cardio26516520 Holley, DG, Martin, GR, Brenner, JI,  et al. 1995Diagnosis and management of fetal cardiac tumors; a multicenter experience and review of published reportsJ Am Coll Cardio26516520
12.
go back to reference Kohli, V, Mangru, N, Pearse, LA, Cantwell, P, Young, ML 1996Radiofrequency ablation of ventricular tachycardia in an infant with cardiac tumorsAm Heart J132198200PubMedCrossRef Kohli, V, Mangru, N, Pearse, LA, Cantwell, P, Young, ML 1996Radiofrequency ablation of ventricular tachycardia in an infant with cardiac tumorsAm Heart J132198200PubMedCrossRef
13.
go back to reference Mas, C, Penny, DJ, Menahem, S 2000Pre-excitation syndrome secondary to cardiac rhabdomyomas in tuberous sclerosisJ Paediatr Child Health368486PubMedCrossRef Mas, C, Penny, DJ, Menahem, S 2000Pre-excitation syndrome secondary to cardiac rhabdomyomas in tuberous sclerosisJ Paediatr Child Health368486PubMedCrossRef
14.
go back to reference Muhler, EG, Kienast, W, Turniski-Harder, V, Bernuth, G 1994Arrhythmias in infants and children with primary cardiac tumorsEur Heart J15915921PubMed Muhler, EG, Kienast, W, Turniski-Harder, V, Bernuth, G 1994Arrhythmias in infants and children with primary cardiac tumorsEur Heart J15915921PubMed
15.
go back to reference Muhler, EG, Turniski-Harder, V, Engelhardt, W, Bernuth, G 1994Cardiac involvement in tuberous sclerosisBr Heart J72584590PubMed Muhler, EG, Turniski-Harder, V, Engelhardt, W, Bernuth, G 1994Cardiac involvement in tuberous sclerosisBr Heart J72584590PubMed
16.
go back to reference Nir, A, Tajik, AJ, Freeman, WK, et al. 1995Tuberous sclerosis and cardiac rhabdomyomaAm J Cardiol76419421PubMedCrossRef Nir, A, Tajik, AJ, Freeman, WK,  et al. 1995Tuberous sclerosis and cardiac rhabdomyomaAm J Cardiol76419421PubMedCrossRef
17.
go back to reference O'Callaghan, FJK, Clarke, AC, Joffe, H, et al. 1998Tuberous sclerosis complex and Wolf–Parkinson–White syndromeArch Dis Child78159162PubMedCrossRef O'Callaghan, FJK, Clarke, AC, Joffe, H,  et al. 1998Tuberous sclerosis complex and Wolf–Parkinson–White syndromeArch Dis Child78159162PubMedCrossRef
18.
go back to reference Piptone, S, Mongiovi, M, Grillo, R, Gagliano, S, Sperandeo, V 2002Cardiac rhabdomyoma in intrauterine life: clinical features and natural history. A case series and review of published reportsItal Heart J34852 Piptone, S, Mongiovi, M, Grillo, R, Gagliano, S, Sperandeo, V 2002Cardiac rhabdomyoma in intrauterine life: clinical features and natural history. A case series and review of published reportsItal Heart J34852
19.
go back to reference Shiraishi, H, Yanagisawa, M, Kuramatsu, T, Shimoizumi, H, Tanaka, O 1988Cardiac tumor in a neonate with tuberous sclerosis: echocardiographic demostration and magnetic resonance imagingEur J Pediatr1485052PubMedCrossRef Shiraishi, H, Yanagisawa, M, Kuramatsu, T, Shimoizumi, H, Tanaka, O 1988Cardiac tumor in a neonate with tuberous sclerosis: echocardiographic demostration and magnetic resonance imagingEur J Pediatr1485052PubMedCrossRef
20.
go back to reference Valdes-Dapena, M, Gilbert-Barness, E 2002Cardiovascular causes for sudden infant deathPediatr Pathol Mol Med21195211PubMed Valdes-Dapena, M, Gilbert-Barness, E 2002Cardiovascular causes for sudden infant deathPediatr Pathol Mol Med21195211PubMed
21.
go back to reference Zeigler, VI, Gillette, PC, Crawford, FA, Wiles, HB, Fyfe, DA 1990New approaches to treatment of incessant ventricular tachycardia in the very youngJ Am Coll Cardiol16681685PubMedCrossRef Zeigler, VI, Gillette, PC, Crawford, FA, Wiles, HB, Fyfe, DA 1990New approaches to treatment of incessant ventricular tachycardia in the very youngJ Am Coll Cardiol16681685PubMedCrossRef
Metadata
Title
Ventricular Tachycardia in a Neonate with Prenatally Diagnosed Cardiac Tumors: A Case with Tuberous Sclerosis
Authors
Y. Hirakubo
K. Ichihashi
H. Shiraishi
M. Y. Momoi
Publication date
01-10-2005
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 5/2005
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-004-0714-5

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