Published in:
02-02-2024 | Vasovagal Syncope | Letter to the Editor
What lies beneath: cyclical giant bursts of SNA during vasovagal syncope
Author:
D. L. Jardine
Published in:
Clinical Autonomic Research
|
Issue 1/2024
Login to get access
Excerpt
Rapid sympathetic control of vasoconstriction, modulated by baroreflex feed-back, is essential for the maintenance of blood pressure (BP) during exercise, postural change and hypovolemia [
1]. During vasovagal syncope (VVS), the baroreflexes fail and most recordings show bradycardia with decreased frequency of muscle sympathetic nerve activity (MSNA) [
2]. The fall in MSNA is probably secondary to decreased generation of sympathetic nerve activity (SNA) in the rostral ventrolateral medulla which is resolves as blood pressure recovers and baroreflex function returns. Any SNA observed during VVS may be driven by other (non-baroreflex) pathways in the brainstem. …