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Published in: Antimicrobial Resistance & Infection Control 1/2020

01-12-2020 | Vancomycin | Research

A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit

Authors: Ronella Marom, Dror Mandel, Alon Haham, Irit Berger, Amit Ovental, Craig Raskind, Galia Grisaru-Soen, Amos Adler, Jonathan Lellouche, David Schwartz, Yehuda Carmeli, Vered Schechner

Published in: Antimicrobial Resistance & Infection Control | Issue 1/2020

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Abstract

Objective

To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU).

Methods

Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients.

Results

A newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified.

Conclusion

Our study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU’s routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.
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Metadata
Title
A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit
Authors
Ronella Marom
Dror Mandel
Alon Haham
Irit Berger
Amit Ovental
Craig Raskind
Galia Grisaru-Soen
Amos Adler
Jonathan Lellouche
David Schwartz
Yehuda Carmeli
Vered Schechner
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Vancomycin
Published in
Antimicrobial Resistance & Infection Control / Issue 1/2020
Electronic ISSN: 2047-2994
DOI
https://doi.org/10.1186/s13756-020-00755-0

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