Published in:
Open Access
01-02-2011 | Poster presentation
Validation of the AKIN criteria definition using high-resolution ICU data from the MIMIC-II database
Authors:
T Mandelbaum, DJ Scott, J Lee, RG Mark, MD Howell, A Malhotra, D Talmor
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
Recently the Acute Kidney Injury (AKI) Network proposed criteria for the definition of AKI in the critically ill. The minimum hourly urine output rate used to define oliguria (< 0.5 ml/kg/hour) is based exclusively on clinical experience and animal models, not on clinical investigation. Moreover, the minimum duration of oliguria (6 hours) is based on clinical experience and was never experimentally determined. We used a massive database of ICU patients (MIMIC) to continuously vary the observation period and threshold of urine output measurements to determine optimal AKI definitions for improved in-hospital mortality prediction. …