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01-08-2021 | Vaccination | Original Paper

Perceptions and Knowledge About the MenB Vaccine Among Parents of High School Students

Authors: Eric Richardson, Kathleen A. Ryan, Robert M. Lawrence, Christopher A. Harle, Alyson Young, Melvin D. Livingston, Amit Rawal, Stephanie A. S. Staras

Published in: Journal of Community Health | Issue 4/2021

Abstract

Serogroup B meningococcal disease (MenB) causes almost 60% of meningitis cases among adolescents and young adults. Yet, MenB vaccine coverage among adolescents remains below 10%. Since parents are the primary medical decision makers for adolescents, we examined MenB vaccination rates and parent attitudes about meningitis and the MenB vaccine. In 2018, in conjunction with a county-wide, school-based immunization campaign, we conducted a mixed methods study among parents of 16- to 17-year-olds. We facilitated focus groups asking parents about their knowledge of meningitis and reactions to educational materials and sent behavioral surveys based on Health Belief Model constructs to parents through the county high school system. Parents in three focus groups (n = 8; participation rate = 13%) expressed confusion about their child’s need to receive the MenB vaccine in addition to the meningococcal conjugate vaccine (MenACWY), but conveyed strong trust in their physicians’ recommendation. Among survey participants (n = 170), 70 (41%) had heard of the MenB vaccine. Among those 70 parents, the most common barriers to vaccination were concerns about side effects (55%) and uncertainty of susceptibility due to receipt of the MenACWY vaccine (30%). The percentage of teens that received at least one dose of the MenB vaccine was 50% (n = 35) by parent report and 23% (n = 16) by state vaccination records. Parents demonstrated uncertainty and confusion about the MenB vaccine particularly due to the existence of another meningitis vaccine and limited health care provider recommendations. Confirmatory studies of parent confusion about the MenB vaccine are needed to develop interventions.

MacNeil, J. R., Blain, A. E., Wang, X., & Cohn, A. C. (2017). Current epidemiology and trends in meningococcal disease—United States, 1996–2015. Clinical Infectious Diseases, 66(8), 1276–1281. https://doi.org/10.1093/cid/cix993.CrossRef

Mbaeyi, S. A., Joseph, S. J., Blain, A., Wang, X., Hariri, S., & MacNeil, J. R. (2019). Meningococcal disease among college-aged young adults: 2014–2016. Pediatrics, 143(1), e20182130. https://doi.org/10.1542/peds.2018-2130.CrossRefPubMed

Mbaeyi, S. A., Blain, A., Whaley, M. J., Wang, X., Cohn, A. C., & MacNeil, J. R. (2018). Epidemiology of meningococcal disease outbreaks in the United States, 2009–2013. Clinical Infectious Diseases, 68(4), 580–585. https://doi.org/10.1093/cid/ciy548.CrossRef

Wang, B., Santoreneos, R., Giles, L., Afzali, H. H., & Marshall, H. (2019). Case fatality rates of invasive meningococcal disease by serogroup and age: A systematic review and meta-analysis. Vaccine, 37(21), 2768–2782. https://doi.org/10.1016/j.vaccine.2019.04.020.CrossRefPubMed

Burman, C., Serra, L., Nuttens, C., Presa, J., Balmer, P., & York, L. (2019). Meningococcal disease in adolescents and young adults: A review of the rationale for prevention through vaccination. Human Vaccines & Immunotherapeutics, 15(2), 459–469. https://doi.org/10.1080/21645515.2018.1528831.CrossRef

Patton, M. E., Stephens, D., Moore, K., & MacNeil, J. R. (2017). Updated recommendations for use of MenB-FHbp serogroup B meningococcal vaccine—advisory committee on immunization practices, 2016. Morbidity and Mortality Weekly Report, 66(19), 509–513. https://doi.org/10.15585/mmwr.mm6619a6.CrossRefPubMedPubMedCentral

Elam-Evans, L. D., Yankey, D., Singleton, J. A., Sterrett, N., Markowitz, L. E., Williams, C. L., et al. (2020). National, regional, state, and selected local area vaccination coverage among adolescents aged 13–17 years—United States, 2019. MMWR: Morbidity and Mortality Weekly Report, 69(33), 1109–1116. https://doi.org/10.15585/mmwr.mm6933a1.CrossRefPubMedPubMedCentral

McRee, A. L., Reiter, P. L., & Brewer, N. T. (2010). Vaccinating adolescent girls against human papillomavirus-who decides? Preventive Medicine, 50(4), 213–214. https://doi.org/10.1016/j.ypmed.2010.02.001.CrossRefPubMedPubMedCentral

Jackson, C., Yarwood, J., Saliba, V., & Bedford, H. (2017). UK parents’ attitudes towards meningococcal group B (MenB) vaccination: A qualitative analysis. British Medical Journal Open, 7(4), e012851. https://doi.org/10.1136/bmjopen-2016-012851.CrossRef

10.

Mameli, C., Faccini, M., Mazzali, C., Picca, M., Colella, G., Duca, P. G., et al. (2014). Acceptability of meningococcal serogroup B vaccine among parents and health care workers in Italy: A survey. Human Vaccines & Immunotherapeutics, 10(10), 3004–3010. https://doi.org/10.4161/21645515.2014.971602.CrossRef

11.

Marshall, H., Clarke, M., & Sullivan, T. (2014). Parental and community acceptance of the benefits and risks associated with meningococcal B vaccines. Vaccine, 32(3), 338–344. https://doi.org/10.1016/j.vaccine.2013.11.042.CrossRefPubMed

12.

Morrone, T., Napolitano, F., Albano, L., & Di Giuseppe, G. (2017). Meningococcal serogroup B vaccine: Knowledge and acceptability among parents in Italy. Human Vaccines & Immunotherapeutics, 13(8), 1921–1927. https://doi.org/10.1080/21645515.2017.1313940.CrossRef

13.

Basta, N. E., Becker, A. B., Li, Q., & Nederhoff, D. (2019). Parental awareness of meningococcal B vaccines and willingness to vaccinate their teens. Vaccine, 37(4), 670–676. https://doi.org/10.1016/j.vaccine.2018.11.078.CrossRefPubMed

14.

Srivastava, A., Dempsey, A., Galitsky, A., Fahimi, M., & Huang, L. (2020). Parental awareness and utilization of meningococcal serogroup B vaccines in the United States. BMC Public Health, 20(1), 1109. https://doi.org/10.1186/s12889-020-09181-8.CrossRefPubMedPubMedCentral

15.

Brewer, N. T., Chapman, G. B., Gibbons, F. X., Gerrard, M., McCaul, K. D., & Weinstein, N. D. (2007). Meta-analysis of the relationship between risk perception and health behavior: The example of vaccination. Health Psychology, 26(2), 136–145. https://doi.org/10.1037/0278-6133.26.2.136.CrossRefPubMed

16.

Brewer, N. T., & Fazekas, K. I. (2007). Predictors of HPV vaccine acceptability: A theory-informed, systematic review. Preventive Medicine, 45(2), 107–114. https://doi.org/10.1016/j.ypmed.2007.05.013.CrossRefPubMed

17.

Dorell, C., Yankey, D., Kennedy, A., & Stokley, S. (2013). Factors that influence parental vaccination decisions for adolescents, 13 to 17 years old: National immunization survey-teen, 2010. Clinical Pediatrics, 52(2), 162–170. https://doi.org/10.1177/0009922812468208.CrossRefPubMed

18.

Glanz, K., Rimer, B. K., & Viswanath, K. (2008). Health behavior and health education: Theory, research, and practice. Hoboken: Wiley.

19.

Staras, S. A. S., Vadaparampil, S. T., Patel, R. P., & Shenkman, E. A. (2014). Parent perceptions important for HPV vaccine initiation among low income adolescent girls. Vaccine, 32(46), 6163–6169. https://doi.org/10.1016/j.vaccine.2014.08.054.CrossRefPubMedPubMedCentral

20.

Iafrate, R. P., Lipori, G. P., Harle, C. A., Nelson, D. R., Barnash, T. J., Leebove, P. T., et al. (2016). Consent2Share: An integrated broad consenting process for re-contacting potential study subjects. Journal of Clinical and Translational Research, 2(4), 113–122.CrossRef

21.

Centers for Disease Control and Prevention. (2019). Meningococcal B Vaccine: What you need to know. Retrieved October 13, 2020 from https://www.cdc.gov/vaccines/hcp/vis/vis-statements/mening-serogroup.pdf.

22.

Centers for Disease Control and Prevention. (2019). Meningococcal Vaccination: What everyone should know. Retrieved October 13, 2020 from https://www.cdc.gov/vaccines/vpd/mening/public/index.html.

23.

National Foundation for Infectious Diseases (2019) Meningococcal disease: Focus in serogroup B. Retrieved October 13, 2020 from https://www.nfid.org/infectious-diseases/meningococcal-disease-focus-on-serogroup-b/.

24.

Nvivo Qualitative Data Analysis Software [computer program]. (2018). Version 12: QSR International Pty Ltd.

25.

Kuckartz, U. (2019). Qualitative text analysis: A systematic approach. In G. Kaiser & N. Presmeg (Eds.), Compendium for early career researchers in mathematics education (pp. 181–197). Cham: Springer.CrossRef

26.

Harris, P. A., Taylor, R., Minor, B. L., Elliott, V., Fernandez, M., O’Neal, L., et al. (2019). The REDCap consortium: Building an international community of software platform partners. Journal of Biomedical Informatics, 95, 103208. https://doi.org/10.1016/j.jbi.2019.103208.CrossRefPubMedPubMedCentral

27.

Harris, P. A., Taylor, R., Thielke, R., Payne, J., Gonzalez, N., & Conde, J. G. (2009). Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. Journal of Biomedical Informatics, 42(2), 377–381. https://doi.org/10.1016/j.jbi.2008.08.010.CrossRefPubMed

28.

Health Resources and Services Administration. (2018). National survey of Children’s Heath Questionnaire. Retrieved October 13, 2020 from https://www.childhealthdata.org/learn-about-the-nsch/surveyinstruments.

29.

MacDougall, D. M., Halperin, B. A., Langley, J. M., MacKinnon-Cameron, D., Li, L., & Halperin, S. A. (2016). Knowledge, attitudes, beliefs, and behaviors of parents and healthcare providers before and after implementation of a universal rotavirus vaccination program. Vaccine, 34(5), 687–695. https://doi.org/10.1016/j.vaccine.2015.09.089.CrossRefPubMed

30.

National Cancer Center. (2014). Health Information National Trends Survey. Retrieved October 13, 2020 from https://hints.cancer.gov/data/survey-instruments.aspx.

31.

Centers for Disease Control and Prevention. (2011). Updated recommendations for use of meningococcal conjugate vaccines—Advisory Committee on Immunization Practices (ACIP), 2010. Morbidity and Mortality Weekly Report, 60(3), 72–76.

32.

Rosenthal, S. L., Weiss, T. W., Zimet, G. D., Ma, L., Good, M. B., & Vichnin, M. D. (2011). Predictors of HPV vaccine uptake among women aged 19–26: Importance of a physician’s recommendation. Vaccine, 29(5), 890–895. https://doi.org/10.1016/j.vaccine.2009.12.063.CrossRefPubMed

33.

Florida Department of Health Division of Disease Control and Health Protection Bureau of Communicable Disease Immunization Section. (2019). FL SHOTS TM. Retrieved October 13, 2020 from https://www.flshotsusers.com/.

34.

Kennedy, A., Stokley, S., Curtis, C. R., & Gust, D. (2012). Limited awareness of vaccines recommended for adolescents and other results from two national consumer health surveys in the United States. Journal of Adolescent Health, 50(2), 198–200. https://doi.org/10.1016/j.jadohealth.2011.04.017.CrossRef

35.

Wong, C. A., Taylor, J. A., Wright, J. A., Opel, D. J., & Katzenellenbogen, R. A. (2013). Missed opportunities for adolescent vaccination, 2006–2011. Journal of Adolescent Health, 53(4), 492–497. https://doi.org/10.1016/j.jadohealth.2013.05.009.CrossRef

36.

Hirth, J. M., Fuchs, E. L., Chang, M., Fernandez, M. E., & Berenson, A. B. (2019). Variations in reason for intention not to vaccinate across time, region, and by race/ethnicity, NIS-teen (2008–2016). Vaccine, 37(4), 595–601. https://doi.org/10.1016/j.vaccine.hesitancy.CrossRefPubMed

37.

Roberts, J. R., Thompson, D., Rogacki, B., Hale, J. J., Jacobson, R. M., Opel, D. J., et al. (2015). Vaccine hesitancy among parents of adolescents and its association with vaccine uptake. Vaccine, 33(14), 1748–1755. https://doi.org/10.1016/j.vaccine.2015.01.068.CrossRefPubMed

38.

Strelitz, B., Gritton, J., Klein, E. J., Bradford, M. C., Follmer, K., Zerr, D. M., et al. (2015). Parental vaccine hesitancy and acceptance of seasonal influenza vaccine in the pediatric emergency department. Vaccine, 33(15), 1802–1807. https://doi.org/10.1016/j.vaccine.2015.02.034.CrossRefPubMedPubMedCentral

39.

Williams, S. E. (2014). What are the factors that contribute to parental vaccine-hesitancy and what can we do about it? Human Vaccines & Immunotherapeutics, 10(9), 2584–2596. https://doi.org/10.4161/hv.28596.CrossRef

40.

Dorell, C., Yankey, D., & Strasser, S. (2011). Parent-reported reasons for nonreceipt of recommended adolescent vaccinations, national immunization survey: Teen, 2009. Clinical Pediatrics (Phila), 50(12), 1116–1124. https://doi.org/10.1177/0009922811415104.CrossRef

41.

Dorell, C. G., Jain, N., & Yankey, D. (2011). Validity of parent-reported vaccination status for adolescents aged 13–17 years: National immunization survey-teen, 2008. Public Health Reports, 126(2_suppl), 60–69. https://doi.org/10.1177/00333549111260s208.CrossRefPubMedPubMedCentral

42.

Stupiansky, N. W., Zimet, G. D., Cummings, T., Fortenberry, J. D., & Shew, M. (2012). Accuracy of self-reported human papillomavirus vaccine receipt among adolescent girls and their mothers. Journal of Adolescent Health, 50(1), 103–105. https://doi.org/10.1016/j.jadohealth.2011.04.010.CrossRef

43.

Kempe, A., Allison, M. A., MacNeil, J. R., O’Leary, S. T., Crane, L. A., Beaty, B. L., et al. (2018). Knowledge and attitudes regarding category B ACIP recommendations among primary care providers for children. Academic Pediatrics, 18(7), 763–768. https://doi.org/10.1016/j.acap.2018.04.005.CrossRefPubMedPubMedCentral

44.

Kempe, A., Allison, M. A., MacNeil, J. R., O’Leary, S. T., Crane, L. A., Beaty, B. L., et al. (2018). Adoption of serogroup B meningococcal vaccine recommendations. Pediatrics, 142(3), e20180344. https://doi.org/10.1542/peds.2018-0344.CrossRefPubMed

45.

Gargano, L. M., Herbert, N. L., Painter, J. E., Sales, J. M., Morfaw, C., Rask, K., et al. (2013). Impact of a physician recommendation and parental immunization attitudes on receipt or intention to receive adolescent vaccines. Human Vaccines & Immunotherapeutics, 9(12), 2627–2633. https://doi.org/10.4161/hv.25823.CrossRef

46.

Gilkey, M. B., Calo, W. A., Moss, J. L., Shah, P. D., Marciniak, M. W., & Brewer, N. T. (2016). Provider communication and HPV vaccination: The impact of recommendation quality. Vaccine, 34(9), 1187–1192. https://doi.org/10.1016/j.vaccine.2016.01.023.CrossRefPubMedPubMedCentral

47.

Lu, P.-J., Yankey, D., Jeyarajah, J., O’Halloran, A., Meyer, S. A., Elam-Evans, L. D., et al. (2017). Impact of provider recommendation on Tdap vaccination of adolescents aged 13–17 years. American Journal of Preventive Medicine, 53(3), 373–384. https://doi.org/10.1016/j.amepre.2017.03.022.CrossRefPubMedPubMedCentral

Title: Perceptions and Knowledge About the MenB Vaccine Among Parents of High School Students
Authors: Eric Richardson
Kathleen A. Ryan
Robert M. Lawrence
Christopher A. Harle
Alyson Young
Melvin D. Livingston
Amit Rawal
Stephanie A. S. Staras
Publication date: 01-08-2021
Publisher: Springer US
Keywords: Vaccination
Meningitis
Published in: Journal of Community Health / Issue 4/2021
Print ISSN: 0094-5145
Electronic ISSN: 1573-3610
DOI: https://doi.org/10.1007/s10900-020-00954-1

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Perceptions and Knowledge About the MenB Vaccine Among Parents of High School Students

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Keynote webinar | Spotlight on medication adherence

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