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BMC Public Health
Published in: BMC Public Health 1/2022

Open Access 01-12-2022 | Vaccination | Research

Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020

Authors: Hongxia Peng, Zhenhua Chen, Lin Cai, Juan Liao, Ke Zheng, Shuo Li, Xueling Ren, Xiaoxia Duan, Xueqin Tang, Xiao Wang, Lu Long, Chunxia Yang

Published in: BMC Public Health | Issue 1/2022

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Abstract

Background

Meteorological factors and air pollutants have been reported to be associated with hand, foot, and mouth disease (HFMD) epidemics before the introduction of vaccine. However, there is limited evidence for studies with long-term dimensions.

Methods

We collected the daily HFMD counts, weather and air pollution data from 2014 to 2020 in Chengdu. Distributed lag non-linear models (DLNM) were used to assess the associations of meteorological factors and air pollutants on HFMD cases.

Results

From 2014–2020, high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD. In pre-vaccination period, extreme high and low temperatures, PM10 and NO2, low precipitation and high concentrations of PM2.5 and O3 significantly increase the risk of HFMD; In post-vaccination period, high relative humidity and low level of CO can significantly increase the incidence of HFMD; During the period of COVID-19, only low temperature will significantly increase the risk of HFMD; Low concentration of air pollutants has the greatest impact on the 6–14 age group, while the high concentration of air pollutants has the greatest impact on the 0–1 age group.

Conclusions

Our study suggest that high relative humidity and precipitation and extremely high and low levels of PM10, O3, SO2 and CO increased the risk of HFMD from 2014 to 2020. The results of this study provide a reference for local authorities to formulate intervention measures and establish an environment-based disease early warning system.
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Metadata
Title
Relationship between meteorological factors, air pollutants and hand, foot and mouth disease from 2014 to 2020
Authors
Hongxia Peng
Zhenhua Chen
Lin Cai
Juan Liao
Ke Zheng
Shuo Li
Xueling Ren
Xiaoxia Duan
Xueqin Tang
Xiao Wang
Lu Long
Chunxia Yang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2022
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-022-13365-9

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