Published in:
01-12-2020 | Uveitis | Viewpoint
Uveitis in juvenile idiopathic arthritis
Authors:
Ross E. Petty, Qi Zheng
Published in:
World Journal of Pediatrics
|
Issue 6/2020
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Excerpt
Uveitis is an intraocular inflammation with potentially sight-threatening consequences. Chronic anterior uveitis is a common extra-articular manifestation of juvenile idiopathic arthritis (JIA). It affects predominantly the iris and ciliary body [
1]. Less commonly there are cells in the vitreous (intermediate uveitis) or there may occasionally be panuveitis when inflammation involves the anterior chamber, vitreous, and retina and/or choroid, sometimes with cystoid macular edema [
2]. The reported incidence of uveitis in JIA overall is about 13% [
3‐
5]. The frequency of uveitis is strongly related to the type of JIA. Oligoarthritis is the most common type of JIA associated with childhood uveitis (30%), followed by polyarthritis rheumatoid factor (RF)-negative (20%) and psoriatic arthritis (10%) [
6]. Chronic anterior uveitis almost never occurs in children with systemic onset JIA or rheumatoid factor-positive polyarticular JIA. Acute (symptomatic) anterior uveitis occurs in enthesitis related arthritis (ERA) [
5]. …