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Published in: BMC Oral Health 1/2023

Open Access 01-12-2023 | Research

Using machine learning to determine age over 16 based on development of third molar and periodontal ligament of second molar

Authors: Shihui Shen, Zhuojun Zhou, Jian Wang, Linfeng Fan, Junli Han, Jiang Tao

Published in: BMC Oral Health | Issue 1/2023

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Abstract

Background

Having a reliable and feasible method to estimate whether an individual has reached 16 years of age would greatly benefit forensic analysis. The study of age using dental information has matured recently. In addition, machine learning (ML) is gradually being applied for dental age estimation.

Aim

The purpose of this study was to evaluate the development of the third molar using the Demirjian method (Demirjian3M), measure the development index of the third molar (I3M) using the method by Cameriere, and assess the periodontal ligament development of the second molar (PL2M). This study aimed to predict whether Chinese adolescents have reached the age of criminal responsibility (16 years) by combining the above measurements with ML techniques.

Subjects & methods

A total of 665 Chinese adolescents aged between 12 and 20 years were recruited for this study. The development of the second and third molars was evaluated by taking orthopantomographs. ML algorithms, including random forests (RF), decision trees (DT), support vector machines (SVM), K-nearest neighbours (KNN), Bernoulli Naive Bayes (BNB), and logistic regression (LR), were used for training and testing to determine the dental age. This is the first study to combine ML with an evaluation of periodontal ligament and tooth development to predict whether individuals are over 16 years of age.

Results and conclusions

The study showed that SVM had the highest Bayesian posterior probability at 0.917 and a Youden index of 0.752. This finding provides an important reference for forensic identification, and the combination of traditional methods and ML is expected to improve the accuracy of age determination for this population, which is of substantial significance for criminal litigation.
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Literature
1.
go back to reference Bagherian A, Sadeghi M. Assessment of dental maturity of children aged 3.5 to 13.5 years using the Demirjian method in an Iranian population. J Oral Sci. 2011;53(1):37–42.CrossRefPubMed Bagherian A, Sadeghi M. Assessment of dental maturity of children aged 3.5 to 13.5 years using the Demirjian method in an Iranian population. J Oral Sci. 2011;53(1):37–42.CrossRefPubMed
2.
go back to reference Willems G, Van Olmen A, Spiessens B, Carels C. Dental age estimation in belgian children: Demirjian’s technique revisited. J Forensic Sci. 2001;46(4):893–5.CrossRefPubMed Willems G, Van Olmen A, Spiessens B, Carels C. Dental age estimation in belgian children: Demirjian’s technique revisited. J Forensic Sci. 2001;46(4):893–5.CrossRefPubMed
3.
go back to reference Sobieska E, Fester A, Nieborak M, Zadurska M. Assessment of the dental age of children in the polish population with comparison of the Demirjian and the willems methods. Med Sci Monit. 2018;24:8315–21.CrossRefPubMedPubMedCentral Sobieska E, Fester A, Nieborak M, Zadurska M. Assessment of the dental age of children in the polish population with comparison of the Demirjian and the willems methods. Med Sci Monit. 2018;24:8315–21.CrossRefPubMedPubMedCentral
4.
go back to reference Alghali R, Kamaruddin AF, Mokhtar N. Dental age estimation: Comparison of reliability between Malay formula of Demirjian method and Malay formula of Cameriere method. AIP Conf Proc. 2016;1791. Alghali R, Kamaruddin AF, Mokhtar N. Dental age estimation: Comparison of reliability between Malay formula of Demirjian method and Malay formula of Cameriere method. AIP Conf Proc. 2016;1791.
5.
go back to reference Wolf TG, Briseño-Marroquín B, Callaway A, Patyna M, Müller VT, Willershausen I, et al. Dental age assessment in 6- to 14-year old German children: comparison of cameriere and Demirjian methods. BMC Oral Health. 2016;16(1):1–8.CrossRef Wolf TG, Briseño-Marroquín B, Callaway A, Patyna M, Müller VT, Willershausen I, et al. Dental age assessment in 6- to 14-year old German children: comparison of cameriere and Demirjian methods. BMC Oral Health. 2016;16(1):1–8.CrossRef
6.
go back to reference De Luca S, De Giorgio S, Butti AC, Biagi R, Cingolani M, Cameriere R. Age estimation in children by measurement of open apices in tooth roots: study of a Mexican sample. Forensic Sci Int. 2012;221(1–3):155.e1-155.e7.PubMed De Luca S, De Giorgio S, Butti AC, Biagi R, Cingolani M, Cameriere R. Age estimation in children by measurement of open apices in tooth roots: study of a Mexican sample. Forensic Sci Int. 2012;221(1–3):155.e1-155.e7.PubMed
7.
go back to reference Franco A, Thevissen P, Fieuws S, Souza PH, Willems G. Applicability of Willems model for dental age estimations in Brazilian children. Forensic Sci Int. 2013;231(1–3):401 e1-4.PubMed Franco A, Thevissen P, Fieuws S, Souza PH, Willems G. Applicability of Willems model for dental age estimations in Brazilian children. Forensic Sci Int. 2013;231(1–3):401 e1-4.PubMed
8.
go back to reference Apaydin BK, Yasar F. Accuracy of the demirjian, willems and cameriere methods of estimating dental age on Turkish children. Niger J Clin Pract. 2018;21(3):257–63.CrossRefPubMed Apaydin BK, Yasar F. Accuracy of the demirjian, willems and cameriere methods of estimating dental age on Turkish children. Niger J Clin Pract. 2018;21(3):257–63.CrossRefPubMed
9.
go back to reference Dhanjal KS, Bhardwaj MK, Liversidge HM. Reproducibility of radiographic stage assessment of third molars. Forensic Sci Int. 2006;159(1):74–7.CrossRef Dhanjal KS, Bhardwaj MK, Liversidge HM. Reproducibility of radiographic stage assessment of third molars. Forensic Sci Int. 2006;159(1):74–7.CrossRef
10.
go back to reference Gulsahi A, Tirali RE, Cehreli SB, De Luca S, Ferrante L, Cameriere R. The reliability of Cameriere’s method in Turkish children: a preliminary report. Forensic Sci Int. 2015;249:319 e1-5.CrossRefPubMed Gulsahi A, Tirali RE, Cehreli SB, De Luca S, Ferrante L, Cameriere R. The reliability of Cameriere’s method in Turkish children: a preliminary report. Forensic Sci Int. 2015;249:319 e1-5.CrossRefPubMed
11.
go back to reference Cameriere R, Santoro V, Roca R, Lozito P, Introna F, Cingolani M, et al. Assessment of legal adult age of 18 by measurement of open apices of the third molars: study on the Albanian sample. Forensic Sci Int. 2014;245:205.e1-205.e5.CrossRefPubMed Cameriere R, Santoro V, Roca R, Lozito P, Introna F, Cingolani M, et al. Assessment of legal adult age of 18 by measurement of open apices of the third molars: study on the Albanian sample. Forensic Sci Int. 2014;245:205.e1-205.e5.CrossRefPubMed
12.
go back to reference Tafrount C, Galić I, Franchi A, Fanton L, Cameriere R. Third molar maturity index for indicating the legal adult age in southeastern France. Forensic Sci Int. 2019;294:218.e1-218.e6.CrossRefPubMed Tafrount C, Galić I, Franchi A, Fanton L, Cameriere R. Third molar maturity index for indicating the legal adult age in southeastern France. Forensic Sci Int. 2019;294:218.e1-218.e6.CrossRefPubMed
13.
go back to reference De Luca S, Biagi R, Begnoni G, Farronato G, Cingolani M, Merelli V, et al. Accuracy of Cameriere’s cut-off value for third molar in assessing 18 years of age. Forensic Sci Int. 2014;235:102.e1-102.e6.CrossRefPubMed De Luca S, Biagi R, Begnoni G, Farronato G, Cingolani M, Merelli V, et al. Accuracy of Cameriere’s cut-off value for third molar in assessing 18 years of age. Forensic Sci Int. 2014;235:102.e1-102.e6.CrossRefPubMed
14.
go back to reference Sharma P, Wadhwan V, Sharma N. Reliability of determining the age of majority: a comparison between measurement of open apices of third molars and Demirjian stages. J Forensic Odontostomatol. 2018;2(36):2–9. Sharma P, Wadhwan V, Sharma N. Reliability of determining the age of majority: a comparison between measurement of open apices of third molars and Demirjian stages. J Forensic Odontostomatol. 2018;2(36):2–9.
15.
go back to reference Wang J, Bai X, Wang M, Zhou Z, Bian X, Qiu C, et al. Applicability and accuracy of Demirjian and Willems methods in a population of Eastern Chinese subadults. Forensic Sci Int. 2018;292:90–6.CrossRefPubMed Wang J, Bai X, Wang M, Zhou Z, Bian X, Qiu C, et al. Applicability and accuracy of Demirjian and Willems methods in a population of Eastern Chinese subadults. Forensic Sci Int. 2018;292:90–6.CrossRefPubMed
16.
go back to reference Cameriere R, Velandia Palacio LA, Pinares J, Bestetti F, Paba R, Coccia E, et al. Assessment of second (I2M) and third (I3M) molar indices for establishing 14 and 16 legal ages and validation of the Cameriere’s I3M cut-off for 18 years old in Chilean population. Forensic Sci Int. 2018;285:205.e1-205.e5.CrossRefPubMed Cameriere R, Velandia Palacio LA, Pinares J, Bestetti F, Paba R, Coccia E, et al. Assessment of second (I2M) and third (I3M) molar indices for establishing 14 and 16 legal ages and validation of the Cameriere’s I3M cut-off for 18 years old in Chilean population. Forensic Sci Int. 2018;285:205.e1-205.e5.CrossRefPubMed
17.
go back to reference Olze A, Solheim T, Schulz R, Kupfer M, Pfeiffer H, Schmeling A. Assessment of the radiographic visibility of the periodontal ligament in the lower third molars for the purpose of forensic age estimation in living individuals. Int J Legal Med. 2010;124(5):445–8.CrossRefPubMed Olze A, Solheim T, Schulz R, Kupfer M, Pfeiffer H, Schmeling A. Assessment of the radiographic visibility of the periodontal ligament in the lower third molars for the purpose of forensic age estimation in living individuals. Int J Legal Med. 2010;124(5):445–8.CrossRefPubMed
18.
go back to reference Guo YC, Wang YH, Olze A, Schmidt S, Schulz R, Pfeiffer H, et al. Dental age estimation based on the radiographic visibility of the periodontal ligament in the lower third molars: application of a new stage classification. Int J Legal Med. 2020;134(1):369–74.CrossRefPubMed Guo YC, Wang YH, Olze A, Schmidt S, Schulz R, Pfeiffer H, et al. Dental age estimation based on the radiographic visibility of the periodontal ligament in the lower third molars: application of a new stage classification. Int J Legal Med. 2020;134(1):369–74.CrossRefPubMed
19.
go back to reference Halabi SS, Prevedello LM, Kalpathy-cramer J, Mamonov AB. The RSNA Pediatric Bone Age Machine Learning Challenge. 2018; Halabi SS, Prevedello LM, Kalpathy-cramer J, Mamonov AB. The RSNA Pediatric Bone Age Machine Learning Challenge. 2018;
20.
go back to reference Dallora AL, Anderberg P, Kvist O, Mendes E, Ruiz SD, Berglund JS. Bone age assessment with various machine learning techniques: a systematic literature review and meta-analysis. PLoS ONE. 2019;14(7):1–22.CrossRef Dallora AL, Anderberg P, Kvist O, Mendes E, Ruiz SD, Berglund JS. Bone age assessment with various machine learning techniques: a systematic literature review and meta-analysis. PLoS ONE. 2019;14(7):1–22.CrossRef
21.
go back to reference Tao J, Wang J, Wang A, Xie Z, Wang Z, Wu S, et al. Dental Age Estimation: A Machine Learning Perspective. In: Hassanien AE, Azar AT, Gaber T, Bhatnagar R, F. Tolba M, editors. The International Conference on Advanced Machine Learning Technologies and Applications (AMLTA2019). Cham: Springer International Publishing; 2020. p. 722–33. Tao J, Wang J, Wang A, Xie Z, Wang Z, Wu S, et al. Dental Age Estimation: A Machine Learning Perspective. In: Hassanien AE, Azar AT, Gaber T, Bhatnagar R, F. Tolba M, editors. The International Conference on Advanced Machine Learning Technologies and Applications (AMLTA2019). Cham: Springer International Publishing; 2020. p. 722–33.
22.
go back to reference Galibourg A, Cussat-Blanc S, Dumoncel J, Telmon N, Monsarrat P, Maret D. Comparison of different machine learning approaches to predict dental age using Demirjian’s staging approach. Int J Legal Med. 2021;135(2):665–75.CrossRefPubMed Galibourg A, Cussat-Blanc S, Dumoncel J, Telmon N, Monsarrat P, Maret D. Comparison of different machine learning approaches to predict dental age using Demirjian’s staging approach. Int J Legal Med. 2021;135(2):665–75.CrossRefPubMed
23.
go back to reference Cameriere R, de Angelis D, Ferrante L, Scarpino F, Cingolani M. Age estimation in children by measurement of open apices in teeth: a European formula. Int J Legal Med. 2007;121(6):449–53.CrossRefPubMed Cameriere R, de Angelis D, Ferrante L, Scarpino F, Cingolani M. Age estimation in children by measurement of open apices in teeth: a European formula. Int J Legal Med. 2007;121(6):449–53.CrossRefPubMed
24.
go back to reference A. Demirjian et al. A New System of Dental Age Assessment Author ( s ): A . Demirjian , H . Goldstein and J . M . Tanner Published by : Wayne State University Press Stable URL : http://www.jstor.org/stable/41459864 REFERENCES Linked references are available on JSTOR for this. Hum Biol. 1973;45(2):211–27. A. Demirjian et al. A New System of Dental Age Assessment Author ( s ): A . Demirjian , H . Goldstein and J . M . Tanner Published by : Wayne State University Press Stable URL : http://​www.​jstor.​org/​stable/​41459864 REFERENCES Linked references are available on JSTOR for this. Hum Biol. 1973;45(2):211–27.
25.
go back to reference Wang M, Wang J, Pan Y, Fan L, Shen Z, Ji F, et al. Applicability of newly derived second and third molar maturity indices for indicating the legal age of 16 years in the Southern Chinese population. Leg Med. 2020;46:101725.CrossRef Wang M, Wang J, Pan Y, Fan L, Shen Z, Ji F, et al. Applicability of newly derived second and third molar maturity indices for indicating the legal age of 16 years in the Southern Chinese population. Leg Med. 2020;46:101725.CrossRef
26.
go back to reference Balla SB, Chinni SS, Galic I, Alwala AM, Machani P, Cameriere R. A cut-off value of third molar maturity index for indicating a minimum age of criminal responsibility: Older or younger than 16 years? J Forensic Leg Med. 2018;2019(65):108–12. Balla SB, Chinni SS, Galic I, Alwala AM, Machani P, Cameriere R. A cut-off value of third molar maturity index for indicating a minimum age of criminal responsibility: Older or younger than 16 years? J Forensic Leg Med. 2018;2019(65):108–12.
27.
go back to reference Deitos AR, Costa C, Michel-Crosato E, Galić I, Cameriere R, Biazevic MGH. Age estimation among Brazilians: younger or older than 18? J Forensic Leg Med. 2015;33:111–5.CrossRefPubMed Deitos AR, Costa C, Michel-Crosato E, Galić I, Cameriere R, Biazevic MGH. Age estimation among Brazilians: younger or older than 18? J Forensic Leg Med. 2015;33:111–5.CrossRefPubMed
Metadata
Title
Using machine learning to determine age over 16 based on development of third molar and periodontal ligament of second molar
Authors
Shihui Shen
Zhuojun Zhou
Jian Wang
Linfeng Fan
Junli Han
Jiang Tao
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-023-03284-5

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