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Published in: European Radiology 10/2010

Open Access 01-10-2010 | Breast

Using computer-aided detection in mammography as a decision support

Authors: Maurice Samulski, Rianne Hupse, Carla Boetes, Roel D. M. Mus, Gerard J. den Heeten, Nico Karssemeijer

Published in: European Radiology | Issue 10/2010

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Abstract

Objective:

To evaluate an interactive computer-aided detection (CAD) system for reading mammograms to improve decision making.

Methods:

A dedicated mammographic workstation has been developed in which readers can probe image locations for the presence of CAD information. If present, CAD findings are displayed with the computed malignancy rating. A reader study was conducted in which four screening radiologists and five non-radiologists participated to study the effect of this system on detection performance. The participants read 120 cases of which 40 cases had a malignant mass that was missed at the original screening. The readers read each mammogram both with and without CAD in separate sessions. Each reader reported localized findings and assigned a malignancy score per finding. Mean sensitivity was computed in an interval of false-positive fractions less than 10%.

Results:

Mean sensitivity was 25.1% in the sessions without CAD and 34.8% in the CAD-assisted sessions. The increase in detection performance was significant (p = 0.012). Average reading time was 84.7 ± 61.5 s/case in the unaided sessions and was not significantly higher when interactive CAD was used (85.9 ± 57.8 s/case).

Conclusion:

Interactive use of CAD in mammography may be more effective than traditional CAD for improving mass detection without affecting reading time.
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Metadata
Title
Using computer-aided detection in mammography as a decision support
Authors
Maurice Samulski
Rianne Hupse
Carla Boetes
Roel D. M. Mus
Gerard J. den Heeten
Nico Karssemeijer
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
European Radiology / Issue 10/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1821-8

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