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Acta Neurochirurgica

Published in:

01-01-2009 | Neurosurgical Techniques

Use of a thrombin–gelatin haemostatic matrix in endoscopic endonasal extended approaches: technical note

Authors: Paolo Cappabianca, Felice Esposito, Isabella Esposito, Luigi Maria Cavallo, Carlo Antonio Leone

Published in: Acta Neurochirurgica | Issue 1/2009

Abstract

Objective

The management of intradural bleeding during extended endoscopic endonasal surgery is challenging. This technical note describes the use of a biological haemostatic agent which could be useful when other established strategies and materials are not effective.

Materials and methods

From January 2004 to January 2008, 65 consecutive patients underwent extended endoscopic endonasal interventions. Of these, 29 procedures required the application of a thrombin–gelatin haemostatic matrix. We reviewed the patients’ operative records to determine the source, type of bleeding and haemostatic strategy.

Results

We analysed bleedings from the venous sinuses, arteries, tumour bed and internal carotid artery and observed complete haemostasis immediately after application of FloSeal®. The matrix was useful for both oozing and focal haemorrhage and effective even for high-flow bleeding. Only bleeding from an internal carotid artery tear required a second application.

Conclusion

The thrombin–gelatin matrix could represent a valuable tool when other haemostatic strategies are ineffective or suboptimal. It is safe and biocompatible when compared with haemostatic agents currently in use.

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Title: Use of a thrombin–gelatin haemostatic matrix in endoscopic endonasal extended approaches: technical note
Authors: Paolo Cappabianca
Felice Esposito
Isabella Esposito
Luigi Maria Cavallo
Carlo Antonio Leone
Publication date: 01-01-2009
Publisher: Springer Vienna
Published in: Acta Neurochirurgica / Issue 1/2009
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-008-0172-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Use of a thrombin–gelatin haemostatic matrix in endoscopic endonasal extended approaches: technical note

Abstract

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

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