Published in:
Open Access
01-02-2011 | Poster presentation
Urine biomarkers for gentamicin-induced acute kidney injury in the neonatal ICU
Authors:
D Jansen, S Heemskerk, L Koster-Kamphuis, TP Bouw, AF Heijst, P Pickkers
Published in:
Critical Care
|
Special Issue 1/2011
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Excerpt
Gentamicin (GM) is an aminoglycoside frequently used in the neonatal ICU to treat infections. Despite low resistance and costs, GM is also nephrotoxic and may cause acute kidney injury (AKI). Serum creatinine appears to be an insensitive and unreliable marker in this setting. The objective of this study was to determine whether urine biomarkers are useful for early detection of gentamicin-induced AKI in neonates in the neonatal ICU. …