Published in:
01-04-2011 | Reviews
Update in New Medications for Primary Care
Authors:
Gerald W. Smetana, MD, Jane S. Sillman, MD
Published in:
Journal of General Internal Medicine
|
Issue 4/2011
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Excerpt
General internists must capably prescribe hundreds of medications across multiple different categories. While most new drugs each year represent “me too” drugs that are simply new drugs within an existing class, a small number of drugs each year work through a completely novel mechanism and are potentially relevant for primary care practice. It is difficult to keep up with advances in pharmacotherapy and to obtain balanced information regarding comparative efficacy, side effects, and cost. In order to identify potentially relevant novel drugs, we searched the drugs@FDA database,
1 polled our institutional pharmacists, performed a lay Internet search for news stories, and reviewed the following journals for the period of January 1, 2009 through April 1, 2010: New England Journal of Medicine, Annals of Internal Medicine, ACP Journal Club, JAMA, Journal Watch, The Medical Letter, Medical Letter Treatment Updates, and the Lancet. We have chosen to discuss one recently approved drug and one novel drug in the pipeline: dronedarone for the treatment of atrial fibrillation and roflumilast as a controller medication for chronic obstructive pulmonary disease. …