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Published in: Rheumatology International 1/2007

01-11-2007 | Case Report

Unilateral cervical mass as a main clue raising the diagnostic suspicion of Kawasaki syndrome

Authors: D. Rigante, I. La Torraca, A. Rossodivita, G. De Rosa, A. Pantanella, A. B. Delogu, S. Gaspari, A. Stabile

Published in: Rheumatology International | Issue 1/2007

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Abstract

Unilateral cervical mass and fever were firstly misdiagnosed as bacterial lymphadenitis in a 6-year-old child and empirically treated with antibiotics. Later the child developed the additional features of Kawasaki syndrome and received intravenous immunoglobulins at the eighth day since fever onset with progressive disappearance of the cervical mass and no cardiac sequel. Kawasaki syndrome should be considered in childhood as a relevant cause of cervical lymphadenopathy unresponding to antibiotics: its recognition at an early stage might contribute to anticipate a proper treatment and abate heart complication rate.
Literature
1.
go back to reference Kawasaki T, Kosaki F, Osawa S, Shigematsu I, Yanagawa H (1974) A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. Pediatrics 54:271–276PubMed Kawasaki T, Kosaki F, Osawa S, Shigematsu I, Yanagawa H (1974) A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. Pediatrics 54:271–276PubMed
2.
go back to reference Durongpisitkul K, Gururaj VJ, Park JM, Martin CF (1995) The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics 96:1057–1061PubMed Durongpisitkul K, Gururaj VJ, Park JM, Martin CF (1995) The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics 96:1057–1061PubMed
3.
go back to reference Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, Shulman ST, Bolger AF, Ferrieri P, Baltimore RS, Wilson WR, Baddour LM, Levison ME, Pallasch TJ, Falace DA, Taubert KA (2004) Committee on rheumatic fever, endocarditis and Kawasaki disease, council on cardiovascular disease in the young; american heart association, american academy of pediatricsdiagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the committee on rheumatic fever, endocarditis and Kawasaki disease, council on cardiovascular disease in the young, American heart association. Circulation 110:2747–2771PubMedCrossRef Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, Shulman ST, Bolger AF, Ferrieri P, Baltimore RS, Wilson WR, Baddour LM, Levison ME, Pallasch TJ, Falace DA, Taubert KA (2004) Committee on rheumatic fever, endocarditis and Kawasaki disease, council on cardiovascular disease in the young; american heart association, american academy of pediatricsdiagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the committee on rheumatic fever, endocarditis and Kawasaki disease, council on cardiovascular disease in the young, American heart association. Circulation 110:2747–2771PubMedCrossRef
5.
go back to reference Burns JC, Mason WH, Glode MP, Shulman ST, Melish ME, Meissner C, Bastian J, Beiser AS, Meyerson HM, Newburger JW (1991) Clinical and epidemiologic characteristics of patients referred for evaluation of possible Kawasaki disease. J Pediatr 118:680–686PubMedCrossRef Burns JC, Mason WH, Glode MP, Shulman ST, Melish ME, Meissner C, Bastian J, Beiser AS, Meyerson HM, Newburger JW (1991) Clinical and epidemiologic characteristics of patients referred for evaluation of possible Kawasaki disease. J Pediatr 118:680–686PubMedCrossRef
6.
go back to reference April MM, Burns JC, Newburger JW, Healy GB (1989) Kawasaki disease and cervical adenopathy. Arch Otolaryngol Head Neck Surg 115:512–514PubMed April MM, Burns JC, Newburger JW, Healy GB (1989) Kawasaki disease and cervical adenopathy. Arch Otolaryngol Head Neck Surg 115:512–514PubMed
7.
go back to reference Cengiz AB, Kara A, Kanra G, Secmeer G, Ceyhan M, Ozen M (2004) Acute neck infections in children. Turk J Pediatr 46:153–158PubMed Cengiz AB, Kara A, Kanra G, Secmeer G, Ceyhan M, Ozen M (2004) Acute neck infections in children. Turk J Pediatr 46:153–158PubMed
8.
go back to reference Rigante D, Spanu T, Nanni L, Tornesello A, Sanguinetti M, D’Inzeo T, Stabile A, Fadda A (2006) Deep neck infection complicating lymphadenitis caused by Streptococcus intermedius in an immunocompetent child. BMC Infect Dis 6:61PubMedCrossRef Rigante D, Spanu T, Nanni L, Tornesello A, Sanguinetti M, D’Inzeo T, Stabile A, Fadda A (2006) Deep neck infection complicating lymphadenitis caused by Streptococcus intermedius in an immunocompetent child. BMC Infect Dis 6:61PubMedCrossRef
9.
go back to reference Ammari FF, Bani Hani AH, Ghariebeh KI (2003) Tuberculosis of the lymph glands of the neck: a limited role for surgery. Otolaryngol Head Neck Surg 128:576–580PubMedCrossRef Ammari FF, Bani Hani AH, Ghariebeh KI (2003) Tuberculosis of the lymph glands of the neck: a limited role for surgery. Otolaryngol Head Neck Surg 128:576–580PubMedCrossRef
10.
go back to reference Moore SW, Schneider JW, Schaaf HS (2003) Diagnostic aspects of cervical lymphadenopathy in children in the developing world: a study of 1,877 surgical specimens. Pediatr Surg Int 19:240–244PubMedCrossRef Moore SW, Schneider JW, Schaaf HS (2003) Diagnostic aspects of cervical lymphadenopathy in children in the developing world: a study of 1,877 surgical specimens. Pediatr Surg Int 19:240–244PubMedCrossRef
11.
go back to reference Oguz A, Karadeniz C, Temel EA, Citak EC, Okur FV (2006) Evaluation of peripheral lymphadenopathy in children. Pediatr Hematol Oncol 23:549–561PubMedCrossRef Oguz A, Karadeniz C, Temel EA, Citak EC, Okur FV (2006) Evaluation of peripheral lymphadenopathy in children. Pediatr Hematol Oncol 23:549–561PubMedCrossRef
12.
go back to reference Daneshbod Y, Banani A, Kumar PV (2006) Aberrant thymus and parathyroid gland presenting as a recurrent lateral neck mass: a case report. Ear Nose Throat J 85:452–453PubMed Daneshbod Y, Banani A, Kumar PV (2006) Aberrant thymus and parathyroid gland presenting as a recurrent lateral neck mass: a case report. Ear Nose Throat J 85:452–453PubMed
13.
go back to reference Wang TJ, Yang YH, Lin YT, Chiang BL (2004) Kikuchi-Fujimoto disease in children: clinical features and disease course. J Microbiol Immunol Infect 37:219–224PubMed Wang TJ, Yang YH, Lin YT, Chiang BL (2004) Kikuchi-Fujimoto disease in children: clinical features and disease course. J Microbiol Immunol Infect 37:219–224PubMed
14.
go back to reference Baserga M, Rosin M, Schoen M, Young G (2005) Multifocal Castleman disease in pediatrics: case report. J Pediatr Hematol Oncol 27:666–669PubMedCrossRef Baserga M, Rosin M, Schoen M, Young G (2005) Multifocal Castleman disease in pediatrics: case report. J Pediatr Hematol Oncol 27:666–669PubMedCrossRef
15.
go back to reference Ruggiero A, Attinà G, Maurizi P, Mulé A, Tarquini E, Barone G, Lazzareschi I, Riccardi R (2006) Rosai-Dorfman disease: two case reports and diagnostic role of fine-needle aspiration cytology. J Pediatr Hematol Oncol 28:103–106PubMedCrossRef Ruggiero A, Attinà G, Maurizi P, Mulé A, Tarquini E, Barone G, Lazzareschi I, Riccardi R (2006) Rosai-Dorfman disease: two case reports and diagnostic role of fine-needle aspiration cytology. J Pediatr Hematol Oncol 28:103–106PubMedCrossRef
16.
go back to reference Stamos JK, Corydon K, Donaldson J, Shulman ST (1994) Lymphadenitis as the dominating manifestation of Kawasaki disease. Pediatrics 93:525–528PubMed Stamos JK, Corydon K, Donaldson J, Shulman ST (1994) Lymphadenitis as the dominating manifestation of Kawasaki disease. Pediatrics 93:525–528PubMed
17.
go back to reference Fan PC, Chiu CH, Yen MH, Huang YC, Li CC, Lin TY (2003) School-aged children with Kawasaki disease: high incidence of cervical lymphadenopathy and coronary artery involvement. J Paediatr Child Health 39:55–57PubMedCrossRef Fan PC, Chiu CH, Yen MH, Huang YC, Li CC, Lin TY (2003) School-aged children with Kawasaki disease: high incidence of cervical lymphadenopathy and coronary artery involvement. J Paediatr Child Health 39:55–57PubMedCrossRef
18.
go back to reference Kao HT, Huang YC, Lin TY (2001) Kawasaki disease presenting as cervical lymphadenitis or deep neck infection. Otolaryngol Head Neck Surg 124:468–470PubMedCrossRef Kao HT, Huang YC, Lin TY (2001) Kawasaki disease presenting as cervical lymphadenitis or deep neck infection. Otolaryngol Head Neck Surg 124:468–470PubMedCrossRef
19.
go back to reference April MM, Burns JC, Newburger JW, Healy GB (1989) Kawasaki disease and cervical adenopathy. Arch Otolaryngol Head Neck Surg 115:512–514PubMed April MM, Burns JC, Newburger JW, Healy GB (1989) Kawasaki disease and cervical adenopathy. Arch Otolaryngol Head Neck Surg 115:512–514PubMed
20.
go back to reference Giesker DW, Pastuszak WT, Forouhar FA, Krause PJ, Hine P (1982) Lymph node biopsy for early diagnosis in Kawasaki disease. Am J Surg Pathol 6:493–501PubMedCrossRef Giesker DW, Pastuszak WT, Forouhar FA, Krause PJ, Hine P (1982) Lymph node biopsy for early diagnosis in Kawasaki disease. Am J Surg Pathol 6:493–501PubMedCrossRef
21.
go back to reference Douglas SA, Jennings S, Owen VM, Elliott S, Parker D (2005) Is ultrasound useful for evaluating paediatric inflammatory neck masses? Clin Otolaryngol 30:526–529PubMedCrossRef Douglas SA, Jennings S, Owen VM, Elliott S, Parker D (2005) Is ultrasound useful for evaluating paediatric inflammatory neck masses? Clin Otolaryngol 30:526–529PubMedCrossRef
22.
go back to reference Tashiro N, Matsubara T, Uchida M, Katayama K, Ichiyama T, Furukawa S (2001) Ultrasonographic evaluation of cervical lymph nodes in Kawasaki disease. Pediatrics 109:E77CrossRef Tashiro N, Matsubara T, Uchida M, Katayama K, Ichiyama T, Furukawa S (2001) Ultrasonographic evaluation of cervical lymph nodes in Kawasaki disease. Pediatrics 109:E77CrossRef
Metadata
Title
Unilateral cervical mass as a main clue raising the diagnostic suspicion of Kawasaki syndrome
Authors
D. Rigante
I. La Torraca
A. Rossodivita
G. De Rosa
A. Pantanella
A. B. Delogu
S. Gaspari
A. Stabile
Publication date
01-11-2007
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 1/2007
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-007-0378-6

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