Published in:
01-01-2017 | Understanding the Disease
Understanding the Haldane effect
Authors:
Jean-Louis Teboul, Thomas Scheeren
Published in:
Intensive Care Medicine
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Issue 1/2017
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Excerpt
Several studies have proposed using either the venous-to-arterial carbon dioxide (CO2) content (CCO2) or the venous-to-arterial CO2 pressure (PCO2) difference to assess systemic hypoperfusion or tissue hypoxia. However, these two variables sometimes differ at the highest levels of CCO2 because of the complex relationship between CCO2 and PCO2 involving the Haldane effect. …